Resistance to colistin associated with a single amino acid change in protein PmrB among Klebsiella pneumoniae isolates of worldwide Origin [PDF]
A series of colistin-resistant Klebsiella pneumoniae isolates recovered from different countries was investigated in order to evaluate the involvement of the PmrA/PmrB two-component system in this resistance. Six isolates possessed a mutated PmrB protein,
Brink, Adrian +5 more
core +1 more source
Emergence of <i>Salmonella enterica</i> carrying <i>bla</i> <sub>OXA-181</sub> carbapenemase gene, Italy, 2021 to 2024. [PDF]
Between 2021 and 2024, we detected carbapenemase gene blaOXA-181 in 16 of 11,398 Salmonella enterica (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer.
Bolzoni L +19 more
europepmc +4 more sources
Rapid detection of carbapenemase-producing Enterobacteriaceae. [PDF]
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem.
Dortet, L, Nordmann, P, Poirel, L
core +1 more source
Detection of OXA-181/OXA-48 carbapenemase producing Enterobacteriaceae in Bangladesh
Carbapenem resistant Enterobacteriaceae (CRE) is becoming a major public health concern globally. Detection of carbapenem hydrolyzing enzyme carbapenemase in Enterobacteriaceae is important to institute appropriate therapy and to initiate preventive measures.
Rehana Khatun, S.M. Shamsuzzaman
openaire +3 more sources
Shedding of OXA-181 carbapenemase-producing Escherichia coli from companion animals after hospitalisation in Switzerland: an outbreak in 2018. [PDF]
Background Carbapenem-resistant Enterobacteriaceae pose a serious threat to public health worldwide, and the role of companion animals as a reservoir is still unclear. Aims This 4-month prospective observational study evaluated carriage of ...
Nigg A +9 more
europepmc +6 more sources
The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Brink AJ +5 more
core +2 more sources
Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the United States. We performed phenotypic and genotypic characterization of 30 Enterobacteriaceae producing OXA-48–like carbapenemases that were recovered from patients during 2010 ...
Joseph D. Lutgring +9 more
doaj +1 more source
blaOXA-181–positiveKlebsiella pneumoniae, Singapore
To the Editor: Nordmann et al. (1) raised concern over the global spread of carbapenemase-producing Enterobacteriaceae. In their article, they called attention to the oxacillinase-48 (OXA-48) type carbapenemases because bacteria that produce these enzymes do not have a distinctive antimicrobial drug susceptibility profile, and there is less awareness ...
Tse H. Koh +7 more
openaire +2 more sources
Rapidec Carba NP Test for Rapid Detection of Carbapenemase Producers [PDF]
Performances of the Rapidec Carba NP test (bioMérieux) were evaluated for detection of all types of carbapenemases in Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa.
Nordmann, Patrice, Poirel, Laurent
core +1 more source
Cyclic Boronates Inhibit All Classes of β-Lactamase [PDF]
β-Lactamase-mediated resistance is a growing threat to the continued use of β-lactam antibiotics. The use of the β-lactam-based serine-β-lactamase (SBL) inhibitors clavulanic acid, sulbactam, tazobactam, and, more recently, the non-β-lactam inhibitor ...
Brem, J +11 more
core +5 more sources

