Emergence of KPC new variants (KPC-16 and KPC-17) and ongoing outbreak in southern Taiwan [PDF]
Clinical Microbiology and Infection, 2015 We first describe two novel variants of blaKPC, blaKPC-16 and blaKPC-17, which were identified in three Klebsiella pneumoniae isolates from a patient in Taiwan. KPC-16 and KPC-17 differed from KPC-2 by two (P202S and F207L) and a single (F207L) amino acid substitutions, respectively. All three isolates with identical pulsotype belonged to sequence type
M-C Chang, Y-C Chuang, Y -C Chuang
exaly +3 more sources
Management of KPC-producing Klebsiella pneumoniae infections [PDF]
Clinical Microbiology and Infection, 2018 Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has become one of the most important contemporary pathogens, especially in endemic areas.To provide practical suggestion for physicians dealing with the management of KPC-KP infections in critically ill patients, based on expert opinions.PubMed search for relevant publications ...
Francesco Giuseppe De Rosa +2 more
exaly +8 more sources
Phenotypic and enzymatic comparative analysis of the KPC variants, KPC-2 and its recently discovered variant KPC-15. [PDF]
PLoS ONE, 2014 Sixteen different variants (KPC-2 to KPC-17) in the KPC family have been reported, and most current studies are focusing on KPC-2 and KPC-3. The KPC-15 variant, which isolated from Klebsiella pneumoniae in a Chinese hospital, was a recently discovered ...
Dongguo Wang +4 more
doaj +4 more sources
How to manage KPC infections [PDF]
Therapeutic Advances in Infectious Disease, 2020 Carbapenemase-producing Enterobacteriaceae represent an increasing global threat worldwide and Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has become one of the most important contemporary pathogens, especially in endemic areas. Risk stratification and rapid diagnostics laboratory workflows are of paramount importance and
Matteo Bassetti, Maddalena Peghin
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Comparative Study of Graft Placement Between Medial and Lateral to Malleus in Tympanoplasty
Bengal Journal of Otolaryngology and Head Neck Surgery, 2023 Introduction Tympanoplasty is a surgical method, to eradicate middle ear infection and improve its function. In tympanoplasty graft can be by overlay or underlay technique.
Somnath Ray +4 more
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Comparison between Cold Steel Method and Bipolar Diathermy Method of Tonsillectomy
Bengal Journal of Otolaryngology and Head Neck Surgery, 2023 Introduction It is generally accepted that the ideal method of tonsillectomy should have less operative time, blood loss, post-operative haemorrhage and morbidity.1 Objective: To compare post-operative pain, intra-operative blood loss and duration ...
Mohammad Naksh Kamar +4 more
doaj +1 more source
Phenotypic and Enzymatic Comparative Analysis of the Novel KPC Variant KPC-5 and Its Evolutionary Variants, KPC-2 and KPC-4 [PDF]
Antimicrobial Agents and Chemotherapy, 2009 ABSTRACT A novel Klebsiella pneumoniae carbapenemase (KPC) variant, designated bla KPC-5 , was discovered in a carbapenem-resistant Pseudomonas aeruginosa clinical isolate from Puerto Rico.
Daniel J, Wolter +5 more
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Clinical Diabetology, 2022 BACKGROUND: The obesity pandemic is triggering the tsunami of type 2 diabetes mellitus (T2DM) worldwide. Sodium-glucose transport protein 2 inhibitors (SGLT2i) have demonstrated weight loss in clinical trials.
Rishad Ahmed +3 more
doaj +1 more source
Act Fast as Time Is Less: High Faecal Carriage of Carbapenem-Resistant Enterobacteriaceae in Critical Care Patients [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) are drug-resistant Gram-negative bacteria that are present in the community as well as in hospitals.
Sanjith Saseedharan +3 more
doaj +1 more source
The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones ofKlebsiella pneumoniaeST11/KPC-2, ST101/KPC-2 and ST512/KPC-3 [PDF]
Journal of Antimicrobial Chemotherapy, 2016 We analysed the microbiological traits and population structure of KPC-producing Enterobacteriaceae isolates collected in Spain between 2012 and 2014. We also performed a comparative WGS analysis of the three major KPC-producing Klebsiella pneumoniae clones detected.Carbapenemase and ESBL genes were sequenced. The Institut Pasteur MLST scheme was used.
Jesús, Oteo +10 more
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