Results 31 to 40 of about 127,927 (175)

Dissemination of bla NDM-5 gene via an IncX3-type plasmid among non-clonal Escherichia coli in China [PDF]

Antimicrobial Resistance & Infection Control, 2018
Background The emergence and spread of New Delhi metallo-β-lactamase-producing Enterobacteriaceae has been a serious challenge to manage in the clinic due to its rapid dissemination of multi-drug resistance worldwide.
Yunsong Yu, Ying Fu, Xi Li, Danyan Huang, Mengyuan Shen, Xiaoxing Du, Qingfeng Hu, Yonglie Zhou, Dairong Wang   +8 more
core   +4 more sources

Characterization of the IncX3 Plasmid Producing bla _NDM-7 From Klebsiella pneumoniae ST34. [PDF]

Front Microbiol, 2020
Carbapenemase-producing Klebsiella pneumoniae has been a major clinical threat worldwide because therapeutic options are limited. Although New Delhi metallo-β-lactamase (NDM) is an important carbapenemase responsible for carbapenem resistance, it is uncommon in carbapenemase-producing K. pneumoniae in China. In this study, we described strain HZW25, an
Chen Q, Zhou J, Wu S, Yang Y, Yu D, Wang X, Wu M.   +6 more
europepmc   +5 more sources

First report of blaOXA-181-carrying IncX3 plasmids in multidrug-resistant Enterobacter hormaechei and Serratia nevei recovered from canine and feline opportunistic infections [PDF]

Microbiology Spectrum
Whole-genome sequence analysis of six Enterobacter hormaechei and two Serratia nevei strains, using a hybrid assembly of Illumina and Oxford Nanopore Technologies sequencing, revealed the presence of the epidemic blaOXA-181-carrying IncX3 plasmids co ...
Chavin Leelapsawas, Parinya Sroithongkham, Sunchai Payungporn, Pattaraporn Nimsamer, Jitrapa Yindee, Alexandra Collaud, Vincent Perreten, Pattrarat Chanchaithong   +7 more
doaj   +3 more sources

First Report of bla_NDM-1 Bearing IncX3 Plasmid in Clinically Isolated ST11 Klebsiella pneumoniae from Pakistan. [PDF]

Microorganisms, 2021
The New Delhi Metallo-β-lactamase (NDM) is among the most threatening forms of carbapenemases produced by K. pneumoniae, well-known to cause severe worldwide infections. The molecular epidemiology of blaNDM-1-harboring K.
Bilal H, Zhang G, Rehman T, Han J, Khan S, Shafiq M, Yang X, Yan Z, Yang X.   +8 more
europepmc   +2 more sources

Identification and Genomic Analysis of the First Salmonella typhimurium Monophasic Variant 1,4,[5],12:i:- Isolate Harbouring a Chromosomally Integrated bla_NDM-5. [PDF]

Microb Biotechnol
This study reports the first clinical isolate of the monophasic variant of Salmonella typhimurium (serotype 1,4,[5],12:i:‐) ST34 harbouring a chromosomally integrated blaNDM‐5. The ~11 kb resistance region is flanked by two directly oriented IS26 elements, forming an IS26‐composite transposon.
Zeng S, Guo W, Lin C, Peng L, Song J.
europepmc   +2 more sources

Emergence of a High-Risk Klebsiella michiganensis Clone Disseminating Carbapenemase Genes

Frontiers in Microbiology, 2022
Klebsiella michiganensis is emerging as an important human pathogen of concern especially strains with plasmid-mediated carbapenemase genes. The IncX3-blaNDM-5 plasmid has been described as the primary vector for blaNDM-5 dissemination.
Isaac Prah, Isaac Prah, Yoko Nukui, Yoko Nukui, Shoji Yamaoka, Ryoichi Saito, Ryoichi Saito   +6 more
doaj   +1 more source

Transmission of global clones of NDM-producing Enterobacterales and interspecies spread of IncX3 plasmid harbouring blaNDM-5 in Tokyo

Journal of Global Antimicrobial Resistance
Objective: The aim of this study is to characterise the molecular characteristics of NDM-producing Enterobacterales, which have been on the increase in recent years in Japan, where IMP-producing bacteria are dominant among carbapenemase-producing ...
Sohei Harada, Kotaro Aoki, Yusuke Nomura, Yuki Ohama, Hideki Araoka, Brian Hayama, Takayuki Sakurai, Akihiro Ueda, Yoshikazu Ishii, Takeya Tsutsumi   +9 more
doaj   +3 more sources

Emergence of an IncX3 plasmid co-harbouring the carbapenemase genes bla_NDM-5 and bla_OXA-181. [PDF]

JAC Antimicrob Resist
Abstract Background The spread of transmissible plasmids with carbapenemase genes has contributed to a global increase in carbapenemase-producing Enterobacterales over the past two decades, with blaNDM and blaOXA among the most prevalent carbapenemase genes.
Zuo H, Sugawara Y, Kondo K, Kayama S, Kawakami S, Uechi K, Nakano A, Yahara K, Sugai M.   +8 more
europepmc   +3 more sources

Emergence of oxacillinase-181 carbapenemase-producing diarrheagenic Escherichia coli in Ghana

Emerging Microbes and Infections, 2021
The emergence and spread of carbapenemase-producing bacteria are serious threats to public health. We characterized two OXA-181-producing Escherichia coli isolates from pediatric patients with diarrhea from Ghana.
Isaac Prah, Alafate Ayibieke, Samiratu Mahazu, Chihiro Tani Sassa, Takaya Hayashi, Shoji Yamaoka, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito   +9 more
doaj   +1 more source

Characterization of Klebsiella pneumoniae carrying the blaNDM-1 gene in IncX3 plasmids and the rare In1765 in an IncFIB-IncHI1B plasmid

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundToday, the blaNDM gene is widely distributed on several plasmids from a variety of Gram-negative bacteria, primarily in transposons and gene cassettes within their multidrug-resistant (MDR) regions. This has led to the global dissemination of the blaNDM gene.MethodsThe determination of class A beta-lactamase, class B and D carbapenemases was ...
Liman Ma, Liman Ma, Ying Qu, Wenji Wang, Wenji Wang, Dongguo Wang, Dongguo Wang   +6 more
openaire   +3 more sources