Results 41 to 50 of about 3,195 (172)

Draft Genome Sequence of a Multidrug-Resistant Sequence Type 231 Outbreak-Associated Clone of Klebsiella pneumoniae, KP41-2015, Producing OXA-232 Carbapenemase. [PDF]

Genome Announc, 2017
ABSTRACT Carbapenem-resistant Klebsiella pneumoniae infection is a rising public health threat due to limited therapeutic options. Here, we report the genome sequence of a multidrug-resistant K. pneumoniae sequence type 231 (ST231) strain associated with an outbreak of infections in
Abdul Momin MHF, Liakopoulos A, Wareham DW.   +2 more
europepmc   +6 more sources

Draft Genome Sequences of Four NDM-1-Producing Klebsiella pneumoniae Strains from a Health Care Facility in Northern California. [PDF]

, 2015
We report the draft genome sequences of Klebsiella pneumoniae strains from four patients at a northern California health care facility. All strains contained the New Delhi metallo-β-lactamase (NDM1) carbapenemase with extended antibiotic resistance ...
Chaturvedi, Vishnu, Chorny, Ilya, Greninger, Alexander L, Knowles, Susan, Ng, Valerie L   +4 more
core   +1 more source

OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014 [PDF]

, 2017
Objectives: OXA-48-like carbapenemases have spread worldwide since 2001. We analysed patient and microbiological data for UK isolates with these enzymes as confirmed by the national reference laboratory from November 2007 - December 2014.
Doumith, Michel, Findlay, Jacqueline, Hill, Robert, Hopkins, Katie L, Livermore, David M., Loy, Richard, Meunier, Danièle, Mustafa, Nazim, Pike, Rachel, Woodford, Neil   +9 more
core   +1 more source

Molecular and Phenotypic Characterization of a Multidrug-Resistant Escherichia coli Coproducing OXA-232 and MCR - 1.1 in Argentina

Microbial Drug Resistance, 2022
The spread of c arbapenem-resistant Enterobacterales has raised concern in clinical settings due to the limited therapeutic options available. OXA-48–like enzymes are still sporadic in South America.
García, Javier F., Nastro, Marcela, Dabos, Laura, Campos, Josefina, Traglia, German, Ocampo, Cecilia Vera, Famiglietti, Ángela, Rodriguez, Carlos, Vay, Carlos   +8 more
openaire   +3 more sources

Complete Genome Sequence of Klebsiella pneumoniae subsp. pneumoniae KP617, Coproducing OXA-232 and NDM-1 Carbapenemases, Isolated in South Korea. [PDF]

Genome Announc, 2016
ABSTRACT The prevalence of Klebsiella pneumoniae coproducing carbapenemase metallo-β-lactamase 1 (NDM-1) and OXA-48 has been increasing globally since 2013. The complete genome of KP617 was sequenced and assembled into a circular chromosome and two plasmids.
Kwon T, Yang JW, Lee S, Yun MR, Yoo WG, Kim HS, Cha JO, Kim DW.   +7 more
europepmc   +4 more sources

Validation of Hexaplex Recombinase Polymerase Amplification Assay for the Detection of Carbapenemase Genes in Klebsiella pneumoniae Isolates From Pediatric Inpatients. [PDF]

J Clin Lab Anal
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Mutitanon S, Chaichanawongsaroj N.
europepmc   +2 more sources

Rapid Genomic Characterization and Global Surveillance of Klebsiella Using Pathogenwatch [PDF]

, 2021
Background: Klebsiella species, including the notable pathogen K. pneumoniae, are increasingly associated with antimicrobial resistance (AMR). Genome-based surveillance can inform interventions aimed at controlling AMR.
Aanensen, David M, Abrudan, Monica, Abudahab, Khalil, Afolayan, Ayorinde O, Ajiboye, Jolaade J, Arevalo, Alejandra, Argimón, Silvia, Brisse, Sylvain, Carlos, Celia, David, Sophia, Donado-Godoy, Pilar, Ewomazino odih, Erkison, Fabian bernal, Johan, Feil, Edward J, Fernanda valencia, Maria, Gayeta, June M, Goater, Richard, Govindan, Vandana, Harste, Harry, Herrera, Elmer M, Holt, Kathryn, Kekre, Mihir, Lagrada, Marietta L, Macaranas, Polle Krystle V, Masim, Melissa Ana L, Molloy, Ali, Muddyman, Dawn, Nagaraj, Geetha, Oaikhena, Anderson O, Okeke, Iruka N, Olorosa, Agnettah M, Osma castro, Erik C D, Prabhu, Akshata, Ravikumar, K L, Ravishankar, K N, Rose, Steffimole, Shamanna, Varun, Shincy, M R, Sravani, D, Stelling, John, Taylor, Ben, Underwood, Anthony, Wheeler, Nicole E, Yeats, Corin A   +43 more
core   +1 more source

OXA β-lactamases [PDF]

, 2014
The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Brink AJ, Espinal P, Goncalves D, Lyon JA, Potron A, Summers DK   +5 more
core   +2 more sources

Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing. [PDF]

Antimicrob Agents Chemother, 2014
ABSTRACT The whole-genome sequence of a carbapenem-resistant Klebsiella pneumoniae strain, PittNDM01, which coproduces NDM-1 and OXA-232 carbapenemases, was determined in this study. The use of single-molecule, real-time (SMRT) sequencing provided a closed genome in a single sequencing run.
Doi Y, Hazen TH, Boitano M, Tsai YC, Clark TA, Korlach J, Rasko DA.   +6 more
europepmc   +4 more sources

Characterisation of OXA-244, a chromosomally-encoded OXA-48-like β-lactamase from Escherichia coli [PDF]

, 2016
International audienceABSTRACT Shewanella spp. constitute a reservoir of antibiotic resistance determinants. In a bile sample, we identified three extended-spectrum-β-lactamase (ESBL)-producing bacteria ( Escherichia coli , Klebsiella pneumoniae , and ...
Dortet, Laurent, Nordmann, Patrice, Poirel, Laurent, Potron, Anaïs   +3 more
core   +3 more sources