Results 31 to 40 of about 2,197 (174)

Identification and Genomic Analysis of the First Salmonella typhimurium Monophasic Variant 1,4,[5],12:i:- Isolate Harbouring a Chromosomally Integrated bla_NDM-5. [PDF]

Microb Biotechnol
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Zeng S, Guo W, Lin C, Peng L, Song J.
europepmc   +2 more sources

Genomic characterization of a carbapenem-resistant Citrobacter freundii clinical isolate from China carrying blaNDM-5 on a novel IncC-IncFIB-IncX3 plasmid

Journal of Global Antimicrobial Resistance
: Objectives: Citrobacter freundii is one of the important pathogens that can cause nosocomial infections. The advent of carbapenem-resistant C. freundii complicates clinical treatment.
Hao Guo, Lirong Li, Yawen Zhang, Fang He
doaj   +2 more sources

Characterization of the IncX3 Plasmid Producing blaNDM–7 From Klebsiella pneumoniae ST34 [PDF]

Frontiers in Microbiology, 2020
Carbapenemase-producing Klebsiella pneumoniae has been a major clinical threat worldwide because therapeutic options are limited. Although New Delhi metallo-β-lactamase (NDM) is an important carbapenemase responsible for carbapenem resistance, it is uncommon in carbapenemase-producing K. pneumoniae in China. In this study, we described strain HZW25, an
Qiong Chen, Jiawei Zhou, Shenghai Wu, Yunxing Yang, Daojun Yu, Xianjun Wang, Min Wu   +6 more
openaire   +3 more sources

Transmission of global clones of NDM-producing Enterobacterales and interspecies spread of IncX3 plasmid harbouring blaNDM-5 in Tokyo

Journal of Global Antimicrobial Resistance
Objective: The aim of this study is to characterise the molecular characteristics of NDM-producing Enterobacterales, which have been on the increase in recent years in Japan, where IMP-producing bacteria are dominant among carbapenemase-producing ...
Sohei Harada, Kotaro Aoki, Yusuke Nomura, Yuki Ohama, Hideki Araoka, Brian Hayama, Takayuki Sakurai, Akihiro Ueda, Yoshikazu Ishii, Takeya Tsutsumi   +9 more
doaj   +3 more sources

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High-Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa. [PDF]

Microbiologyopen
Graphical presentation of rectal carriage of carbapenem‐resistant Klebsiella pneumoniae, highlighting ST307 high‐risk clone and IncX3 plasmid‐associated blaOXA‐181. This study highlights the threat linked to horizontal gene transfer of AMR genes by epidemic plasmids from Klebsiella pneumoniae high‐risk clones to other bacterial species.
Salvador-Oke KT, Pitout J, Peirano G, Strydom KA, Kingsburgh C, Ehlers M, Kock M.   +6 more
europepmc   +2 more sources

OXA-181 transmission confounded by a stable IncX3 plasmid

Abstract OXA-48-like carbapenemases have been historically rare, however steady increases both locally and globally have warranted further investigation into their spread. Here we present the largest genomic analysis of bla OXA-181 -producing bacteria in Australia ...
Lee TSE, Nguyen L, Forde BM, Maidment T, Ye S, Henderson A, Playford EG, Runnegar N, Henderson B, Watson C, Lindsay M, Bursle E, Douglas J, Hume J, Paterson DL, Kidd T, Graves B, Hume A, Hall MB, Schembri MA, Beatson SA, Harris PN, Roberts LW.   +22 more
europepmc   +2 more sources

Emergence of a High-Risk Klebsiella michiganensis Clone Disseminating Carbapenemase Genes

Frontiers in Microbiology, 2022
Klebsiella michiganensis is emerging as an important human pathogen of concern especially strains with plasmid-mediated carbapenemase genes. The IncX3-blaNDM-5 plasmid has been described as the primary vector for blaNDM-5 dissemination.
Isaac Prah, Isaac Prah, Yoko Nukui, Yoko Nukui, Shoji Yamaoka, Ryoichi Saito, Ryoichi Saito   +6 more
doaj   +1 more source

Table_4_In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales.xlsx

, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhixiong Zheng (13757638), Shengni Hua (417714), Zhijian Yu (778086), Zhengrong Zhang (838088), Xiaobin Li (750526), Mubiao Liu (13757644), Xiaosan Feng (13757641), Ting Luan (10533029), Lile Shi (13757635), Qiuping Lin (3091146)   +9 more
core   +1 more source

DataSheet_1_In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales.docx

, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhixiong Zheng (13757638), Shengni Hua (417714), Zhijian Yu (778086), Zhengrong Zhang (838088), Xiaobin Li (750526), Mubiao Liu (13757644), Xiaosan Feng (13757641), Ting Luan (10533029), Lile Shi (13757635), Qiuping Lin (3091146)   +9 more
core   +1 more source

Table_2_In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales.xlsx

, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhixiong Zheng (13757638), Shengni Hua (417714), Zhijian Yu (778086), Zhengrong Zhang (838088), Xiaobin Li (750526), Mubiao Liu (13757644), Xiaosan Feng (13757641), Ting Luan (10533029), Lile Shi (13757635), Qiuping Lin (3091146)   +9 more
core   +1 more source