The Simplified Carbapenem Inactivation Method (sCIM) for Simple and Accurate Detection of Carbapenemase-Producing Gram-Negative Bacilli [PDF]
Frontiers in Microbiology, 2018 This study reports the simplified carbapenem inactivation method (sCIM) to detect carbapenemase-producing gram-negative bacilli in a simple and accurate manner.
Xiaopeng Jing +15 more
doaj +9 more sources
The optimized carbapenem inactivation method for objective and accurate detection of carbapenemase-producing Acinetobacter baumannii [PDF]
Frontiers in Microbiology, 2023 The modified carbapenem inactivation method (mCIM) recommended by the Clinical and Laboratory Standards Institute is not applicable for detecting carbapenemases in Acinetobacter baumannii. Four currently reported phenotypic detection methods, namely, the
Sirui Zhang +13 more
doaj +6 more sources
A Variant Carbapenem Inactivation Method (CIM) for Acinetobacter baumannii Group with Shortened Time-to-Result: rCIM-A. [PDF]
Pathogens, 2022 Carbapenem-resistant Acinetobacter baumannii group organisms (CRAB) are challenging because the choice between targeted, new antibiotic drug options and hygiene measures should be guided by a timely identification of resistance mechanisms. In CRAB, acquired class-D carbapenemases (CHDLs) are active against meropenem and imipenem. If PCR methods are not
Mitteregger D +5 more
europepmc +7 more sources
A Four-Hour Carbapenem Inactivation Method (CIMB.S) Using Bacillus stearothermophilus as Indicator Strain [PDF]
Frontiers in Medicine, 2020 Objectives: There is an urgent need for accurate and fast diagnostic tests to identify carbapenemase-producing bacteria. Here we used Bacillus stearothermophilus as an indicator strain in the format of the carbapenem inactivation method (CIM) procedure ...
Ze-Hua Cui +26 more
doaj +5 more sources
Journal of Pure and Applied Microbiology, 2022 There is an alarming rise in carbapenem-resistant Enterobacteriaceae (CRE) causing nosocomial infections such as ventilator-associated respiratory infections (VARIs).
Nupur Koul +2 more
doaj +2 more sources
Modified Carbapenem Inactivation Method and Ethylenediaminetetraacetic Acid (EDTA)-Carbapenem Inactivation Method for Detection of Carbapenemase-Producing Enterobacterales and Pseudomonas aeruginosa. [PDF]
CureusThe rising incidence of carbapenem resistance in Enterobacterales and Pseudomonas aeruginosa is a concern. Since carbapenemase production is the primary resistance mechanism, detecting and identifying the genes responsible for it is crucial to effectively monitor its spread.This study aims to detect positivity for the modified carbapenem inactivation ...
Verma G +7 more
europepmc +3 more sources
Evaluation of carbapenem inactivation method-based phenotypic assays for the detection of GES-type carbapenemases in Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii [PDF]
Journal of Clinical MicrobiologyDetection of GES-type carbapenemases remains challenging because of their low prevalence and frequently weak hydrolytic activity against carbapenems.
Samuel García-García +19 more
doaj +2 more sources
Application of Modified Carbapenem Inactivation Method and Its Derivative Tests for the Detection of Carbapenemase-Producing Aeromonas. [PDF]
Infect Drug Resist, 2021 Infection and transmission of carbapenem-resistant Aeromonas is a serious threat to public health. Rapid and accurate detection carbapenem-resistant of these organisms is essential for reasonable treatment and infection control. This study aimed to find a simple and effective method to detect carbapenem-resistant phenotype in Aeromonas.A total of 131 ...
Wang Y, Liu H, Zhang L, Sun B.
europepmc +6 more sources
Evaluation of Modified Rapid Carbapenem Inactivation Method (mrCIM) Combined with Rapid EDTA-Modified Carbapenem Inactivation Method (reCIM) to Detect Carbapenemase and Distinguish Metallo-Carbapenemase in Enterobacteriaceae Within Four Hours. [PDF]
Infect Drug Resist, 2020 To develop a rapid EDTA-modified carbapenem inactivation method (reCIM) combined with modified rapid carbapenem inactivation method (mrCIM) to detect carbapenemase and distinguish metallo-β-lactamases from carbapenemases in Enterobacteriaceae in 4 hrs.The sensitivities and specificities of mrCIM and reCIM were retrospectively evaluated in 247 ...
Wei Q +5 more
europepmc +5 more sources
Rapid Detection and Characterization of Carbapenemases in Enterobacterales with a New Modified Carbapenem Inactivation Method, mCIMplus. [PDF]
J Clin Microbiol, 2020 The worldwide emergence and spread of antimicrobial resistance in Gram-negative bacteria are severely limiting therapeutic options and thus constitute a major public health threat. The timely accurate detection of carbapenemase producers and the determination of carbapenemase class according to the Ambler classification can guide antimicrobial therapy ...
Petit M +7 more
europepmc +4 more sources