Results 41 to 50 of about 27,869 (185)

Anti-proliferative effect of main dietary phytosterols and \u3b2-cryptoxanthin alone or combined in human colon cancer Caco-2 cells through cytosolic Ca+2 \u2013 and oxidative stress induced apoptosis [PDF]

, 2015
\u3b2-cryptoxanthin (\u3b2-Cx) and phytosterols (Ps) have potential against different cancer types,including colon cancer. However, their combined action has not been reported so far. Human colon cancer Caco-2 cells were treated 24 h with \u3b2-Cx and/or
Attanzio, A, Barber\ue1, R, Cilla, A, Livrea, MA, Tesoriere, L   +4 more
core   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Anti-atherosclerosis potential activity from Alphitobius diaperinus: a molecular docking study on NLRP3 receptor

Jurnal Ilmu Peternakan Terapan
This study aimed to analyze the potential activity anti-atherosclerosis of Alphitobius diaperinus larvae using molecular docking. The target receptor used was NLRP3, with β-sitosterol and campesterol as the test ligands, and simvastatin as the control ...
Firdaus Hasibuan, Erfan Andrianto Aritonang   +1 more
doaj   +1 more source

Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice

Lipids in Health and Disease, 2019
Background The hypolipidemic effect of phytosterols has been wildely recognized, but its application is limited due to its insolubility in water and low solubility in oil.
Chuanxun Yuan, Xueru Zhang, Xue Long, Jing Jin, Risheng Jin   +4 more
doaj   +1 more source

In vitro and in silico Evaluation of Some Natural Molecules as Potent Glutathione Reductase Inhibitors

International Journal of Secondary Metabolite, 2020
Glutathione reductase inhibitors are very popular antimalarial and anticancer agents. In this study, in vitro inhibition effects of β-sitosterol, stigmasterol, diosgenin and jervine which containing steroidal structure were determined against glutathione
Tuba Aydin
doaj   +1 more source

Impact of Pumpkin and Carrot Flours on the Oxidative and Rheological Properties: Properties of Low‐Fat Cold‐Pressed Oil Mayonnaise

Journal of the American Oil Chemists' Society, EarlyView.
Partial substitution of sunflower oil with cold‐pressed oils (0‐20%) improves the bioactive composition, oxidative stability, and overall quality of mayonnaise while preserving emulsion stability. ABSTRACT This study investigates the effects of xanthan gum, carrot flour, and pumpkin flour on the physicochemical, rheological, and bioactive properties of
S. Gülen, D. Günal‐Köroğlu, S. Turan   +2 more
wiley   +1 more source

Increased Yield of Biotransformation of Androsta-1, 4-Dien-3, 17-Dione from Β-Sitosterol by Using Sulfobutyl Ether-Β-Cyclodextrin Complexation Technique

MATEC Web of Conferences, 2016
Substrate solubility in steroid biotransformation is critical for enhancing the biotransformation of hydrophobic compounds. In this study, the sulfobutyl ether-β-cyclodextrin (SBE-β-CD) complexation technique was used for the biotransformation of β ...
Wang Jingwen, Guan Shimin, Cai Baoguo, Zhang Shuo, Yang Shulin, Zhou Yue, Rong Shaofeng, Li Qianqian   +7 more
doaj   +1 more source

Beta-Sitosterol Facilitates GLUT4 Vesicle Fusion on the Plasma Membrane via the Activation of Rab/IRAP/Munc 18 Signaling Pathways in Diabetic Gastrocnemius Muscle of Adult Male Rats

Bioinorganic Chemistry and Applications, 2022
Nutritional overload in the form of high-fat and nonglycolysis sugar intake contributes towards the accelerated creation of reactive oxygen species (ROS), hyperglycemia, and dyslipidemia.
JinJin Pei, Monisha Prasad, Ghada Mohamed Helal, Mohamed El-Sherbiny, Dalia Mahmoud Abdelmonem Elsherbini, Ponnulakshmi Rajagopal, Chella Perumal Palanisamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Krishna Mohan Surapaneni   +9 more
doaj   +1 more source

β-Sitosterol Ameliorates Endometrium Receptivity in PCOS-Like Mice: The Mediation of Gut Microbiota

Frontiers in Nutrition, 2021
Background: Polycystic ovary syndrome (PCOS), one of the most common endocrine diseases in women of childbearing age, has been found to be accompanied by changes in the gut microbiota.
Yanyan Yu, Ying Cao, Wenling Huang, Yanxia Liu, Ying Lu, Jiajing Zhao   +5 more
doaj   +1 more source

A multi-methodological protocol to characterize PDO olive oils [PDF]

, 2018
An analytical approach including Panel Test, Isotope Ratio Mass Spectrometry (IRMS) and Nuclear Magnetic Resonance (NMR) spectroscopy was proposed to characterize Italian “Colline Pontine” PDO olive oils (40 samples) of two consecutive crop years.
Camin, Federica, Capitani, Donatella, Centauri, Luigi, Circi, Simone, Di Vecchia, Andrea, D’Achille, Giovanni, Ingallina, Cinzia, Leonardi, Genesio, Mannina, Luisa, Vista, Silvia   +9 more
core   +1 more source