Results 31 to 40 of about 22,786,144 (157)
Emergence of carbapenem-resistant Klebsiella pneumoniae harbouring bla OXA-48-like genes in China [PDF]
, 2021 Klebsiella pneumoniae strains carrying OXA-48-like carbapenemases are increasingly prevalent across the globe. There is thus an urgent need to better understand the mechanisms that underpin the dissemination of bla OXA-48-like carbapenemases. To this end,
Yan, Rushuang +25 more
core +1 more source
Detection of OXA-181-producing Pseudomonas aeruginosa in Germany
International Journal of Medical Microbiology, 2022 Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: Carbapenemase detection was performed by using several phenotypic tests such as the modified Hodge test, a ...
Jennifer Schauer +4 more
doaj +1 more source
Oxa-TriQuinoline: A New Entry to Aza-Oxa-Crown Architectures [PDF]
, 2023 A new 15-membered-macrocyclic molecular entity, oxa-TriQuinoline (o-TQ), was designed and synthesized. In o-TQ, three oxygen atoms were joined onto three quinoline units at the 2- and 8-positions in a head-to-tail fashion via three-fold SNAr reactions ...
Naoya, Kumagai, Toi, Kobayashi
core +2 more sources
Borylcyclopropanes: Synthetic Strategies and Applications
Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +2 more sources
, 2018 The class D carbapenemase OXA-48 was first detected in 2001 from a carbapenem-resistant Klebsiella pneumoniae isolate in Istanbul, Turkey [1]. The variant OXA-181, which differs from OXA-48 by four amino acids, was isolated later in India in 2007 from ...
Christel Dagher +9 more
core +1 more source
Characterization of OXA-181, a Carbapenem-Hydrolyzing Class D β-Lactamase from Klebsiella pneumoniae
, 2011 Klebsiella pneumoniae KP3 was isolated from a patient transferred from India to the Sultanate of Oman. K. pneumoniae KP3 was resistant to all β-lactams, including carbapenems, and expressed the carbapenem-hydrolyzing β-
Laurent Poirel +5 more
core +1 more source
Investigation Of Bla(Oxa-48)-Like Genes İn Carbapenemase Producing Klebsiella Spp. Isolates [PDF]
, 2019 The emergence and spread of multi-drug-resistant (MDR), extended-spectrum beta-lactamase (ESBL) producing carbapenem-resistant members of Enterobacteriaceae family has become a worldwide health problem.
Elmas Pinar Kahraman +7 more
core +1 more source
Journal of Infection in Developing CountriesIntroduction: Carbapenemase-producing Enterobacterales (CPE) pose a serious threat to public health worldwide and are a challenge for clinicians due to the limited antimicrobial options available.
Pearl Ntshonga +4 more
doaj +1 more source
Synthesis of a Novel, Highly Symmetric Bis-Oxa-Bridged Compound
, 2016 A highly oxygenated, novel pentacyclic bis-oxa-bridged compound 8 was synthesized with remarkable efficiency starting from readily available tetrachloro-5,5-dimethoxyclopentadiene and 1,4-cyclohexadiene in three steps.
Jyotirmayee Dash (1616845) +1 more
core +2 more sources
Emerging Infectious Diseases, 2018 Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the United States. We performed phenotypic and genotypic characterization of 30 Enterobacteriaceae producing OXA-48–like carbapenemases that were recovered from patients during 2010 ...
Joseph D. Lutgring +9 more
doaj +1 more source