Characterization of blaNDM-19-producing IncX3 plasmid isolated from carbapenem-resistant Escherichia coli and Klebsiellapneumoniae [PDF]
Heliyon, 2023 The increase in the prevalence of carbapenem-producing Enterobacterales (CPE) is a major threat, with the New Delhi metallo-β-lactamase (NDM) enzyme-producing CPEs being one of the major causative agents of healthcare settings infections.
Sima Tokajian +2 more
exaly +7 more sources
Temperature-Regulated IncX3 Plasmid Characteristics and the Role of Plasmid-Encoded H-NS in Thermoregulation [PDF]
Frontiers in Microbiology, 2022 Carbapenem-resistant Enterobacteriaceae (CRE) are a critical public health problem worldwide. Globally, IncX3-type plasmids have emerged as the predominant vehicles carrying the metallo-β-lactamase gene blaNDM. Although blaNDM-bearing IncX3 plasmids have
Liu Baomo +5 more
doaj +7 more sources
VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of bla NDM-5 in zoonotic bacteria [PDF]
Nature CommunicationsIncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, bla NDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in animals, the ...
Tengfei Ma +13 more
doaj +14 more sources
Molecular Characterization of blaNDM-Carrying IncX3 Plasmids: blaNDM-16b Likely Emerged from a Mutation of blaNDM-5 on IncX3 Plasmid. [PDF]
Microbiology Spectrum, 2022 Dissemination of blaNDM, which is carried on the IncX3 plasmid, among Enterobacterales has been reported worldwide. In particular, blaNDM-5-carrying IncX3 plasmids can spread among several hosts, facilitating their dissemination.
Yoshikazu Ishii +2 more
exaly +4 more sources
Global prevalence, characteristics, and future prospects of IncX3 plasmids: A review
Frontiers in Microbiology, 2022 IncX3 plasmids are narrow host range plasmids mostly found in Enterobacteriaceae with great conjugation ability, high stability, no fitness cost, and the ability to improve biofilm formation in their bacterial hosts.
Haoyu Ge, Ruyan Chen, Xiaobing Guo
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Genotypic and Phenotypic Characterization of IncX3 Plasmid Carrying blaNDM-7 in Escherichia coli Sequence Type 167 Isolated From a Patient With Urinary Tract Infection [PDF]
Frontiers in Microbiology, 2018 Infections due to New Delhi metallo-beta lactamase (NDM)-7-producing Escherichia coli are infrequent and sporadic. In this study, we report one case of recurrent urinary tract infection caused by blaNDM-7-producing E. coli belonging to phylogenetic group
Yingying Hao +3 more
doaj +4 more sources
Case Report of blaNDM-7-Harboring IncX3 Plasmid in ST196 Klebsiella quasipneumoniae in China
Infection and Drug Resistance, 2022 Lin Sun,1,2,* Guiling Li,3,4,* Nan Meng,1 Zhenyu Wang,1 Hanyun Wang,1 Jing Wang,1,2 Xinan Jiao1,2 1Jiangsu Key Laboratory of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses ...
Xin'an Jiao
exaly +3 more sources
Plasmid-resolved genomics and machine learning-assisted profiling reveal Enterobacter soli as an overlooked host of a blaNDM-1-bearing IncX3 plasmid [PDF]
Frontiers in MicrobiologyBackgroundPlasmid-mediated carbapenem resistance is a major public health concern, yet the role of under-characterized Enterobacter species in carrying clinically important resistance plasmids remains insufficiently defined.
Yao Li +8 more
doaj +2 more sources
Genotypic and Phenotypic Characterization of blaNDM–7-Harboring IncX3 Plasmid in a ST11 Klebsiella pneumoniae Isolated From a Pediatric Patient in China [PDF]
Frontiers in Microbiology, 2020 NDM-7, a variant of New Delhi metallo-beta-lactamases (NDM), has the highest carbapenem-hydrolyzing activity. NDM-7-producing enterobacteria have been reported in many countries.
Chunhong Shao +4 more
doaj +2 more sources
Cross-species transmission of blaNDM-5-IncX3 plasmids: molecular mechanisms and One Health-based strategies for CREC control [PDF]
Frontiers in Cellular and Infection MicrobiologyCarbapenem-resistant Escherichia coli (CREC) has emerged as a critical global health concern, particularly strains carrying the blaNDM-5-IncX3 plasmid.
Benjin Xu +9 more
doaj +2 more sources