Results 11 to 20 of about 2,386 (192)

IncX3 plasmid-mediated spread of blaNDM gene in Enterobacteriaceae among children in China

Journal of Global Antimicrobial Resistance
: Objectives: The blaNDM gene was prevalent among children and became the predominant cause of severe infection in infants and children. This study aimed to investigate the epidemiology and molecular characteristics of blaNDM in Enterobacteriaceae among
Qin Jie, Yijia Li, Pan Fu
exaly   +5 more sources

Molecular Characterization of blaNDM-Carrying IncX3 Plasmids: blaNDM-16b Likely Emerged from a Mutation of blaNDM-5 on IncX3 Plasmid

Microbiology Spectrum, 2022
Dissemination of blaNDM, which is carried on the IncX3 plasmid, among Enterobacterales has been reported worldwide. In particular, blaNDM-5-carrying IncX3 plasmids can spread among several hosts, facilitating their dissemination.
Tsukasa Ariyoshi, Kotaro Aoki, Hiroaki Kubota, Kenji Sadamasu, Yoshikazu Ishii, Kazuhiro Tateda   +5 more
doaj   +4 more sources

In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales

Frontiers in Cellular and Infection Microbiology, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhijian Yu, Zhengrong Zhang, Lile Shi, Shengni Hua, Ting Luan, Qiuping Lin, Zhixiong Zheng, Xiaosan Feng, Mubiao Liu, Xiaobin Li   +9 more
doaj   +3 more sources

IncX3 plasmid mediated occurrence of blaNDM-4 within Escherichia coli ST448 from India [PDF]

Journal of Infection and Public Health, 2018
This study was designed to investigate blaNDM-4 encoded within IncX3 type plasmid and their copy number alteration under carbapenem pressure within clinical isolates of Escherichia coli. NDM-4 producing E.
Nargis A. Choudhury, Deepjyoti Paul, Atanu Chakravarty, Amitabha Bhattacharjee, Debadatta Dhar Chanda   +4 more
doaj   +12 more sources

Fitness Cost of bla_NDM-5-Carrying p3R-IncX3 Plasmids in Wild-Type NDM-Free Enterobacteriaceae [PDF]

Microorganisms, 2020
The wide dissemination of New Delhi metallo-β-lactamase genes (blaNDM) has resulted in the treatment failure of most available β-lactam antibiotics, with IncX3-type blaNDM-5-carrying plasmids recognised as having spread worldwide.
Tengfei Ma, Jiani Fu, Ning Xie, Shizhen Ma, Lei Lei, Weishuai Zhai, Yingbo Shen, Chengtao Sun, Shaolin Wang, Zhangqi Shen, Yang Wang, Timothy R. Walsh, Jianzhong Shen   +12 more
doaj   +3 more sources

Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying blaKPC-2 in a Klebsiella pneumoniae [PDF]

Current Microbiology, 2013
The IncX family of plasmids has recently been expanded to include at least four subtypes, IncX1-IncX4. The revised classification provides an opportunity for improving our understanding of the sequence diversity of the IncX plasmids and the resistance ...
Chan, JFW, Cheng, VCC, CHEUNG, YY, Chow, KH, Ho, PL, LI, Z, Lin, C, Lo, WU   +7 more
core   +5 more sources

Characterization of blaNDM-19-producing IncX3 plasmid isolated from carbapenem-resistant Escherichia coli and Klebsiella pneumoniae

Heliyon, 2023
The increase in the prevalence of carbapenem-producing Enterobacterales (CPE) is a major threat, with the New Delhi metallo-β-lactamase (NDM) enzyme-producing CPEs being one of the major causative agents of healthcare settings infections.
Jennifer Moussa, Elie Nassour, Tamima Jisr, Mira El Chaar, Sima Tokajian   +4 more
doaj   +3 more sources

IncX3 plasmid carrying blaSHV-12 and qnrS1 in a Japanese racehorse-origin Escherichia coli isolate [PDF]

Veterinarski Glasnik
Plasmids play an important role in the spread of antimicrobial resistance genes (ARGs) in bacteria. This study reports the complete sequence of the IncX3 plasmid identified in Escherichia coli isolated from faeces of a Japanese racehorse.
Sukmawinata Eddy, Uemura Ryoko, Nishiki Issei, Yoshida Terutoyo, Sueyoshi Masuo, Kikuchi Taisei   +5 more
doaj   +2 more sources

Global phylogenetic analysis and emergence of carbapenem-resistant Escherichia fergusonii carrying blaNDM-5 in clinic [PDF]

One Health
Background: Escherichia fergusonii, a newly recognized Enterobacterale member, has gained attention due to the blaNDM-5 resistance gene found in animals. However, to date, no clinical isolates carrying this gene have been reported.
Xinru Wang, Ying Zhang, Jie Sheng, Longjie Zhou, Jiayao Yao, Yueyue Hu, Xiufang Xu, Yunsong Yu, Xi Li   +8 more
doaj   +2 more sources

Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger. [PDF]

Nat Commun
Hospitalisation and routine antibiotic treatment are recommended for children with complicated severe acute malnutrition (SAM) but this may exacerbate antimicrobial resistance.
Sands K, Lankapalli AK, Lai G, Hassan B, Portal EA, Mathias JA, Boostrom I, Li M, Cook K, Premchand-Branker S, Jones LS, Sayinzonga-Makombe N, Isanaka S, Kanapathipillai R, Mambula C, Mouniaman I, Langendorf C, Walsh TR, Spiller OB.   +18 more
europepmc   +4 more sources