Results 11 to 20 of about 24,598 (183)
Journal of Clinical MicrobiologyScreening for carbapenemase-producing Enterobacterales is a necessity for hospitals serving high-risk patient populations. Detection methods often incorporate the modified carbapenemase inactivation method (mCIM) test to verify carbapenemase production ...
D. Garrett Brown +6 more
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To Be or Not to Be an OXA-48 Carbapenemase [PDF]
Microorganisms, 2022 Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems and penicillins with very weak or almost no activity against expanded-spectrum cephalosporins, some ...
Laura Dabos +5 more
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Journal of Antimicrobial Chemotherapy, 2007 Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
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Carbapenemase-Producing Enterobacteriaceae [PDF]
Seminars in Respiratory and Critical Care Medicine, 2015 Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
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Journal of Antimicrobial Chemotherapy, 2006 In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
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Development of a Two Triplex Real-Time Polymerase Chain Reaction for Rapid Detection of Six Carbapenemase Genes in Enterobacteriaceae [PDF]
Osong Public Health and Research Perspectives, 2020 Objectives Carbapenem resistance is a serious clinical and public health threat. Carbapenemase can confer carbapenem resistance, and most carbapenemase genes are plasmid encoded so resistance can easily spread.
Ji Ae Choi +3 more
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Nigerian Postgraduate Medical Journal, 2015 Aims and Objectives: Carbapenemase production among clinical isolates of Enterobacteriaceae has been widely reported with prevalence rates ranging from between 2.8% and 53.6%. The aim of this study was to assess the prevalence of carbapenemase production
O O Oduyebo +3 more
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Rapid detection of carbapenemases and ESKAPEEc bacteria [PDF]
Archives of the Balkan Medical Union, 2021 Introduction. Carbapenems have been the ultimate antibiotics for the treatment of infections caused by multidrug-resistant bacteria. However, recently, carbapenems-resistant bacteria have emerged significantly. The objective of the study was the identification of ESKAPEEc bacteria and rapid detection of carbapenemase production.
Aydoğan, Okan +1 more
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Comparation of Phenotypic and Genotypic Profile of Carbapenemase Producing Escherichia coli
Folia Medica Indonesiana, 2018 Carbapenemase-producing Escherichia coli (E. coli) has caused trouble in therapeutic antibiotic selection. Carbapenemase screening procedure in laboratories is usually based on inacurate semi-automatic system.
Silvia Sutandhio +5 more
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Antimicrobial Stewardship & Healthcare Epidemiology, 2023 Objectives: The identification and classification of carbapenemases are meaningful in clinical treatment, epidemiology, and multidrug-resistant bacteria control.
Tuan Huynh, Loan Luong
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