Results 11 to 20 of about 3,195 (172)

The Characterization of OXA-232 Carbapenemase-Producing ST437 Klebsiella pneumoniae in China [PDF]

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Carbapenem-resistant Klebsiella pneumoniae (CRKP) was epidemic around the world and become a global threat to public health. The most important carbapenem-resistant mechanism is producing carbapenemases, especially Klebsiella pneumoniae carbapenemase ...
Xingbei Weng, Qiucheng Shi, Sheng Wang, Yubo Shi, Dinghe Sun, Yunsong Yu   +5 more
doaj   +5 more sources

Emergence and genomics of OXA-232-producing Klebsiella pneumoniae in a hospital in Yancheng, China

Journal of Global Antimicrobial Resistance, 2021
: Objectives: The aims of this study were to infer the phylogenetic relationship of OXA-232-producing Klebsiella pneumoniae (OXA232Kp) strains collected from a Chinese hospital and to determine the composition and genetic background of antimicrobial ...
Zhichen Zhu, Haifeng Huang, Yumei Xu, Min Wang, Jinnan Lv, Linlin Xu, Chunlei Shi, Ya Xu, Ruifu Yang, Liang Chen, Hong Du   +10 more
doaj   +5 more sources

Different effects of plasmids harboring blaOXA-232 between major and minor clones in Klebsiella pneumoniae [PDF]

Microbiology Spectrum
This study investigated the differing impact of introducing the globally reported blaOXA-232-harboring ColE-type plasmid on the plasmid stability, competitiveness, virulence, and gene expression of Klebsiella pneumoniae transconjugants from major high ...
Yun Young Cho, Hyun Woo Kim, Si Ho Kim, Yu Mi Wi, Kwan Soo Ko   +4 more
doaj   +4 more sources

Clonal Dissemination of OXA-232 Carbapenemase-Producing Klebsiella pneumoniae in Neonates. [PDF]

Antimicrob Agents Chemother, 2017
ABSTRACT Five OXA-232 carbapenemase-producing Klebsiella pneumoniae isolates, belonging to the pandemic clone sequence type 15 (ST15), were isolated from neonates and coproduced bla CTX-M-15 and bla SHV-1 genes.
Yin D, Dong D, Li K, Zhang L, Liang J, Yang Y, Wu N, Bao Y, Wang C, Hu F.   +9 more
europepmc   +5 more sources

Co-Production of NDM-1 and OXA-232 by Klebsiella pneumoniae [PDF]

Emerging Infectious Diseases, 2014
To the Editor: New Delhi metallo-β-lactamase 1 (NDM-1) and OXA-48-group β-lactamase have been increasingly reported as carbapenemases responsible for carbapenem resistance in Enterobacteriaceae worldwide (1). However, in the United States, Klebsiella pneumoniae carbapenemase (KPC)–type β-lactamase is the most common carbapenemase among ...
Yohei Doi, Jessica A. O’Hara, James F. Lando, Ashley M. Querry, Bethany M. Townsend, Anthony W. Pasculle, Carlene A. Muto   +6 more
doaj   +3 more sources

High-Level Carbapenem Resistance in OXA-232-Producing Raoultella ornithinolytica Triggered by Ertapenem Therapy. [PDF]

Antimicrob Agents Chemother, 2019
OXA-232 is an OXA-48-group class D β-lactamase that hydrolyzes expanded-spectrum cephalosporins and carbapenems at low levels. Clinical strains producing OXA-232 are sometimes susceptible to carbapenems, making it difficult to identify them in the clinical microbiology laboratory.
Iovleva A, Mettus RT, McElheny CL, Griffith MP, Mustapha MM, Pasculle AW, Shields RK, Cooper VS, Doi Y.   +8 more
europepmc   +5 more sources

Emergence of an MDR Klebsiella pneumoniae ST231 producing OXA-232 and RmtF in Switzerland [PDF]

Journal of Antimicrobial Chemotherapy, 2017
The increasing incidence of carbapenem-resistant Klebsiella pneumoniae is a major challenge to public health. Despite the fact that the prevalence of carbapenemases among carbapenem-resistant K.
Bassi, Cécile, Lienhard, Reto, Mancini, Stefano, Nordmann, Patrice, Poirel, Laurent, Tritten, Marie-Lise   +5 more
core   +6 more sources

Rapidly disseminating bla OXA-232 carrying Klebsiella pneumoniae belonging to ST231 in India: multiple and varied mobile genetic elements [PDF]

BMC Microbiology, 2019
Background Recently, in India, there has been a shift from NDM to OXA48-like carbapenemases. OXA-181 and OXA-232 are the frequently produced variants of OXA48-like carbapenemases. OXA48-like carbapenemases are also known to be carried on transposons such
Chaitra Shankar, Purva Mathur, Manigandan Venkatesan, Agila Kumari Pragasam, Shalini Anandan, Surbhi Khurana, Balaji Veeraraghavan   +6 more
doaj   +2 more sources

Emergence of population heterogeneity in Klebsiella pneumoniae with a bla OXA-232-harboring plasmid: carbapenem resistance, virulence, and fitness [PDF]

Journal of Biomedical Science
Background This study aimed to investigate the population heterogeneity on carbapenem susceptibility in Klebsiella pneumoniae strains that acquired a bla OXA-232-bearing ColE-type plasmid. Methods A bla OXA-232-bearing plasmid was electroporated into two
Yun Young Cho, Sun Ju Kim, Kwan Soo Ko
doaj   +2 more sources

Genomics of Klebsiella pneumoniae ST16 producing NDM-1, CTX-M-15, and OXA-232 [PDF]

Clinical Microbiology and Infection, 2019
OBJECTIVES: Genomic characterization of the internationally spread sequence type (ST) 16 carbapenem-resistant Klebsiella pneumoniae. METHODS: The complete genomes of three carbapenem producing ST16 K.
Biscaro, V., Caltagirone, M., Carattoli, A., Espinal, P., Fernandes, M. R., MATTIONI MARCHETTI, VITTORIA, Migliavacca, R., Nucleo, E., Rigoli, R., Villa, L.   +9 more
core   +7 more sources