Results 11 to 20 of about 27,017 (217)

NDM-1 encoded by a pNDM-BJ01-like plasmid p3SP-NDM in clinical Enterobacter aerogenes [PDF]

open access: yesFrontiers in Microbiology, 2015
A carbapenem-nonsusceptible Enterobacter aerogenes strain named 3-SP was isolated from a human case of pneumonia in a Chinese teaching hospital. NDM-1 carbapenemase is produced by a pNDM-BJ01-like conjugative plasmid designated p3SP-NDM to account for carbapenem resistance of 3-SP. p3SP-NDM was fully sequenced and compared with all publically available
Changting Liu   +2 more
exaly   +5 more sources

First identification of novel NDM carbapenemase, NDM-7, in Escherichia coli in France. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The NDM-1 carbapenemase has been identified in 2008 in Enterobacteriaceae. Since then, several reports have emphasized its rapid dissemination throughout the world.
Gaelle Cuzon   +2 more
doaj   +5 more sources

Genomic characterization of an NDM-9-producing Acinetobacter baumannii clinical isolate and role of Glu152Lys substitution in the enhanced cefiderocol hydrolysis of NDM-9 [PDF]

open access: yesFrontiers in Microbiology, 2023
Here, we characterized the first French NDM-9-producing Acinetobacter baumannii isolate. A. baumannii 13A297, which belonged to the STPas25 (international clone IC7), was highly resistant to β-lactams including cefiderocol (MIC >32 mg/L). Whole genome
Patrick Plesiat   +2 more
exaly   +5 more sources

Molecular and computational approaches to understand resistance of New Delhi metallo β-lactamase variants (NDM-1, NDM-4, NDM-5, NDM-6, NDM-7)-producing strains against carbapenems

open access: yesJournal of Biomolecular Structure and Dynamics, 2018
The discovery of NDM-1 and its variants has caused the emergence of antibiotic resistance in the community and hospital setting, causing major concern for health care across the globe. New Delhi Metallo-β-lactamase is known to hydrolyse almost all β-lactam antibiotics.
Abid Ali   +4 more
openaire   +3 more sources

How To Detect NDM-1 Producers [PDF]

open access: yesJournal of Clinical Microbiology, 2011
ABSTRACT Enterobacterial isolates expressing the carbapenemase NDM-1 are emerging worldwide. Twenty-seven NDM-1-positive isolates of worldwide origin were included in this study to identify these strains as not only pathogens but also colonizers of normal flora for infection control screening.
Nordmann, P.   +4 more
openaire   +4 more sources

Metallo-Beta-Lactamases: NDM

open access: yesJournal of Education, Health and Sport, 2019
New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli. It determines these bacteria resistance to the majority of known antibiotics.
Kamil Leis   +13 more
doaj   +8 more sources

PHT427 as an effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor restored the susceptibility of meropenem against Enterobacteriaceae producing NDM-1 [PDF]

open access: yesFrontiers in Microbiology, 2023
IntroductionWith the increasingly serious problem of bacterial drug resistance caused by NDM-1, it is an important strategy to find effective inhibitors to assist β-lactam antibiotic treatment against NDM-1 resistant bacteria.
Xiaohui Li   +11 more
doaj   +2 more sources

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

open access: yesScientific Reports, 2021
Inhibition of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome has recently emerged as a promising therapeutic target for several inflammatory diseases.
Sohaib Nizami   +9 more
doaj   +1 more source

Antibiotic-resistance genes in E. coli strains in GCC countries: A meta-analysis

open access: yesSaudi Journal of Medicine and Medical Sciences, 2022
Background: Antimicrobial resistance (AMR) in Escherichia coli is an alarming issue worldwide, including in the Gulf Cooperation Council (GCC) countries, yet the prevailing gene patterns have not recently been reviewed.
Khalid Mubarak Bindayna   +3 more
doaj   +1 more source

Genotypic Distribution and Antimicrobial Susceptibilities of Carbapenemase-Producing Enterobacteriaceae Isolated in Tertiary Care Hospital in South India

open access: yesJournal of Pure and Applied Microbiology, 2022
Antimicrobial resistance has emerged as a major danger to contemporary medicine around the world. Carbapenems are the highest class of B-lactam drugs which are considered as the most effective and safest antibiotics available.
S. Abhishek   +3 more
doaj   +1 more source

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