Results 61 to 70 of about 33,486 (230)

In vitro activity of cefiderocol against carbapenemase-producing and meropenem-non-susceptible Gram-negative bacteria collected in the Japan Antimicrobial Resistant Bacterial Surveillance

Journal of Global Antimicrobial Resistance
Objectives: The treatment options available for infections caused by multidrug-resistant Gram-negative pathogens are often limited. Cefiderocol (CFDC) is a novel siderophore cephalosporin that exhibits activity against these pathogens.
Shizuo Kayama, Sayoko Kawakami, Kohei Kondo, Norikazu Kitamura, Liansheng Yu, Wataru Hayashi, Koji Yahara, Yo Sugawara, Motoyuki Sugai   +8 more
doaj   +1 more source

Carbapenemase-Producing Enterobacteriaceae in Spain in 2012 [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1.
Oteo-Iglesias, Jesus, Saez, David, Bautista, Veronica, Fernandez-Romero, Sara, Hernández-Molina, Juan Manuel, Perez-Vazquez, Maria, Aracil, Belen, Campos, Jose   +7 more
openaire   +3 more sources

The carbapenemase threat in the animal world: the wrong culprit [PDF]

, 2014
We read with great interest two recent publications dealing with the same topic, i.e. the public health risk related to the occurrence of acquired carbapenemase-producing Gram-negative species in the animal world and the environment.1,2 Woodford et al.1 ...
Perreten, Vincent, Nordmann, Patrice, Poirel, Laurent, Stephan, Roger   +3 more
core   +1 more source

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

Food Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento, Luan Amaral Alexandre, Cynthia Farias Manassi, Alice Cristina da Silva, Luísa Aimée Schmitt Lobe, Gustavo Rocha, Mateus Rocha Ribas, Victor Wolleck, Gabriele Caroline Gottschalk de Abreu, Alessandra Valéria Vortmann, Sheila Mello da Silveira, Rodrigo Barcellos Hoff, Jussara Kasuko Palmeiro, Silvani Verruck   +13 more
wiley   +1 more source

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, EarlyView.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

An Xpert screen to identify carbapenemases

Indian Journal of Medical Microbiology, 2016
To prevent the spread of carbapenemases-producing Enterobacteriaceae (CPE) active surveillance, contact isolation and cohorting infected patients should be practiced. Rectal swabs for the Xpert MDRO-assay of 32 patients were included. 71.85% were positive for targets incorporated into the MDRO-assay; whereas 28% were phenotypically not CRE and Xpert ...
Mubin, Kazi, Chaitali, Nikam, Anjali, Shetty, Camilla, Rodrigues   +3 more
openaire   +2 more sources

Evaluation of the AID carbapenemase line probe assay for rapid detection and identification of carbapenemase genes in Gram-negative bacilli [PDF]

, 2021
Objectives: This study evaluated the AID carbapenemase line probe assay (LPA) for the detection and identification of carbapenem resistance genes in Enterobacteriaceae and other Gram-negative bacilli (GNB) using bacterial cultures and DNA extracts ...
Bloemberg, Guido V., Tedrup, Jan, Meijerink, Carla, Durer, Elena, Ritter, Claudia, Keller, Peter M., Hombach, Michael, Braun-Kiewnick, Andrea   +7 more
core  

Wide spread of carbapenemase-producing bacterial isolates in a Nigerian environment

Journal of Global Antimicrobial Resistance, 2020
Objectives: The presence of carbapenemase-producing bacterial isolates is found not only in hospital and community settings but also in the environment.
Christophe Le Terrier, Amandine Masseron, Nkolika Stella Uwaezuoke, Chinagozi P. Edwin, Agantem E. Ekuma, Folake Olugbeminiyi, Shuwaram Shettima, Simon Ushie, Laurent Poirel, Patrice Nordmann   +9 more
doaj   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

A Patient With Multiple Carbapenemase Producers Including an Unusual Citrobacter sedlakii Hosting an IncC blaNDM-1- and armA-carrying Plasmid [PDF]

, 2021
Background. Patients colonized with multiple species of carbapenemase-producing Enterobacterales (CPE) are increasingly observed. This phenomenon can be due to the high local prevalence of these pathogens, the presence of important host risk factors, and
Moser, Aline I., Endimiani, Andrea, Keller, Peter M., Campos-Madueno, Edgar I., Nordmann, Patrice, Poirel, Laurent   +5 more
core   +1 more source