Results 1 to 10 of about 13,027,602 (171)

A Modified Carbapenem Inactivation Method, CIMTris, for Carbapenemase Production in Acinetobacter and Pseudomonas Species. [PDF]

J Clin Microbiol, 2017
ABSTRACT The carbapenem inactivation method (CIM) and modified CIM (mCIM) are simple and economical phenotypic screening methods for detecting carbapenemase production in Gram-negative bacteria. Although the mCIM has been recommended by the Clinical and Laboratory Standards Institute, both the CIM and mCIM have limitations.
Uechi K, Tada T, Shimada K, Kuwahara-Arai K, Arakaki M, Tome T, Nakasone I, Maeda S, Kirikae T, Fujita J.   +9 more
europepmc   +7 more sources

Modified Carbapenem Inactivation Method for Phenotypic Detection of Carbapenemase Production among Enterobacteriaceae. [PDF]

J Clin Microbiol, 2017
ABSTRACT The ability of clinical microbiology laboratories to reliably detect carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important element of the effort to prevent and contain the spread of these pathogens and an integral part of antimicrobial stewardship.
Pierce VM, Simner PJ, Lonsway DR, Roe-Carpenter DE, Johnson JK, Brasso WB, Bobenchik AM, Lockett ZC, Charnot-Katsikas A, Ferraro MJ, Thomson RB, Jenkins SG, Limbago BM, Das S.   +13 more
europepmc   +5 more sources

Adjustment of Modified Carbapenem Inactivation Method Conditions for Rapid Detection of Carbapenemase-Producing Acinetobacter baumannii. [PDF]

Ann Lab Med, 2020
The existing modified carbapenem inactivation methods (mCIMs) recommended by the CLSI for detecting carbapenemase production have not been applicable for Acinetobacter baumannii. We evaluated the influence of matrices used in mCIMs and CIMTris on the stability of the disks for detecting carbapenemase producers and suggested optimal mCIM conditions for ...
Vu TN, Byun JH, D'Souza R, Pinto NA, Nguyen LP, Yong D, Chong Y.   +6 more
europepmc   +7 more sources

Variability of reagents matters—enhancements to the CLSI modified carbapenem inactivation method outside the United States to improve accuracy [PDF]

Journal of Clinical Microbiology
Sweety Singh, Shaoli Basu, Shahzad Mirza, Rajesh Karyakarte, Camilla Rodrigues, Yehudit Bergman, Mrunmayi Naik, Bharat Randive, Emily Jacobs, Anushruti Gupta, Matthew L. Robinson, Patricia J. Simner   +11 more
doaj   +4 more sources

Use of the Combined Modified Carbapenem Inactivation Method and EDTA-modified Carbapenem Inactivation Method for Detection of Carbapenemase-Producing Enterobacteriaceae Causing Ventilator-associated Respiratory Infections

Journal of Pure and Applied Microbiology, 2022
There is an alarming rise in carbapenem-resistant Enterobacteriaceae (CRE) causing nosocomial infections such as ventilator-associated respiratory infections (VARIs).
Nupur Koul, Barnali Kakati, Sonika Agarwal   +2 more
doaj   +2 more sources

Application of Modified Carbapenem Inactivation Method and Its Derivative Tests for the Detection of Carbapenemase-Producing Aeromonas. [PDF]

Infect Drug Resist, 2021
Infection and transmission of carbapenem-resistant Aeromonas is a serious threat to public health. Rapid and accurate detection carbapenem-resistant of these organisms is essential for reasonable treatment and infection control. This study aimed to find a simple and effective method to detect carbapenem-resistant phenotype in Aeromonas.A total of 131 ...
Wang Y, Liu H, Zhang L, Sun B.
europepmc   +6 more sources

Rapid Detection and Characterization of Carbapenemases in Enterobacterales with a New Modified Carbapenem Inactivation Method, mCIMplus. [PDF]

J Clin Microbiol, 2020
The worldwide emergence and spread of antimicrobial resistance in Gram-negative bacteria are severely limiting therapeutic options and thus constitute a major public health threat. The timely accurate detection of carbapenemase producers and the determination of carbapenemase class according to the Ambler classification can guide antimicrobial therapy ...
Petit M, Caméléna F, Cointe A, Poncin T, Merimèche M, Bonacorsi S, Birgy A, Berçot B.   +7 more
europepmc   +4 more sources

Modified Carbapenem Inactivation Method and Ethylenediaminetetraacetic Acid (EDTA)-Carbapenem Inactivation Method for Detection of Carbapenemase-Producing Enterobacterales and Pseudomonas aeruginosa. [PDF]

Cureus
The rising incidence of carbapenem resistance in Enterobacterales and Pseudomonas aeruginosa is a concern. Since carbapenemase production is the primary resistance mechanism, detecting and identifying the genes responsible for it is crucial to effectively monitor its spread.This study aims to detect positivity for the modified carbapenem inactivation ...
Verma G, Singh N, Smriti S, Panda SS, Pattnaik D, Tripathy S, Praharaj AK, Patro ARK.   +7 more
europepmc   +3 more sources

Evaluation of Modified Rapid Carbapenem Inactivation Method (mrCIM) Combined with Rapid EDTA-Modified Carbapenem Inactivation Method (reCIM) to Detect Carbapenemase and Distinguish Metallo-Carbapenemase in Enterobacteriaceae Within Four Hours. [PDF]

Infect Drug Resist, 2020
To develop a rapid EDTA-modified carbapenem inactivation method (reCIM) combined with modified rapid carbapenem inactivation method (mrCIM) to detect carbapenemase and distinguish metallo-β-lactamases from carbapenemases in Enterobacteriaceae in 4 hrs.The sensitivities and specificities of mrCIM and reCIM were retrospectively evaluated in 247 ...
Wei Q, Sun J, Wang Z, Yan L, Zhang C, Xu X.   +5 more
europepmc   +5 more sources

Evaluation of the EDTA-Modified Carbapenem Inactivation Method for Detecting Metallo-β-Lactamase-Producing Pseudomonas aeruginosa. [PDF]

J Clin Microbiol, 2020
The prevalence of carbapenem-resistant Pseudomonas aeruginosa is increasing. Identification of carbapenemase-producing P. aeruginosa will have therapeutic, epidemiological, and infection control implications.
Gill CM, Lasko MJ, Asempa TE, Nicolau DP.   +3 more
europepmc   +4 more sources