Results 31 to 40 of about 882,804 (137)

Neurite Outgrowth-Promoting Activity of Compounds in PC12 Cells from Sunflower Seeds

Molecules, 2020
In the current super-aging society, the establishment of methods for prevention and treatment of Alzheimer’s disease (AD) is an urgent task. One of the causes of AD is thought to be a decrease in the revel of nerve growth factor (NGF) in the brain ...
Takeru Koga, Takaiku Sakamoto, Eiji Sakuradani, Akihiro Tai   +3 more
doaj   +1 more source

β-sitosterol inhibits trimethylamine production by regulating the gut microbiota and attenuates atherosclerosis in ApoE–/– mice

Frontiers in Cardiovascular Medicine, 2022
The intestinal microbial metabolite trimethylamine (TMA), which is activated by flavin monooxygenase (FMO) to produce trimethylamine-N-oxide (TMAO), has been implicated in the pathogenesis of atherosclerosis (AS), leading to the development of ...
Weiping Wu, Wugao Liu, Huafu Wang, Wei Wang, Weihua Chu, Jing Jin   +5 more
doaj   +1 more source

Synthesis, Physical Properties, and In Vitro-Simulated Gastrointestinal Digestion of Hydrophilic β‑Sitosterol Sugar Esters

, 2022
Hydrophilic β-sitosterol sugar esters were synthesized by a two-step biocatalytic approach using β-sitosterol vinyl adipate as an intermediate. The maximum conversion (above 90%) of β-sitosterol vinyl adipate was achieved using the saccharides glucose ...
Tong Wang (87696), Ge Bai (295866), Shujing Guo (1689883), Chuanguo Ma (6240680), Jun Liu (42548), Yuyuan Hu (12999863)   +5 more
core   +1 more source

β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice

Cell Reports Medicine, 2021
Summary: Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage.
Nicolas Panayotis, Philip A. Freund, Letizia Marvaldi, Tali Shalit, Alexander Brandis, Tevie Mehlman, Michael M. Tsoory, Mike Fainzilber   +7 more
doaj   +1 more source

Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol

, 2018
Beta-sitosterol (β-SITO), a phytosterol present in many edible vegetables, has been reported to possess antineoplastic properties and cancer treatment potential.
Sinjan Choudhary (617211), Pradeep Kumar Naik (436805), Madhura Pradhan (3608507), Charu Suri (3608510), Manu Lopus (474970)   +4 more
core   +1 more source

Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice

Lipids in Health and Disease, 2019
Background The hypolipidemic effect of phytosterols has been wildely recognized, but its application is limited due to its insolubility in water and low solubility in oil.
Chuanxun Yuan, Xueru Zhang, Xue Long, Jing Jin, Risheng Jin   +4 more
doaj   +1 more source

Effects of β-sitosterol on growth, development and midgut enzymes of Helicoverpa armigera Hübner [PDF]

Archives of Biological Sciences, 2020
Helicoverpa armigera is a global agricultural pest of serious concern. Continued use of chemical insecticides as control measures has raised grave health and environment concerns, necessitating a search for botanicals as safe alternatives.
Mishra Monika, Sharma Aarti, Dagar Vinay Singh, Kumar Sarita   +3 more
doaj   +1 more source

Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis

Neural Regeneration Research
[INLINE:1] β-Sitosterol is a type of phytosterol that occurs naturally in plants. Previous studies have shown that it has anti-oxidant, anti-hyperlipidemic, anti-inflammatory, immunomodulatory, and anti-tumor effects, but it is unknown whether β ...
Xiuling Tang, Tao Yan, Saiying Wang, Qingqing Liu, Qi Yang, Yongqiang Zhang, Yujiao Li, Yumei Wu, Shuibing Liu, Yulong Ma, Le Yang   +10 more
doaj   +1 more source

In vitro and in silico Evaluation of Some Natural Molecules as Potent Glutathione Reductase Inhibitors

International Journal of Secondary Metabolite, 2020
Glutathione reductase inhibitors are very popular antimalarial and anticancer agents. In this study, in vitro inhibition effects of β-sitosterol, stigmasterol, diosgenin and jervine which containing steroidal structure were determined against glutathione
Tuba Aydin
doaj   +1 more source

Anti-atherosclerosis potential activity from Alphitobius diaperinus: a molecular docking study on NLRP3 receptor

Jurnal Ilmu Peternakan Terapan
This study aimed to analyze the potential activity anti-atherosclerosis of Alphitobius diaperinus larvae using molecular docking. The target receptor used was NLRP3, with β-sitosterol and campesterol as the test ligands, and simvastatin as the control ...
Firdaus Hasibuan, Erfan Andrianto Aritonang   +1 more
doaj   +1 more source