Results 41 to 50 of about 38,351 (178)

The Immaculate Carbapenemase Study

, 2017
Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the
Kenneth S. Thomson
core   +1 more source

Rapid detection of carbapenemase-producing Pseudomonas spp. using the NitroSpeed-Carba NP test

, 2021
The NitroSpeed-Carba NP test was used to rapidly detect and discriminate between the different types of carbapenemases (classes A, B, and D) within 30 minutes among a collection of 202 Pseudomonas sp. strains (mostly Pseudomonas aeruginosa).
Sadek, M., Poirel, L., Nordmann, P., Sadek, Mustafa, Nordmann, Patrice, Poirel, Laurent, Laurent Poirel, Mustafa Sadek, Patrice Nordmann   +8 more
core   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

Veterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan, Nicola Williams, Jenny Llewelyn, Sam Haldenby, Gina Pinchbeck, Dorina Timofte   +5 more
wiley   +1 more source

A nitrocefin disc supplemented with ertapenem for rapid screening of carbapenemase-producing Enterobacteriaceae [PDF]

, 2018
Reliable, simple and rapid methods for laboratory detection of carbapenemases are important for an appropriate antibiotic administration. A nitrocefin disc containing ertapenem for rapid screening of carbapenemase production among Enterobacteriaceae is ...
Teethaisong, Y, Nakouti, I, Hobbs, G, Evans, K, Eumkeb, G, Ismini Nakouti, Glyn Hobbs, Griangsak Eumkeb, Katie Evans, Yothin Teethaisong   +9 more
core   +1 more source

Development and Application of a Rapid 23S rRNA‐Targeted Reverse Transcription Quantitative PCR System for the Detection and Quantification of Enterobacterales

Microbiology and Immunology, EarlyView.
ABSTRACT Bacteria belonging to the family Enterobacteriaceae occur as commensals or pathogens in humans. The increasing prevalence of multidrug‐resistant bacteria has raised global concern. Following the reclassification of Enterobacteriaceae species into the order Enterobacterales in 2016.
Satomi Atobe, Mai Hane, Akira Takahashi, Yukiko Kado, Rie Date, Shuta Yamamoto, Takashi Asahara   +6 more
wiley   +1 more source

Phenotypic and genotypic characterization of carbapenem resistant Klebsiella pneumoniae clinical isolates from Damietta, Egypt

BMC Microbiology
Background The notable emergence of carbapenemase production is a critical problem threatening human health worldwide. Hence, this study aimed to monitor the prevalence of carbapenemase-producing Klebsiella pneumoniae in Damietta, Egypt.
Mohamed I. Abou-Dobara, Ahmed K. A. El-Sayed, Radwa N. Elmaghalawy, Hazem H. Saleh   +3 more
doaj   +1 more source

ESBL and carbapenemase harboring isolates.

, 2016
ESBL and carbapenemase harboring isolates.
Michaela Lipp (3331206), Bettina Folli (3331212), Gernot Zarfel (3331197), Rita Baumert (3331200), Herbert Galler (3331203), Andreas H. Farnleitner (1298766), Josefa Luxner (3331215), Clemens Kittinger (3331194), Andrea J. Grisold (611885), Alexander Kirschner (1955326), Melanie Weissenbacher (3331209)   +10 more
core   +1 more source

MALDI-ToF basierte Frühdiagnostik Carbapenemase-positiver gramnegativer Bakterien [PDF]

, 2017
Einleitung: Die zunehmende Ausbreitung von multiresistenten Bakterien ist eine globale Herausforderung und bedarf zwingend schneller, sensitiver und einfach durchführbarer Diagnostik.
Bauer, Kim Jens
core   +1 more source