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First Report of blaOXA-181-Carrying IncX3 Plasmids in Multidrug-Resistant Enterobacter hormaechei and Serratia Nevei Recovered From Canine and Feline Opportunistic Infections. [PDF]

open access: yesMicrobiology Spectrum
Whole-genome sequence analysis of six Enterobacter hormaechei and two Serratia nevei strains, using a hybrid assembly of Illumina and Oxford Nanopore Technologies sequencing, revealed the presence of the epidemic blaOXA-181-carrying IncX3 plasmids co ...
Vincent Perreten   +2 more
exaly   +7 more sources

In Silico Characterization of IncX3 Plasmids Carrying blaOXA-181 in Enterobacterales [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhijian Yu, Xiaobin Li, Qiuping Lin
exaly   +4 more sources

Prevalence of carbapenem-resistant Enterobacteriaceae and emergence of high rectal colonization rates of blaOXA-181-positive isolates in patients admitted to two major hospital intensive care units in Kuwait. [PDF]

open access: yesPLoS ONE, 2020
BackgroundFecal colonization by carbapenem-resistant Enterobacteriaceae (CRE) can be the main reservoir for transmission of these resistant organisms especially in the Intensive Care Units (ICUs).AimThis study was conducted to evaluate the rate of rectal
Amani H Al Fadhli   +2 more
doaj   +3 more sources

Isolation of Hv-CRKP With Co-Production of Three Carbapenemases (blaKPC, blaOXA-181 or OXA-232, and blaNDM-1) and a Virulence Plasmid: A Study From a Chinese Tertiary Hospital [PDF]

open access: yesFrontiers in Microbiology, 2023
BackgroundThe worldwide dissemination of K. pneumoniae isolates is a significant public health concern, as these organisms possess a unique capacity to acquire genetic elements encoding both resistance and hypervirulence.
Dan-Dan Wei, La-Gen Wan, Tian-Xin Xiang
exaly   +4 more sources

Emergence of Salmonella enterica carrying blaOXA-181 carbapenemase gene, Italy, 2021 to 2024 [PDF]

open access: yesEurosurveillance
Between 2021 and 2024, we detected carbapenemase gene blaOXA-181 in 16 of 11,398 Salmonella enterica (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer. The gene was first
Stefano Pongolini
doaj   +3 more sources

A blaOXA-181-harbouring multi-resistant ST147 Klebsiella pneumoniae isolate from Pakistan that represent an intermediate stage towards pan-drug resistance. [PDF]

open access: yesPLoS ONE, 2017
Carbapenem resistant Klebsiella pneumoniae (CR-KP) infections are an ever-increasing global issue, especially in the Indian subcontinent. Here we report genetic insight into a blaOXA-181 harbouring Klebsiella pneumoniae, belonging to the pandemic lineage
Fouzia Nahid   +2 more
doaj   +3 more sources

Klebsiella Species and Enterobacter cloacae Isolates Harboring blaOXA-181 and blaOXA-48: Resistome, Fitness Cost, and Plasmid Stability [PDF]

open access: yesMicrobiology Spectrum, 2022
IncX3 and IncL plasmids have been named as catalysts advancing dissemination of blaOXA-181 and blaOXA-48 genes. However, their impact on the performance of host cells is vastly understudied. Genetic characteristics of blaOXA-48- and blaOXA-181-containing
Samiratu Mahazu   +11 more
doaj   +2 more sources

Comparative Genomic Analysis of Plasmids Harboring blaOXA-48-Like Genes in Klebsiella pneumoniae

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
The emergence and spread of carbapenem-resistant Klebsiella pneumoniae (CRKP) is a serious medical problem worldwide. Acquired OXA-48-like carbapenemases encoded by plasmids are important causes of carbapenem resistance in K. pneumoniae.
Hengzhao Guo
exaly   +3 more sources

Klebsiella pneumoniae ST307 with blaOXA-181, South Africa, 2014–2016 [PDF]

open access: yesEmerging Infectious Diseases, 2019
Klebsiella pneumoniae sequence type (ST) 307 is an emerging global antimicrobial drug–resistant clone. We used whole-genome sequencing and PCR to characterize K.
Michelle Lowe   +14 more
doaj   +2 more sources

Genomic landscape of blaNDM-1- and blaOXA-181-carrying Citrobacter portucalensis sequence type 151 strains from hospital wastewater in Ghana [PDF]

open access: yesApplied and Environmental Microbiology
Carbapenemases represent one of the major driving forces of antimicrobial resistance (AMR), which has been recognized as a significant public health concern.
Frederick Ofosu Appiah   +10 more
doaj   +2 more sources

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