Results 61 to 70 of about 24,598 (183)

Evaluation of a modified meropenem hydrolysis assay on a large cohort of KPC and VIM carbapenemase-producing Enterobacteriaceae. [PDF]

PLoS ONE, 2017
Carbapenem-resistant Enterobacteriaceae (CRE) have spread globally and represent a serious and growing threat to public health. The introduction of rapid and sensitive methods for the detection of carbapenemase-producing bacteria is of increasing ...
Adriana Calderaro, Mirko Buttrini, Maddalena Piergianni, Sara Montecchini, Monica Martinelli, Silvia Covan, Giovanna Piccolo, Maria Cristina Medici, Maria Cristina Arcangeletti, Carlo Chezzi, Flora De Conto   +10 more
doaj   +1 more source

Use of Ancillary Carbapenemase Tests To Improve Specificity of Phenotypic Definitions for Carbapenemase-Producing Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 2017
ABSTRACT Carbapenemase-producing Enterobacteriaceae (CPE) are a significant threat to public health. In 2015, CDC revised the surveillance definition for CPE to include all Enterobacteriaceae resistant to any carbapenem tested.
Shelley A, Miller, Janet A, Hindler, Angelo, Chengcuenca, Romney M, Humphries   +3 more
openaire   +2 more sources

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba, Jubilee Andrew, Donald Fernandes   +2 more
wiley   +1 more source

Frailty‐associated outcomes in geriatric emergency medicine ward patients: A retrospective cohort study informing program development

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Frail elderly patients require more interventions, and longer hospitalizations due to their complex health needs. The Emergency Medicine Ward (EMW) aims to provide acute care for patients with low‐acuity medical issues, often using a multidisciplinary approach for holistic care and discharge.
Tsz Kiu Chan, Man Ting Lau, Ka In Chan, Yuen Wa Ip, Wing Yuk Chan, Sze Yan Pui, Ying Ying Lam, Shing Ko, Oi Fung Wong, Sau Lai Chan, Candy Leung, Tsz Wah Patrick So, Po Fan Paul Chui, Wai Bik Geraldine Ng   +13 more
wiley   +1 more source

Comparison of Modified Carbapenem Inactivation Method (mCIM) with Novel Rapid Carbapenemase Detection Method (rCDM) for Detection of Carbapenemase-Producing Organisms from Clinical Isolates

Pakistan Armed Forces Medical Journal
Objective: To determine the diagnostic accuracy of rapid Carbapenemase detection method (rCDM) for the detection of Carbapenemase-producing organisms, keeping the modified carbapenem inactivation method (mCIM) as the reference method Study Design ...
Asad Zafar, Irfan Ali Mirza, Sakeenah Hussain Naqvi, Anam Imtiaz, Adeel Gardezi, Rabia Sajjad   +5 more
doaj   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 8, Page 1478-1491, August 2026.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque, Md. Shaminur Rahman, Munawar Sultana, Anowara Begum   +3 more
wiley   +1 more source

Emergence of Ceftazidime‐Avibactam‐Induced KPC Variants (KPC‐25/127) in Intracranial Infection and Implications for Clinical Management

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Novel KPC‐25 and first‐reported KPC‐127 sequentially evolved in one patient under CAZ‐AVI pressure, distinct mutations remodel enzyme activity to drive differential multidrug resistance. ABSTRACT The emergence of novel Klebsiella pneumoniae carbapenemase (KPC) variants contributing to clinical treatment failure poses a substantial threat to public ...
Ke Lei, Ying Tian, Chaoliang Xiong, Jing Lei, Dong Chen, Xiangni Bai, Mohd H. Abdul‐Aziz, Jiao Xie, Zeshi Liu   +8 more
wiley   +1 more source

Investigating the relationship between carbapenemase production and biofilm formation in Klebsiella pneumoniae clinical isolates

BMC Research Notes
Objective Carbapenemase production and biofilm formation in K. pneumoniae are crucial factors influencing the pathogenicity and antibiotic resistance of this bacterium.
Nora M. El Naggar, Riham M. Shawky, Fathy M. E. Serry, Mohamed Emara   +3 more
doaj   +1 more source

Detection of OXA‐23 Among Carbapenem‐Resistant Acinetobacter baumannii Isolated From Intensive Care Units of a Tertiary Care Hospital in Pakistan

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Graphical Abstract of the Experimental Workflow for CRAB Isolate Characterization. ABSTRACT Carbapenem‐resistant Acinetobacter baumannii (CRAB) has been designated a top‐priority critical pathogen by the World Health Organization, and the CDC has also classified it as a serious and immediate public health threat. The Cross‐sectional study was conducted
Hafsa Waseem, Ihsan Ullah, Shahzad Ahmad, Irfan Ali Mirza, Benish Aleem, Shazia Iqbal   +5 more
wiley   +1 more source