Molecular carbapenem-resistance testing, such as for the presence of carbapenemases genes, is commonly implemented for the detection of carbapenemase-producing Enterobacterales. Carbapenemase-producing P.
Christian M Gill +2 more
exaly +3 more sources
The Immaculate Carbapenemase Study [PDF]
ABSTRACT Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the Journal of Clinical Microbiology , Karlowsky
Kenneth S. Thomson
openaire +3 more sources
An improved method for rapid detection and characterization of carbapenemase-producing Enterobacterales directly from positive blood cultures: dBLIMplus [PDF]
In this study, a new phenotypic method “dBLIMplus” performed by using combination disks for both detection of carbapenemase activity and determination of the carbapenemase enzyme of carbapenemase-producing Enterobacterales strains from positive blood ...
Tugba Ayvalik Ruzgarkesen +3 more
doaj +2 more sources
Multidrug resistance has been increasing world wide amongst most microrganisms, and adding to increased rate of both hospital and community acquired infections. Of all resistance mechanisms the alarming spread of carbapenemase producers is most worrisome
Iva Chandola +3 more
doaj +2 more sources
The shift from “MIC-Only” back to carbapenemase testing among carbapenem-resistant Enterobacterales: what clinical laboratories need to know about updated CLSI guidance [PDF]
Carbapenem-resistant organisms (CROs) pose a major threat to global health due to limited therapeutic options and their capacity for rapid dissemination.
Patricia J. Simner
doaj +2 more sources
Phenotypic and genotypic characterization of carbapenem resistant Klebsiella pneumoniae clinical isolates from Damietta, Egypt [PDF]
Background The notable emergence of carbapenemase production is a critical problem threatening human health worldwide. Hence, this study aimed to monitor the prevalence of carbapenemase-producing Klebsiella pneumoniae in Damietta, Egypt.
Mohamed I. Abou-Dobara +3 more
doaj +2 more sources
Screening for carbapenemase-producing Enterobacterales is a necessity for hospitals serving high-risk patient populations. Detection methods often incorporate the modified carbapenemase inactivation method (mCIM) test to verify carbapenemase production ...
D. Garrett Brown +6 more
doaj +3 more sources
Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae are the most common Gram-negative bacillus (GNB) isolates from clinical samples.
Rajal Dave, Abhijeet Joshi
doaj +3 more sources
Can phenotypic methods accurately identify carbapenemase production in Morganellaceae?
AIM: We aimed to evaluate and compare the performance of two chromagenic media (CM) and the carbapenem-inactivation method (CIM) in identifying carbapenemase production in the Morganellaceae members.
Çisem Karaoğlu +3 more
doaj +2 more sources
Multicenter Analytical Performance Evaluation of the BD Phoenix NMIC-461 Panel for Carbapenemase Classification and Antimicrobial Susceptibility Testing of Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. [PDF]
Objectives: To evaluate the capability of the BD Phoenix NMIC-461 panel in the detection and classification of carbapenemase production and antimicrobial susceptibility testing of 10 antimicrobial agents among Enterobacterales, Pseudomonas aeruginosa ...
Jingjia Zhang +10 more
doaj +2 more sources

