Results 21 to 30 of about 33,486 (230)

To Be or Not to Be an OXA-48 Carbapenemase [PDF]

Microorganisms, 2022
Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems and penicillins with very weak or almost no activity against expanded-spectrum cephalosporins, some ...
Laura Dabos, Saoussen Oueslati, Sandrine Bernabeu, Rémy A. Bonnin, Laurent Dortet, Thierry Naas   +5 more
openaire   +3 more sources

Diagnostic Performance of BD Phoenix CPO Detect Panels for Detection and Classification of Carbapenemase-Producing Gram-Negative Bacteria

Microbiology Spectrum, 2023
BD Phoenix CPO Detect panels can identify and classify carbapenemase-producing organisms (CPOs) simultaneously with antimicrobial susceptibility testing (AST) for Gram-negative bacteria.
Mika Murata, Kosuke Kosai, Norihiko Akamatsu, Yumiko Matsuyama, Mitsuharu Oda, Atsushi Wakamatsu, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara   +8 more
doaj   +1 more source

Class A carbapenemases [PDF]

Journal of Antimicrobial Chemotherapy, 2007
Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
openaire   +2 more sources

Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE)

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: To describe national trends in testing and detection of carbapenemases produced by carbapenem-resistant Enterobacterales (CRE) and associate testing with culture and facility ...
Margaret A. Fitzpatrick, Katie J. Suda, Swetha Ramanathan, Geneva Wilson, Linda Poggensee, Martin Evans, Makoto M. Jones, Christopher D. Pfeiffer, J. Stacey Klutts, Eli Perencevich, Michael Rubin, Charlesnika T. Evans, for the QUERI CARRIAGE Program   +12 more
doaj   +1 more source

Carbapenemase-Producing Enterobacteriaceae [PDF]

Seminars in Respiratory and Critical Care Medicine, 2015
Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
openaire   +5 more sources

Detection of blaKPC and blaNDM carbapenemase genes among Klebsiella pneumoniae isolates in Addis Ababa, Ethiopia: Dominance of blaNDM.

PLoS ONE, 2022
BackgroundInfections caused by Klebsiella pneumoniae have been difficult to control because of the worldwide emergence of carbapenem-resistant isolates mainly due to carbapenemase production. Information regarding carbapenemase-producing K. pneumoniae is
Tewachew Awoke, Brhanu Teka, Abraham Aseffa, Shemse Sebre, Aminu Seman, Biruk Yeshitela, Tamrat Abebe, Adane Mihret   +7 more
doaj   +1 more source

A Longitudinal Nine-Year Study of the Molecular Epidemiology of Carbapenemase-Producing Enterobacterales Isolated From a Regional Hospital in Taiwan: Predominance of Carbapenemase KPC-2 and OXA-48

Frontiers in Microbiology, 2022
Enterobacterales clinical isolates are now being resistant to clinically achievable concentrations of most commonly used antibiotics that makes treatment of hospitalized patients very challenging.
Tran Thi Thuy Duong, Ya-Min Tsai, Li-Li Wen, Hui-Chuan Chiu, Pek Kee Chen, Tran Thi Dieu Thuy, Pei-Yun Kuo, Jazon Harl Hidrosollo, Shining Wang, Yen-Zhen Zhang, Wei-Hung Lin, Wei-Hung Lin, Ming-Cheng Wang, Ming-Cheng Wang, Cheng-Yen Kao   +14 more
doaj   +1 more source

Evaluation of Phenotypic Carbapenemase Production in blaOXA-48 positive K. pneumoniae Isolates by Modified Hodge and Carbapenemase Inactivation Tests [PDF]

, 2020
Aim:In recent years, increasing colonization rates of K. pneumoniae in patients with immunosuppression, long hospital stay, invasive devices and treated with broad spectrum antibiotics lead to resistant infections.
E. Deniz BAYRAM, Özlem Yüksel ERGİN, Reyhan YİŞ   +2 more
core   +1 more source

Carbapenemase genes and mortality in patients with carbapenem-resistant Enterobacterales, Atlanta, Georgia, 2011–2020

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Carbapenemase genes in carbapenem-resistant Enterobacterales (CP-CRE) may be transmitted between patients and bacteria. Reported rates of carbapenemase genes vary widely, and it is unclear whether having a carbapenemase gene portends worse ...
Lucy Witt, Ahmed Babike, Gillian Smith, Sarah Satola, Mary Elizabeth Sexton, Jesse Jacob   +5 more
doaj   +1 more source

OXA-type carbapenemases [PDF]

Journal of Antimicrobial Chemotherapy, 2006
In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire   +2 more sources