Results 11 to 20 of about 36,890 (230)

Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE)

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: To describe national trends in testing and detection of carbapenemases produced by carbapenem-resistant Enterobacterales (CRE) and associate testing with culture and facility ...
Margaret A. Fitzpatrick, Katie J. Suda, Swetha Ramanathan, Geneva Wilson, Linda Poggensee, Martin Evans, Makoto M. Jones, Christopher D. Pfeiffer, J. Stacey Klutts, Eli Perencevich, Michael Rubin, Charlesnika T. Evans, for the QUERI CARRIAGE Program   +12 more
doaj   +1 more source

Detection of blaKPC and blaNDM carbapenemase genes among Klebsiella pneumoniae isolates in Addis Ababa, Ethiopia: Dominance of blaNDM.

PLoS ONE, 2022
BackgroundInfections caused by Klebsiella pneumoniae have been difficult to control because of the worldwide emergence of carbapenem-resistant isolates mainly due to carbapenemase production. Information regarding carbapenemase-producing K. pneumoniae is
Tewachew Awoke, Brhanu Teka, Abraham Aseffa, Shemse Sebre, Aminu Seman, Biruk Yeshitela, Tamrat Abebe, Adane Mihret   +7 more
doaj   +1 more source

A Longitudinal Nine-Year Study of the Molecular Epidemiology of Carbapenemase-Producing Enterobacterales Isolated From a Regional Hospital in Taiwan: Predominance of Carbapenemase KPC-2 and OXA-48

Frontiers in Microbiology, 2022
Enterobacterales clinical isolates are now being resistant to clinically achievable concentrations of most commonly used antibiotics that makes treatment of hospitalized patients very challenging.
Tran Thi Thuy Duong, Ya-Min Tsai, Li-Li Wen, Hui-Chuan Chiu, Pek Kee Chen, Tran Thi Dieu Thuy, Pei-Yun Kuo, Jazon Harl Hidrosollo, Shining Wang, Yen-Zhen Zhang, Wei-Hung Lin, Wei-Hung Lin, Ming-Cheng Wang, Ming-Cheng Wang, Cheng-Yen Kao   +14 more
doaj   +1 more source

Evaluation of Phenotypic Carbapenemase Production in blaOXA-48 positive K. pneumoniae Isolates by Modified Hodge and Carbapenemase Inactivation Tests [PDF]

, 2020
Aim:In recent years, increasing colonization rates of K. pneumoniae in patients with immunosuppression, long hospital stay, invasive devices and treated with broad spectrum antibiotics lead to resistant infections.
E. Deniz BAYRAM, Özlem Yüksel ERGİN, Reyhan YİŞ   +2 more
core   +1 more source

A Four-Center Study on the Activity of Aztreonam and Aztreonam-Avibactam Combination Against Clinical Isolates of Gram-Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β-Lactamases. [PDF]

APMIS
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Ceviz Gİ, Mirza HC, Güçlü AÜ, Şanlı ÖÖ, Azap ÖK, Sancak B, İştar EH, Başustaoğlu A.   +7 more
europepmc   +2 more sources

OXA-type carbapenemases [PDF]

Journal of Antimicrobial Chemotherapy, 2006
In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire   +2 more sources

Carbapenemase genes and mortality in patients with carbapenem-resistant Enterobacterales, Atlanta, Georgia, 2011–2020

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Carbapenemase genes in carbapenem-resistant Enterobacterales (CP-CRE) may be transmitted between patients and bacteria. Reported rates of carbapenemase genes vary widely, and it is unclear whether having a carbapenemase gene portends worse ...
Lucy Witt, Ahmed Babike, Gillian Smith, Sarah Satola, Mary Elizabeth Sexton, Jesse Jacob   +5 more
doaj   +1 more source

Development of a Two Triplex Real-Time Polymerase Chain Reaction for Rapid Detection of Six Carbapenemase Genes in Enterobacteriaceae [PDF]

Osong Public Health and Research Perspectives, 2020
Objectives Carbapenem resistance is a serious clinical and public health threat. Carbapenemase can confer carbapenem resistance, and most carbapenemase genes are plasmid encoded so resistance can easily spread.
Ji Ae Choi, Song Mee Bae, Jung Wook Kim, Kwang Jun Lee   +3 more
doaj   +1 more source

Phenotypic determination of carbapenemase producing enterobacteriaceae isolates from clinical specimens at a tertiary hospital in Lagos, Nigeria

Nigerian Postgraduate Medical Journal, 2015
Aims and Objectives: Carbapenemase production among clinical isolates of Enterobacteriaceae has been widely reported with prevalence rates ranging from between 2.8% and 53.6%. The aim of this study was to assess the prevalence of carbapenemase production
O O Oduyebo, O M Falayi, P Oshun, A O Ettu   +3 more
doaj   +1 more source

A Four-Hour Carbapenem Inactivation Method (CIMB.S) Using Bacillus stearothermophilus as Indicator Strain

Frontiers in Medicine, 2020
Objectives: There is an urgent need for accurate and fast diagnostic tests to identify carbapenemase-producing bacteria. Here we used Bacillus stearothermophilus as an indicator strain in the format of the carbapenem inactivation method (CIM) procedure ...
Ze-Hua Cui, Ze-Hua Cui, Ling Jia, Ling Jia, Lu Han, Lu Han, Tian Tang, Tian Tang, Zi-Xing Zhong, Zi-Xing Zhong, Liang-Xing Fang, Liang-Xing Fang, Wei-Na Ni, Wei-Na Ni, Min-Ge Wang, Min-Ge Wang, Xi-Ran Wang, Xi-Ran Wang, Ya-Hong Liu, Ya-Hong Liu, Ya-Hong Liu, Xiao-Ping Liao, Xiao-Ping Liao, Xiao-Ping Liao, Jian Sun, Jian Sun, Jian Sun   +26 more
doaj   +1 more source