Results 21 to 30 of about 24,184 (203)
OXA-48-like carbapenemases: the phantom menace [PDF]
Journal of Antimicrobial Chemotherapy, 2012 OXA-48-type carbapenem-hydrolysing class D β-lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been identified, with OXA-48 being the most widespread. They differ by a few amino acid substitutions or deletions (one to five amino acids).
Laurent, Poirel +2 more
openaire +2 more sources
Evaluation of a New Phenotypic OXA-48 Disk Test for Differentiation of OXA-48 Carbapenemase-Producing Enterobacteriaceae Clinical Isolates [PDF]
Journal of Clinical Microbiology, 2015 ABSTRACT The current phenotypic methods for detecting carbapenemase-producing Enterobacteriaceae (CPE) allow differentiation between class A and B carbapenemases, but they cannot confirm in a single test class D OXA-48 carbapenemase producers.
Tsakris, A. +5 more
openaire +3 more sources
Characterization of OXA-48-producing Klebsiella oxytoca isolates from a hospital outbreak in Tunisia
Journal of Global Antimicrobial Resistance, 2021 Objective: There is very limited information about OXA-48-producing Klebsiella oxytoca. The aim of this study was to describe the phenotypic and molecular characterization of OXA-48-producing K.
Julia Guzmán-Puche +7 more
doaj +1 more source
Epidemic spread of OXA-48 beta-lactamase in Croatia [PDF]
Journal of Medical Microbiology, 2018 A dramatic increase in OXA-48 β-lactamase was observed recently not only in large hospital centres, but also in smaller suburban hospital centres in geographic areas bordering Croatia. The aim of the study was to analyse the epidemiology, the mechanisms of antibiotic resistance and the routes of spread of OXA-48 carbapenemase in Croatia.Carbapenemase ...
Bedenić, Branka +20 more
openaire +5 more sources
Journal of Global Infectious Diseases, 2016 Carbapenemase producing Gram-negative pathogen is of great concern for physician. The challenging aspects are treatment option and infection control.
Yamuna Devi Bakthavatchalam +2 more
doaj +1 more source
One-Step Differential Detection of OXA-48-Like Variants Using High-Resolution Melting (HRM) Analysis
Antibiotics, 2020 OXA-48-like carbapenemase gene remains a hidden threat, as different OXA-48 variants have varying presentations of susceptibility to antibiotics that might affect the treatment decisions.
Min Yi Lau +6 more
doaj +1 more source
Spread of OXA-48-Encoding Plasmid in Turkey and Beyond [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT Eighteen carbapenem-resistant, OXA-48-positive enterobacterial isolates recovered from Turkey, Lebanon, Egypt, France, and Belgium were analyzed. In most isolates, similar 70-kb plasmids carrying the carbapenemase gene bla OXA-48 were identified.
Carrer, Amelie +8 more
openaire +4 more sources
Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors
Frontiers in Pharmacology, 2022 Carbapenem resistance in Enterobacteriaceae caused by OXA-48 β-lactamase is a growing global health threat and has rapidly spread in many regions of the world. Developing inhibitors is a promising way to overcome antibiotic resistance. However, there are
Yuejuan Zhang +14 more
doaj +1 more source
Concurrent interspecies and clonal dissemination of OXA-48 carbapenemase [PDF]
Clinical Microbiology and Infection, 2015 Several isolates of four different carbapenemase-producing Enterobacteriaceae species were recovered from a patient hospitalized for 4 months in a teaching hospital in Madrid. These species comprised seven Klebsiella pneumoniae belonging to ST15, four Escherichia coli belonging to ST2531, two Serratia marcescens and one Citrobacter freundii.
Arana, D.M. +7 more
openaire +2 more sources
Infection and Drug Resistance, 2022 Yicheng Wen,1,* Xiaofang Xie,1,* Ping Xu,2,* Chengcheng Yang,1 Zhichen Zhu,1 Jie Zhu,1 Jingnan Lv,1 Haifang Zhang,1 Liang Chen,3,4 Hong Du1 1Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou ...
Wen Y +9 more
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