Results 1 to 10 of about 3,195 (172)

Epidemiological Characteristics of OXA-232-Producing Carbapenem-Resistant Klebsiella pneumoniae Strains Isolated during Nosocomial Clonal Spread Associated with Environmental Colonization [PDF]

Microbiology Spectrum, 2022
Here, a program was designed to surveil the colonization and associated infection of OXA-232-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) (OXA-232-CRKP) in an intensive care unit (ICU) and to describe the epidemiological characteristics ...
Xinhong Han, Ying Chen, Junxin Zhou, Qiucheng Shi, Yan Jiang, Xueqing Wu, Jingjing Quan, Huangdu Hu, Qian Wang, Yunsong Yu, Ying Fu   +10 more
doaj   +6 more sources

Outbreak of OXA-232-producing carbapenem-resistant Klebsiella pneumoniae ST15 in a Chinese teaching hospital: a molecular epidemiological study [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
Background and AimsThe incidence of OXA-232-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) has been on the rise in China over the past five years, potentially leading to nosocomial epidemics.
Xiaoyan Wu, Xiangchen Li, Junjie Yu, Mengli Shen, Chenliang Fan, Yewei Lu, Junshun Gao, Xiaosi Li, Hongsheng Li   +8 more
doaj   +7 more sources

Increased clonal dissemination of OXA-232-producing ST15 Klebsiella pneumoniae in Zhejiang, China from 2018 to 2021 [PDF]

Infectious Diseases of Poverty, 2023
Background OXA-232-producing Klebsiella pneumoniae was first identified in China in 2016, and its clonal transmission was reported in 2019. However, there are no prevalence and genotypic surveillance data available for OXA-232 in China.
Yanyan Zhang, Xuemei Yang, Congcong Liu, Ling Huang, Lingbin Shu, Qiaoling Sun, Hongwei Zhou, Yonglu Huang, Chang Cai, Xiaoyan Wu, Sheng Chen, Rong Zhang   +11 more
doaj   +4 more sources

Polyclonal Dissemination of OXA-232 Carbapenemase–Producing Klebsiella pneumoniae, France, 2013–2021 [PDF]

Emerging Infectious Diseases, 2022
During 2013–2021, increased prevalence of oxacillinase 232–producing Enterobacterales was observed in France, mostly driven by its emergence in Klebsiella pneumoniae. Whole-genome sequencing identified that oxacillinase 232–producing K.
Cecile Emeraud, Aurélien Birer, Delphine Girlich, Agnès B. Jousset, Elodie Creton, Thierry Naas, Rémy A. Bonnin, Laurent Dortet   +7 more
doaj   +4 more sources

Nosocomial spread of OXA-232-producing Klebsiella pneumoniae ST15 in a teaching hospital, Shanghai, China [PDF]

BMC Microbiology, 2019
Background The spread and outbreak of Enterobacteriaceae producing OXA-48-like carbapenemases have become more and more prevalent in China. Results A total of 62 non-duplicated OXA-232-producing K.
Xin Li, Wei Ma, Qin Qin, Shanrong Liu, Liyan Ye, Jiyong Yang, Boan Li   +6 more
doaj   +5 more sources

Whole genome sequencing of OXA-232-producing wzi93-KL112-O1 carbapenem-resistant Klebsiella pneumoniae in human bloodstream infection co-harboring chromosomal ISEcp1-based blaCTX-M-15 and one rmpA2-associated virulence plasmid [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
ObjectivesTo characterize one OXA-232-producing wzi93-KL112-O1 carbapenem-resistant Klebsiella pneumoniae (CRKP) co-harboring chromosomal blaCTX-M-15 and one rmpA2-associated virulence plasmid.MethodsMinimum inhibitory concentrations (MICs) were measured
Chongmei Tian, Mengyu Xing, Yaping Zhao, Xueyu Fan, Yongfeng Bai, Liping Fu, Siwei Wang   +6 more
doaj   +4 more sources

Isolation of Hv-CRKP with co-production of three carbapenemases (blaKPC, blaOXA-181 or OXA-232, and blaNDM-1) and a virulence plasmid: a study from a Chinese tertiary hospital [PDF]

Frontiers in Microbiology, 2023
BackgroundThe worldwide dissemination of K. pneumoniae isolates is a significant public health concern, as these organisms possess a unique capacity to acquire genetic elements encoding both resistance and hypervirulence.
Ping Li, Ping Li, Ping Li, Wan-ying Luo, Wan-ying Luo, Tian-Xin Xiang, Ting-xiu Peng, Ting-xiu Peng, Shuai Luo, Shuai Luo, Zhi-yong He, Zhi-yong He, Wenjian Liao, Dan-Dan Wei, Dan-Dan Wei, Peng Liu, La-gen Wan, Wei Zhang, Wei Zhang, Yang Liu, Yang Liu   +20 more
doaj   +4 more sources

Outer membrane vesicles mediating horizontal transfer of the epidemic blaOXA-232 carbapenemase gene among Enterobacterales [PDF]

Emerging Microbes and Infections
OXA-232 is one of the most common OXA-48-like carbapenemase derivatives and is widely disseminated in nosocomial settings across countries. The blaOXA-232 gene is located on a 6-kb non-conjugative ColKP3-type plasmid, while the dissemination of blaOXA ...
Zhen Shen, Juanxiu Qin, Guoxiu Xiang, Tianchi Chen, Nadira Nurxat, Qianqian Gao, Chen Wang, Haomin Zhang, Yao Liu, Min Li   +9 more
doaj   +4 more sources

A Nationwide Genomic Study of Clinical Klebsiella pneumoniae Carrying blaOXA-232 and rmtF in China [PDF]

Microbiology Spectrum, 2023
OXA-232 carbapenemase is becoming a threat in China due to its high prevalence, mortality, and limited treatment options. However, little information is available on the impact of OXA-232-producing Klebsiella pneumoniae in China.
Siquan Shen, Renru Han, Dandan Yin, Bo Jiang, Li Ding, Yan Guo, Shi Wu, Chuning Wang, Hong Zhang, Fupin Hu   +9 more
doaj   +2 more sources

Emergence of bla_NDM-5 and bla_OXA-232 Positive Colistin- and Carbapenem-Resistant Klebsiella pneumoniae in a Bulgarian Hospital [PDF]

Antibiotics
The rapid spread of carbapenemase-producing strains has led to increased levels of resistance among Gram-negative bacteria, especially enterobacteria. The current study aimed to collect and genetically characterize the colistin- and carbapenem-resistant ...
Rumyana Markovska, Petya Stankova, Georgi Popivanov, Ivanka Gergova, Kalina Mihova, Ventsislav Mutafchiyski, Lyudmila Boyanova   +6 more
doaj   +2 more sources