Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France [PDF]
We characterized 53 OXA-48-producing Klebsiella pneumoniae (OXA-48-Kp) isolated between 2011 and 2013 in 21 French hospitals. All the isolates were genotyped using MLST and PFGE and the population structure of the species was determined by a nucleotide-based analysis of the entire K. pneumoniae MLST database.
Liapis, E. +14 more
openaire +6 more sources
OXA-48-like carbapenemases producing Enterobacteriaceae in different niches [PDF]
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are widely distributed among Enterobacteriaceae, with significant geographical differences.
Mairi, Assia +4 more
openaire +4 more sources
Emergence of OXA-48-Producing Klebsiella pneumoniae in Taiwan [PDF]
The isolation of OXA-48-producing Enterobacteriaceae has increased dramatically in Mediterranean countries in the past 10 years, and has recently emerged in Asia. Between January 2012 and May 2014, a total of 760 carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) isolates were collected during a Taiwan national surveillance.
Ling Ma +7 more
openaire +5 more sources
OXA-48-like carbapenemases in Proteus mirabilis – novel genetic environments and a challenge for detection [PDF]
OXA-48-like enzymes represent the most frequently detected carbapenemases in Enterobacterales in Western Europe, North Africa and the Middle East. In contrast to other species, the presence of OXA-48-like in Proteus mirabilis leads to an unusually ...
Janko Sattler +11 more
doaj +2 more sources
Emergence of OXA-48 Carbapenemase in Taiwan
[[abstract]]Purpose: OXA-48 producing Enterbacteriaceae are increased dramatically in Mediterranean countries in the past ten years. It has been found in Asia recently. Here, we report the emergence of OXA-48 during a nationwide survey in Taiwan. Methods:
Ma, Ling +8 more
openaire +2 more sources
Spread of the blaOXA-48/IncL Plasmid within and between Dogs in City Parks, France
The blaOXA-48/IncL plasmid is increasingly reported in dogs, even in the absence of carbapenem use in animals. In this study, we witnessed the spread of this plasmid within and between dogs sharing the same relaxing area.
Marisa Haenni +4 more
doaj +1 more source
Treatment of Infections by OXA-48-Producing Enterobacteriaceae [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) contribute significantly to the global public health threat of antimicrobial resistance. OXA-48 and its variants are unique carbapenemases with low-level hydrolytic activity toward carbapenems but no intrinsic activity against expanded-spectrum cephalosporins.
Adam Stewart +3 more
openaire +5 more sources
Multiscale simulations identify origins of differential carbapenem hydrolysis by the OXA-48 β-lactamase [PDF]
OXA-48 β-lactamases are frequently encountered in bacterial infections caused by carbapenem-resistant Gram-negative bacteria. Due to the importance of carbapenems in treatment of healthcare-associated infections, and the increasingly wide dissemination ...
Marc, van der Kamp +4 more
core +2 more sources
Molecular analysis of OXA-48-producing Escherichia coli in Switzerland from 2019 to 2020. [PDF]
OXA-48-type ß-lactamases are the most prevalent carbapenemase-type in Enterobacterales in Switzerland, predominantly found in Escherichia coli and Klebsiella pneumoniae.
Poirel, L. +7 more
core +2 more sources
OXA-48-like carbapenemases: the phantom menace [PDF]
OXA-48-type carbapenem-hydrolysing class D β-lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been identified, with OXA-48 being the most widespread. They differ by a few amino acid substitutions or deletions (one to five amino acids).
Laurent, Poirel +2 more
openaire +2 more sources

