Phenotypic and Enzymatic Comparative Analysis of the Novel KPC Variant KPC-5 and Its Evolutionary Variants, KPC-2 and KPC-4 [PDF]
ABSTRACT A novel Klebsiella pneumoniae carbapenemase (KPC) variant, designated bla KPC-5 , was discovered in a carbapenem-resistant Pseudomonas aeruginosa clinical isolate from Puerto Rico.
Daniel J, Wolter +5 more
openaire +2 more sources
The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones ofKlebsiella pneumoniaeST11/KPC-2, ST101/KPC-2 and ST512/KPC-3 [PDF]
We analysed the microbiological traits and population structure of KPC-producing Enterobacteriaceae isolates collected in Spain between 2012 and 2014. We also performed a comparative WGS analysis of the three major KPC-producing Klebsiella pneumoniae clones detected.Carbapenemase and ESBL genes were sequenced. The Institut Pasteur MLST scheme was used.
Jesús, Oteo +10 more
openaire +2 more sources
Evaluation of the Ability to Form Biofilms in KPC-Producing and ESBL-Producing Klebsiella pneumoniae Isolated from Clinical Samples [PDF]
The appearance of Klebsiella pneumoniae strains producing extended-spectrum β-lactamase (ESBL), and carbapenemase (KPC) has turned into a significant public health issue. ESBL- and KPC-producing K.
Sónia Ramos +17 more
core +1 more source
Reduced mortality from KPC-K.pneumoniae bloodstream infection in high-risk patients with hematological malignancies colonized by KPC-K.pneumoniae [PDF]
Background: KPC-K.pneumoniae bloodstream infection (KPC-KpBSI) mortality rate in patients with hematological malignancies is reported about 60%. The initial treatment active against KPC-K.pneumoniae is crucial for survival and KPC-K.pneumoniae rectal ...
Santilli S. +12 more
core +1 more source
First report of KPC-type carbapenemase in Pseudomonas aeruginosa at a peruvian hospital
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Gina Salvador-Luján +4 more
doaj +1 more source
THE MASS PROFILE OF THE GALAXY TO 80 kpc [PDF]
matches version accepted to ApJ ...
Gnedin, Oleg Y. +3 more
openaire +2 more sources
Background: The prevalence of carbapenemase-producing Enterobacteriaceae (CPE), especially the KPC-2-producing Klebisella pneumoniae, is rapidly increasing and becoming a menace to global public health.
Jun Sung Hong +6 more
doaj +1 more source
The Changing Epidemiology of Carbapenemase-Producing Enterobacterales
Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein +7 more
doaj +1 more source
KPC-derived organoid tumor histopathology features.
KPC-derived organoid tumor stained for hyaluronic acid (A), pimonidazole (B), collagen (green) and Meca32 (red) (C). Co-staining of pimonidazole (green) and Meca-32 (red) (D) showing vessels present in both oxic and hypoxic tissue. Black scale bar = 5 mm.
John L. Humm (8720559) +6 more
core +1 more source
This study reports on the characterization of a Klebsiella pneumoniae clinical isolate showing high-level resistance to ceftazidime-avibactam associated with the production of KPC-53, a KPC-3 variant exhibiting a Leu167Glu168 duplication in the Ω-loop and a loss of carbapenemase activity.
Di Pilato V. +7 more
openaire +3 more sources

