Results 21 to 30 of about 11,730,789 (176)

Adjustment of Modified Carbapenem Inactivation Method Conditions for Rapid Detection of Carbapenemase-Producing Acinetobacter baumannii. [PDF]

Ann Lab Med, 2020
The existing modified carbapenem inactivation methods (mCIMs) recommended by the CLSI for detecting carbapenemase production have not been applicable for Acinetobacter baumannii. We evaluated the influence of matrices used in mCIMs and CIMTris on the stability of the disks for detecting carbapenemase producers and suggested optimal mCIM conditions for ...
Vu TN, Byun JH, D'Souza R, Pinto NA, Nguyen LP, Yong D, Chong Y.   +6 more
europepmc   +5 more sources

Evaluation of modified carbapenem inactivation method for suspected carbapenemase among Enterobacteriaceae clinical isolates. [PDF]

Oncotarget, 2018
Modified carbapenem inactivation method (mCIM) testing was currently recommended by Clinical and Laboratory Standards Institute (CLSI) for detection of carbapenemase among Enterobacteriaceae clinical isolates. In this study, a panel of 145 clinical strains were collected for evaluating the mCIM for detection of carbapenemase.
Yu B, Dong D, Wang M, Guo Y, Yin D, Hu F.   +5 more
europepmc   +4 more sources

Application of Modified Carbapenem Inactivation Method and Its Derivative Tests for the Detection of Carbapenemase-Producing Aeromonas

Infection and Drug Resistance, 2021
Yunying Wang,1 Hui Liu,2 Lijun Zhang,1 Bin Sun1 1Department of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Blood Transfusion, The First Affiliated Hospital of ...
Wang Y, Liu H, Zhang L, Sun B
doaj   +2 more sources

An improved carbapenem inactivation method, CIMTrisII, for carbapenemase production by Gram-negative pathogens

Journal of Medical Microbiology, 2019
The modified carbapenem inactivation method (mCIM) is a simple phenotypic screening method for detecting carbapenemase production by Enterobacteriaceae and Pseudomonas aeruginosa. We recently developed another modified carbapenem inactivation method (CIMTris), in which carbapenemase is extracted from bacteria with Tris-HCl buffer, to detect ...
Kohei, Uechi, Tatsuya, Tada, Kyoko, Kuwahara-Arai, Jun-Ichiro, Sekiguchi, Izumi, Yanagisawa, Takaaki, Tome, Isamu, Nakasone, Shiro, Maeda, San, Mya, Khin Nyein, Zan, Htay Htay, Tin, Teruo, Kirikae, Jiro, Fujita   +12 more
openaire   +4 more sources

Genetic basis of carbapenem-resistant clinical Serratia marcescens in Japan

Journal of Global Antimicrobial Resistance
Objective: To investigate the genetic basis of carbapenem resistance in clinical Serratia marcescens isolates collected from patients in Japan between 1994 and 2016. A total of 5135 clinical isolates of S. marcescens were recovered from different medical
Hazim O. Khalifa, Shizuo Kayama, Mohammed Elbediwi, Liansheng Yu, Wataru Hayashi, Yo Sugawara, Mohamed-Yousif Ibrahim Mohamed, Hazem Ramadan, Ihab Habib, Tetsuya Matsumoto, Motoyuki Sugai   +10 more
doaj   +2 more sources

Closing the Gap Between Phenotypic and Genotypic Detection of Carbapenem Resistant Enterobacteriaceae by New Modified Carbapenem Inactivation Method [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Carbapenems have become one of the last resort of antimicrobials. But in last few years, Carbapenem Resistant Enterobacteriaceae (CRE) have been reported worldwide.
Satyajeet K Pawar, Shivaji T Mohite, Kailas D Datkhile, Madhavi N Patil, Pratik P Durgawale, Satish R Patil   +5 more
doaj   +2 more sources

Evaluation of Modified Rapid Carbapenem Inactivation Method (mrCIM) Combined with Rapid EDTA-Modified Carbapenem Inactivation Method (reCIM) to Detect Carbapenemase and Distinguish Metallo-Carbapenemase in Enterobacteriaceae Within Four Hours

Infection and Drug Resistance, 2020
Qiang Wei, Jide Sun, Zhu Wang, Li Yan, Chuanming Zhang, Xiuyu Xu Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Xiuyu XuDepartment of Laboratory
Wei Q, Sun J, Wang Z, Yan L, Zhang C, Xu X   +5 more
doaj   +2 more sources

Performance of seven carbapenemase detection assays in Pseudomonas aeruginosa across different epidemiological settings: a multicenter cross-sectional study [PDF]

Journal of Clinical Microbiology
The detection of carbapenemases in Pseudomonas aeruginosa remains challenging due to a great variety of other resistance mechanisms, and most laboratories, therefore, do not test for them.
Lukas Schaffarczyk, Rebekka Laufenberg, Timo J. B. van Eldijk, Niels Pfennigwerth, Sören Gatermann, Axel Hamprecht   +5 more
doaj   +2 more sources

EDTA-Modified Carbapenem Inactivation Method: a Phenotypic Method for Detecting Metallo-β-Lactamase-Producing Enterobacteriaceae. [PDF]

J Clin Microbiol, 2019
The increase in the prevalence and impact of infections caused by carbapenemase-producing Enterobacteriaceae is a global health concern. Therefore, rapid and accurate methods to detect these organisms in any clinical microbiology laboratory, including those in resource-limited settings, are essential to prevent and ...
Sfeir MM, Hayden JA, Fauntleroy KA, Mazur C, Johnson JK, Simner PJ, Das S, Satlin MJ, Jenkins SG, Westblade LF.   +9 more
europepmc   +4 more sources

Conventional and Real-Time PCR Targeting bla_OXA Genes as Reliable Methods for a Rapid Detection of Carbapenem-Resistant Acinetobacter baumannii Clinical Strains

Antibiotics, 2022
Multidrug-resistant Acinetobacter baumannii, particularly those producing carbapenemases, are spread worldwide. A reliable detection of carbapenemases is essential to choose the appropriate antimicrobial therapy and, consequently, prevent the ...
Dagmara Depka, Agnieszka Mikucka, Tomasz Bogiel, Mateusz Rzepka, Patryk Zawadka, Eugenia Gospodarek-Komkowska   +5 more
doaj   +2 more sources