Results 51 to 60 of about 22,786,144 (157)

Unveiling the Emergence and Genetic Diversity of OXA-48-like Carbapenemase Variants in Shewanella xiamenensis

Microorganisms, 2023
An increase in the carbapenem-hydrolyzing capacity of class D β-lactamase has been observed in strains of multiple species, posing a significant challenge to the control of antibiotic resistance.
Xueqi Jiang, Beibei Miao, Xiaofei Zhao, Xuemei Bai, Min Yuan, Xia Chen, Xinyi Gong, Zeliang Liu, Jie Li, Shuang Meng, Xiao Han, Juan Li   +11 more
doaj   +1 more source

Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li, Henghui Deng, Shiwei Yu, Jiawei Huang, Zehong Chen, Dawei Zhao, Chaoqun Zhang   +6 more
wiley   +1 more source

Development of a Novel Real-Time PCR Assay with High-Resolution Melt Analysis To Detect and Differentiate OXA-48-Like β-Lactamases in Carbapenem-Resistant Enterobacteriaceae [PDF]

, 2015
The rapid global spread of carbapenem-resistant Enterobacteriaceae (CRE) poses an urgent threat to public health. More than 250 class D β-lactamases (OXAs) have been described in recent years, with variations in hydrolytic activity for β-lactams.
Humphries, Romney M, Hemarajata, Peera, Yang, Shangxin, Hindler, Janet A   +3 more
core   +1 more source

Possible Dissemination of Escherichia coli Sequence Type 410 Closely Related to B4/H24RxC in Ghana

Frontiers in Microbiology, 2021
Extra-intestinal pathogenic Escherichia coli (ExPEC) is one of the world’s leading causes of bloodstream infections with high mortality. Sequence type 410 (ST410) is an emerging ExPEC clone resistant to a wide range of antibiotics.
Samiratu Mahazu, Samiratu Mahazu, Isaac Prah, Isaac Prah, Alafate Ayibieke, Wakana Sato, Takaya Hayashi, Toshihiko Suzuki, Shiroh Iwanaga, Anthony Ablordey, Ryoichi Saito   +10 more
doaj   +1 more source

A Four‐Center Study on the Activity of Aztreonam and Aztreonam‐Avibactam Combination Against Clinical Isolates of Gram‐Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β‐Lactamases

APMIS, Volume 134, Issue 9, September 2026.
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Gizem İnce Ceviz, Hasan Cenk Mirza, Aylin Üsküdar Güçlü, Özlem Öğüç Şanlı, Özlem Kurt Azap, Banu Sancak, Elvan Hortaç İştar, Ahmet Başustaoğlu   +7 more
wiley   +1 more source

First Report of OXA-181-Producing Klebsiella pneumoniae in China

Infection and Drug Resistance, 2020
Congcong Liu,1 Yinfei Fang,2 Yu Zeng,1 Jiayue Lu,1 Qiaoling Sun,1 Hongwei Zhou,1 Zhangqi Shen,3 Gongxiang Chen1 1Department of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang, Hangzhou, People’s ...
Liu C, Fang Y, Zeng Y, Lu J, Sun Q, Zhou H, Shen Z, Chen G   +7 more
doaj  

Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga, Giusy L. Fratello, Alexander T. Apostle, Roberto Orru, David M. Barber, Silvia Gazzola   +5 more
wiley   +1 more source

Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]

, 2017
Objectives Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum cephalosporins.
Oueslati, Saoussen, Nordmann, Patrice, Poirel, Laurent   +2 more
core  

Repurposing a Lipid Droplet‐Associated Algal Protein as a Biosensor for Phosphatidic Acid

Advanced Sensor Research, Volume 5, Issue 8, August 2026.
The DTH1 lipid binding domain (DTH1LBD) binds to lipid membranes containing phosphatidic acid (PA). Its N‐terminal amphipathic helices are sufficient for this association and, when labeled with solvatochromic fluorophores, can serve as in vitro PA biosensors.
Bilge Ercan, Nian Kee Tan, Julia Lin, Jingyao You, Stephen M. Butler, Katrina A. Jolliffe   +5 more
wiley   +1 more source

DataSheet_1_In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales.docx

, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhixiong Zheng (13757638), Shengni Hua (417714), Zhijian Yu (778086), Zhengrong Zhang (838088), Xiaobin Li (750526), Mubiao Liu (13757644), Xiaosan Feng (13757641), Ting Luan (10533029), Lile Shi (13757635), Qiuping Lin (3091146)   +9 more
core   +1 more source