Results 11 to 20 of about 22,689,515 (154)

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High‐Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa [PDF]

MicrobiologyOpen
Asymptomatic rectal carriers are recognized as reservoirs of carbapenem‐resistant Klebsiella pneumoniae (CRKp), which can spread epidemic high‐risk clones [e.g., sequence types (ST)‐307] and plasmids [incompatibility group (Inc)‐X3] in hospitals, with ...
Kafilat Taiwo Salvador‐Oke, Johann Pitout, Gisele Peirano, Kathy‐Anne Strydom, Chanel Kingsburgh, Marthie Ehlers, Marleen Kock   +6 more
doaj   +3 more sources

Occurrence and spread of carbapenemase‐producing Enterobacterales (CPE) in the food chain in the EU/EFTA. Part 1: 2025 update

EFSA Journal
Carbapenemase‐producing Enterobacterales (CPE) have been reported in the food chain in 14 out of 30 EU/EFTA countries. Commonly reported genes are blaVIM‐1, blaOXA‐48 and blaOXA‐181, followed by blaNDM‐5 and blaIMI‐1.
EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), Ana Allende, Avelino Álvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Fernando Pérez‐Rodríguez, Panagiotis Skandamis, Elisabetta Suffredini, Hector Argüello, Johan Bengtsson‐Palme, Alessandra Carattoli, Anke Kohlenberg, Dominique L. Monnet, Laurent Poirel, Beatriz Guerra, Raquel García‐Fierro, Ernesto Liébana, Sonagnon Martin Goudjihounde, Núria Ferrer‐Bustins, Hanne Rabbås, Luisa Peixe   +28 more
doaj   +3 more sources

First Report of OXA-181-Producing Enterobacterales Isolates in Latin America

Microbiology Spectrum, 2023
We characterized five carbapenemase-producing Enterobacterales (CPE) isolates from two health care institutions in Lima, Peru. The isolates were identified as Klebsiella pneumoniae (n = 3), Citrobacter portucalensis (n = 1), and Escherichia coli (n = 1).
Diego Cuicapuza, Luis Alvarado, Norah Tocasca, Daniel Aguilar, Juan Carlos Gómez-de-la-Torre, Guillermo Salvatierra, Pablo Tsukayama, Jesús Tamariz   +7 more
doaj   +2 more sources

Detection of OXA-181/OXA-48 carbapenemase producing Enterobacteriaceae in Bangladesh

IMC Journal of Medical Science, 2015
Carbapenem resistant Enterobacteriaceae (CRE) is becoming a major public health concern globally. Detection of carbapenem hydrolyzing enzyme carbapenemase in Enterobacteriaceae is important to institute appropriate therapy and to initiate preventive ...
Rehana Khatun, S.M. Shamsuzzaman
doaj   +1 more source

Phenotypic and Genotypic Characterization of Enterobacteriaceae Producing Oxacillinase-48–Like Carbapenemases, United States

Emerging Infectious Diseases, 2018
Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the United States. We performed phenotypic and genotypic characterization of 30 Enterobacteriaceae producing OXA-48–like carbapenemases that were recovered from patients during 2010 ...
Joseph D. Lutgring, Wenming Zhu, Tom J.B. de Man, Johannetsy J. Avillan, Karen F. Anderson, David R. Lonsway, Lori A. Rowe, Dhwani Batra, J. Kamile Rasheed, Brandi M. Limbago   +9 more
doaj   +2 more sources

A case of carbapenamase production in Shigella flexneri isolated in Ireland, 2025 [PDF]

Eurosurveillance
Shigella flexneri producing OXA-181 was detected from a patient in Ireland in October 2025. The isolate had a meropenem minimum inhibitory concentration (MIC) of 0.12 mg/L. Carbapenemase production was detected by lateral flow immunoassay.
Martin Cormican
doaj   +2 more sources

Limits of rapid diagnostics: genomic and structural insights into OXA-48–like mediated carbapenem resistance in Escherichia coli [PDF]

Frontiers in Microbiology
Carbapenem-resistant Escherichia coli (CREC) represent a major clinical threat because of limited treatment options and frequent multidrug resistance.
Aya A. Diab, Deena Jalal, Youssef M. Fadel, Omar Samir, Lobna Shalaby, Lobna Shalaby, Mervat Elanany, Mervat Elanany, Sabah A. Abo-Elmaaty, Ramy K. Aziz, Ramy K. Aziz, Ahmed AbdelAziz Sayed, Ahmed AbdelAziz Sayed, Mervat G. Hassan   +13 more
doaj   +2 more sources

Intra- and Interspecies Spread of a Novel Conjugative Multidrug Resistance IncC Plasmid Coharboring bla_OXA-181 and armA in a Cystic Fibrosis Patient. [PDF]

Microbiol Spectr, 2022
A novel multidrug resistance conjugative 177,859-bp IncC plasmid pJEF1-OXA-181 coharboring the carbapenemase-coding blaOXA181 and the aminoglycoside resistance 16S rRNA methyltransferase-coding armA genes was detected in two unrelated Escherichia coli ...
Fernandez JE, Seth-Smith HMB, Nordmann P, Egli A, Endimiani A, Perreten V.   +5 more
europepmc   +3 more sources

Co-existence of two blaNDM-5 and blaOXA-181 on distinct plasmids in a carbapenem-resistant Klebsiella pneumoniae from a tertiary hospital, Tanzania

Journal of Global Antimicrobial Resistance
Purpose: To understand the mechanisms of carbapenem-resistant Klebsiella pneumoniae (CRKP) from Tanzania and characterize the genomes carrying the carbapenemase genes.
Lawrence Mapunda, Anthon Mwingwa, Doreen Kamori, Happiness Kumburu, Marco van Zwetselaar, Bjorn Blomberg, Joel Manyahi   +6 more
doaj   +2 more sources

A Four-Center Study on the Activity of Aztreonam and Aztreonam-Avibactam Combination Against Clinical Isolates of Gram-Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β-Lactamases. [PDF]

APMIS
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Ceviz Gİ, Mirza HC, Güçlü AÜ, Şanlı ÖÖ, Azap ÖK, Sancak B, İştar EH, Başustaoğlu A.   +7 more
europepmc   +2 more sources