Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 [PDF]
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Feng, Y +5 more
core +1 more source
Abstract Antimicrobial agents are a critical component of modern healthcare systems, fulfilling a core function in patient care and improving individual patient outcomes and consequently overall public health. However, the efficacy of antimicrobial interventions is being consistently eroded by the emergence and dissemination of various antimicrobial ...
Richard Harding‐Crooks +3 more
wiley +1 more source
Plasmid-mediated novel blaNDM-17 gene encoding a Carbapenemase with enhanced activity in a sequence type 48 Escherichia coli strain [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) have spread worldwide, leaving very few treatment options available. New Delhi metallo-beta-lactamase (NDM) is the main carbapenemase mediating CRE resistance and is of increasing concern.
Li, Jiyun +9 more
core +2 more sources
The emergence and spread of carbapenem resistance in Gram‐negative bacilli such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa through the production of carbapenemases is a global phenomenon. It threatens patient care and leads to therapeutic impasses.
Boukaré Kaboré +11 more
wiley +1 more source
Dissection of Highly Prevalent qnrS1-Carrying IncX Plasmid Types in Commensal Escherichia coli from German Food and Livestock [PDF]
Plasmids are mobile genetic elements, contributing to the spread of resistance determinants by horizontal gene transfer. Plasmid-mediated quinolone resistances (PMQRs) are important determinants able to decrease the antimicrobial susceptibility of ...
Hammerl, Jens André +5 more
core +1 more source
Abstract Aims Spread of carbapenem‐resistant Enterobacterales have become a global problem. We characterized extended‐spectrum β‐lactamase (ESBL)‐producing Enterobacterales from urinary tract infections cases from Allied Hospital Faisalabad, Pakistan. Methods and Results Eleven (22%, 11/50) ESBL‐producing Enterobacterales (Escherichia coli; n = 10 and ...
Mashkoor Mohsin +5 more
wiley +1 more source
Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying blaKPC-2 in a Klebsiella pneumoniae [PDF]
The IncX family of plasmids has recently been expanded to include at least four subtypes, IncX1-IncX4. The revised classification provides an opportunity for improving our understanding of the sequence diversity of the IncX plasmids and the resistance ...
Chan, JFW +7 more
core +1 more source
In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhijian Yu +9 more
doaj +1 more source
Resistance to carbapenems in non-typhoidal Salmonella enterica serovars from humans, animals and food [PDF]
Non-typhoidal serovars of Salmonella enterica (NTS) are a leading cause of food-borne disease in animals and humans worldwide. Like other zoonotic bacteria, NTS have the potential to act as reservoirs and vehicles for the transmission of antimicrobial ...
Fernández, J. +2 more
core +3 more sources
Mechanisms involved in acquisition of bla
Copyright © 2016, American Society for Microbiology. All Rights Reserved. blaNDM genes confer carbapenem resistance and have been identified on transferable plasmids belonging to different incompatibility (Inc) groups.
Alikhan, NF +12 more
core +5 more sources

