Results 41 to 50 of about 24,572 (190)

Preductal postductal oxygen saturation gradient in preterm infants immediately after birth: Effect of gestational age on achievement of target saturation

Asian Journal of Medical Sciences, 2023
Background: The delivery room oxygen saturation (SpO2) monitoring in neonates is based on studies in term infants. Study of preductal-postductal SpO2 gradient in healthy preterms immediately after birth will help in follow-up of an abnormal gradient ...
Shaon Mitra , Arnab Mondal
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Muscle Tear and Subsequent Muscle Infarction in a Patient With Uncontrolled Type 2 Diabetes Mellitus

Annals of Internal Medicine: Clinical Cases
Diabetes mellitus is associated with multiple microvascular and macrovascular complications. Musculoskeletal complications, such as diabetic muscle infarction, diabetic tendinopathy, Dupuytren contracture, cheiroarthropathy, and adhesive capsulitis ...
Dipra Dattasarma, Nirmalya Roy, Mainak Mandal, Sayantani Ghosh, Akriti Singh, Abhishek Praharaj, Soumyadeep Maity, Abhishek Chanda   +7 more
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Rapid Screening for Carbapenem Resistant Organisms: Current Results and Future Approaches [PDF]

Journal of Clinical and Diagnostic Research, 2015
Carbapenem producing Enterobacteriaceae (CPE) is a major public health threat. A total of 120 carbapenem resistant E.coli (n=32) and K.pneumoniae (n=88) from blood stream infections were screened for the presence of carbapenem resistant genes KPC, NDM ...
Shalini Anandan, Sunganya Damodaran, Radha Gopi, Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan   +4 more
doaj   +1 more source

Efficacy and safety of insulin degludec in renal transplant recipients with pre-existing diabetes

Endocrine and Metabolic Science, 2021
Introduction: Glycemic control is important in renal transplant receptions with diabetes. In the early post-transplant period, recovering renal function and concomitant steroids and immunosuppressants increase the risk of dysglycemia which adversely ...
Debmalya Sanyal, Soumyabrata Roy Chaudhuri, Anirban Majumder   +2 more
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WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

Advanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki, Aori Minami, Misako Hirota, Mirei Hirano, Ryota Sato, Atsuki Honma, Hideto Ueki, Toshiro Shirakawa   +7 more
wiley   +1 more source

The central kpc of edge-on AGN [PDF]

Proceedings of Nuclei of Seyfert galaxies and QSOs - Central engine & conditions of star formation — PoS(Seyfert 2012), 2013
The NIR is less influenced by dust extinction than optical light. This enables us to look to an extent through dusty regions. In addition, it is sensitive to the mass-dominating stellar population. The combination of NIR imaging and spectroscopy of the VLT integral field spectrograph SINFONI gives us the opportunity to analyze several emission and ...
Smajić, Semir, Fischer, Sebastian, Zuther, Jenz, Valencia-S., Monica, Eckart, Andreas   +4 more
openaire   +2 more sources

In vitro Combined Inhibitory Activities of β-Lactam Antibiotics and Clavulanic Acid Against blaKPC-2-Positive Klebsiella pneumoniae

Infection and Drug Resistance, 2021
Mingjia Peng,1,2 Renru Han,1,2 Yan Guo,1,2 Yonggui Zheng,1,2 Feifei Yang,1,2 Xiaogang Xu,1,2 Fupin Hu1,2 1Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Key Laboratory of Clinical Pharmacology ...
Peng M, Han R, Guo Y, Zheng Y, Yang F, Xu X, Hu F   +6 more
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Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo, Rong Hu, Yuhang Hu, Ping Hu, Shengbo Han, Guozheng Lv, Zhu Zeng, Yong Zhao, Yang Li, Yan Huang, Yingsong Zhao, Hongda Wang, Guangyu Zhao, Eryang Zhao, Gang Zhao   +14 more
wiley   +1 more source

Antigen Spreading via Localized Administration Enhances Adoptive TCR‐T Cell Therapy in Pancreatic Cancer

Advanced Science, EarlyView.
Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang, Qin Wang, Zhuo Yao, Qing Wang, Yongtao Ji, Minqi Yang, Meng Wang, Shiyi Shao, Xinyu Zhao, Fu Zhang, Tingbo Liang, Qida Hu   +11 more
wiley   +1 more source

Phenotypic and Genetic Analysis of KPC-49, a KPC-2 Variant Conferring Resistance to Ceftazidime–Avibactam and Maintaining Resistance to Imipenem and Meropenem

Infection and Drug Resistance, 2023
Meng Yu, Qingzheng Wei, Weiqing Song, Jiangshui Yuan Clinical Laboratory, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, Shandong, People’s Republic of ChinaCorrespondence: Jiangshui Yuan; Weiqing Song, Clinical ...
Yu M, Wei Q, Song W, Yuan J
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