Results 21 to 30 of about 1,076,076 (217)

OXA-48-like carbapenemases producing Enterobacteriaceae in different niches [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2017
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are widely distributed among Enterobacteriaceae, with significant geographical differences.
Assia, Mairi, Alix, Pantel, Albert, Sotto, Jean-Philippe, Lavigne, Aziz, Touati   +4 more
openaire   +3 more sources

Evaluation of OXA-48 K-Se T: an immunochromatographic assay for rapid detection of OXA-48–producing Enterobacteriaceae

Diagnostic Microbiology and Infectious Disease, 2016
The OXA-48 K-Se T, a new immunochromatographic assay for rapid detection of OXA-48-producing Enterobacteriaceae, has been evaluated in a Spanish Hospital during a 3-month period. A collection of 100 Enterobacteriaceae including 79 isolates producing OXA-48 has been tested. Sensitivity and specificity of 100% were obtained.
Javier, Fernández, Ana, Fleites, María Rosario, Rodcio, Fernando, Vazquez   +3 more
openaire   +3 more sources

NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman

Clinical Microbiology and Infection, 2012
Twenty-two carbapenem-resistant enterobacterial isolates were recovered from patients hospitalized between October 2010 and March 2011 at the Royal Hospital of Muscat, Sultanate of Oman.
Laurent Dortet, Laurent Poirel, Patrice Nordmann   +2 more
exaly   +2 more sources

Early detection of OXA-48 producing Klebsiella pneumoniae with the use of rapid antibiotic susceptibility testing. [PDF]

Eur J Clin Microbiol Infect Dis
Rapid antimicrobial susceptibility testing of positive blood cultures can enhance antimicrobial stewardship and patient outcomes. We present a case where OXA-48-producing Klebsiella pneumoniae with low-level carbapenem resistance was suspected 6 h after ...
De Muynck E, Vandendriessche S, Messiaen AS, Decommer K, Huis In 't Veld D, De Waele JJ, Boelens J.   +6 more
europepmc   +2 more sources

Emergence of OXA-48-like Carbapenemase-Producing Escherichia coli in Baranya County, Hungary. [PDF]

Antibiotics (Basel)
Background: Carbapenem-resistant Escherichia coli (CREC) producing OXA-48-like carbapenemase was first detected in Hungary in 2022. The aim of the present study was to characterize such strains isolated in 2022–2025 in Baranya County, Hungary.
Mohamed FA, Al-Bulushi M, Melegh S, Timmer B, Meszéna R, Freytag C, Laczkó L, Miló L, Urbán P, Bőkényné-Tóth R, Gyenesei A, Kardos G, Nyul A, Urbán E, Pál T, Sonnevend Á.   +15 more
europepmc   +2 more sources

Spread of the blaOXA-48/IncL Plasmid within and between Dogs in City Parks, France

Microbiology Spectrum, 2022
The blaOXA-48/IncL plasmid is increasingly reported in dogs, even in the absence of carbapenem use in animals. In this study, we witnessed the spread of this plasmid within and between dogs sharing the same relaxing area.
Marisa Haenni, Véronique Métayer, Agnese Lupo, Antoine Drapeau, Jean-Yves Madec   +4 more
doaj   +1 more source

Treatment of Infections by OXA-48-Producing Enterobacteriaceae [PDF]

Antimicrobial Agents and Chemotherapy, 2018
Carbapenemase-producing Enterobacteriaceae (CPE) contribute significantly to the global public health threat of antimicrobial resistance. OXA-48 and its variants are unique carbapenemases with low-level hydrolytic activity toward carbapenems but no intrinsic activity against expanded-spectrum cephalosporins.
Adam Stewart, Patrick Harris, Andrew Henderson, David Paterson   +3 more
openaire   +5 more sources

Molecular analysis of OXA-48-producing Escherichia coli in Switzerland from 2019 to 2020. [PDF]

, 2022
OXA-48-type ß-lactamases are the most prevalent carbapenemase-type in Enterobacterales in Switzerland, predominantly found in Escherichia coli and Klebsiella pneumoniae.
Poirel, L., Nordmann, P., Perreten, V., Findlay, Jacqueline, Findlay, J., Perreten, Vincent, Nordmann, Patrice, Poirel, Laurent   +7 more
core   +1 more source

Electrostatic interactions define nacubactam potency against OXA-48-like β-lactamases

Carbapenemases, β-lactamases hydrolysing carbapenem antibiotics, severely challenge treatment of multi-drug resistant bacterial infections. OXA-48 is among the most widely disseminated carbapenemases in Enterobacterales, consequently new treatment ...
Hoff JF, Goudar KE, Beer M, Hinchliffe P, Shaw JM, Tooke CL, Takebayashi Y, Mulholland AJ, Schofield CJ, Spencer J.   +9 more
europepmc   +2 more sources

OXA-48-like carbapenemases: the phantom menace [PDF]

Journal of Antimicrobial Chemotherapy, 2012
OXA-48-type carbapenem-hydrolysing class D β-lactamases are increasingly reported in enterobacterial species. To date, six OXA-48-like variants have been identified, with OXA-48 being the most widespread. They differ by a few amino acid substitutions or deletions (one to five amino acids).
Laurent, Poirel, Anaïs, Potron, Patrice, Nordmann   +2 more
openaire   +2 more sources