Genomic landscape of blaNDM-1- and blaOXA-181-carrying Citrobacter portucalensis sequence type 151 strains from hospital wastewater in Ghana [PDF]
Carbapenemases represent one of the major driving forces of antimicrobial resistance (AMR), which has been recognized as a significant public health concern.
Frederick Ofosu Appiah +10 more
doaj +2 more sources
Oxacillinase-181 Carbapenemase-Producing Klebsiella pneumoniae in Neonatal Intensive Care Unit, Ghana, 2017–2019 [PDF]
We sequenced 29 carbapenemase-producing Klebsiella pneumoniae isolates from a neonatal intensive care unit in Ghana. Twenty-eight isolates were sequence type 17 with blaOXA-181 and differed by 0–32 single-nucleotide polymorphisms.
Appiah-Korang Labi +9 more
doaj +3 more sources
Limits of rapid diagnostics: genomic and structural insights into OXA-48–like mediated carbapenem resistance in Escherichia coli [PDF]
Carbapenem-resistant Escherichia coli (CREC) represent a major clinical threat because of limited treatment options and frequent multidrug resistance.
Aya A. Diab +13 more
doaj +2 more sources
Epidemiology of Carbapenemase-Producing Klebsiella pneumoniae in a Hospital, Portugal [PDF]
We aimed to provide updated epidemiologic data on carbapenem-resistant Klebsiella pneumoniae in Portugal by characterizing all isolates (N = 46) recovered during 2013–2018 in a 123-bed hospital in Lisbon.
Marta Aires-de-Sousa +5 more
doaj +3 more sources
Purpose: To understand the mechanisms of carbapenem-resistant Klebsiella pneumoniae (CRKP) from Tanzania and characterize the genomes carrying the carbapenemase genes.
Lawrence Mapunda +6 more
doaj +3 more sources
Characterization of the First Carbapenem-Resistant Pseudocitrobacter faecalis Harboring blaOXA-181 in China. [PDF]
With the wide use of carbapenems, carbapenem-resistant Enterobacterales have been increasingly reported worldwide. In this study, one blaOXA-181-positive Pseudocitrobacter faecalis strain was isolated from the blood culture of a patient with a bloodstream infection in China, which was its first clinical report outside Pakistan.
Shi Q +7 more
europepmc +4 more sources
Emergence of bla<sub>OXA-181</sub>-bearing tigecycline-resistant Klebsiella aerogenes in China. [PDF]
We report the isolation of a blaOXA-181-positive, tigecycline-resistant Klebsiella aerogenes strain KA04 from a Chinese inpatient's fecal sample. Species identification was performed using MALDI-TOF MS. The antibiotic susceptibilities were assessed via the broth microdilution method. To elucidate the transmission and genetic structure of the blaOXA-181
Fang Y +8 more
europepmc +4 more sources
Freshwater snail faecal metagenomes reveal environmental reservoirs of antimicrobial resistance genes across two continents. [PDF]
The transfer of antimicrobial resistance genes (ARGs) from environmental microbes to pathogens is a critical but underexplored One Health driver of antimicrobial resistance. Here, we evaluate freshwater snails, which are geographically widespread aquatic
O'Ferrall AM +12 more
europepmc +3 more sources
Erratum for Mahazu et al., "<i>Klebsiella</i> Species and <i>Enterobacter cloacae</i> Isolates Harboring <i>bla</i> <sub>OXA-181</sub> and <i>bla</i> <sub>OXA-48</sub>: Resistome, Fitness Cost, and Plasmid Stability". [PDF]
Mahazu S +11 more
europepmc +3 more sources
Detection of OXA-181-producing Pseudomonas aeruginosa in Germany
Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: Carbapenemase detection was performed by using several phenotypic tests such as the modified Hodge test, a ...
Jennifer Schauer +4 more
doaj +1 more source

