Results 61 to 70 of about 22,609,963 (202)

A Retrospective Study on the Association between Thyroid Autoantibodies with β2-glycoprotein and Cardiolipin Antibodies in Recurrent Miscarriage

Iranian Journal of Allergy, Asthma and Immunology, 2017
Etiologic factors for recurrent miscarriage (RM) include autoimmune diseases, the most frequently antiphospholipid syndrome and thyroiditis. Some women who suffer from RM might also have an altered immune system.
Regina Promberger, Katharina Walch, Rudolf Seemann, Sophie Pils, Johannes Ott   +4 more
doaj  

βeta-2 glycoprotein I is a novel regulator of Apolipoprotein E containing HDL particles in females

Biology of Sex Differences
Background βeta-2 glycoprotein I (β2GPI, Apolipoprotein H) is a plasma glycoprotein best known as a major autoantigen in autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE), both of which confer elevated ...
Ying Wang, Miao Qi, Liming Chen, Maaike Kockx, James Weaver, Leonard Kritharides, Steve Krilis, Bill Giannakopoulos   +7 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Domain V Peptides Inhibit β2-Glycoprotein I-Mediated Mesenteric Ischemia/Reperfusion-Induced Tissue Damage and Inflammation

, 2010
Reperfusion of ischemic tissue induces significant tissue damage in multiple conditions, including myocardial infarctions, stroke, and transplantation. Although not as common, the mortality rate of mesenteric ischemia/reperfusion (IR) remains >70%.
Sherry D. Fleming, Michael R. Pope, John M. Tomich, Urska Bukovnik, Lynn M. Wagner, Sara M. Hoffman, Keith M. Woods, Tiffany Moses   +7 more
core   +1 more source

Beta 2 glycoprotein I Valine247Leucine polymorphism in patients with antiphospholipid syndrome [PDF]

, 2022
Aim: Beta 2 Glycoprotein I (β2-GP I) takes part in the pathogenesis of antiphospholipid syndrome (APS). Valine247Leucine (Val247Leu) gene polymorphism of β2-GP I might affect the binding/production of anti-β2-GP I antibodies. Multiple studies are showing
Nalcaci, Meliha, Tekeoglu, Senem, Bahar Artim-Esen, Murat Inanc, Artim-Esen, Bahar, Inanc, Murat, Senem Tekeoglu, Diz-Kucukkaya, Reyhan, Meliha Nalcaci, Veysel Sabri Hancer, Hancer, Veysel Sabri   +10 more
core   +1 more source

Comparative analysis of prothrombotic activity in patients with myocardial infarction with and without obstructive coronary artery disease

Российский кардиологический журнал, 2021
Aim. To compare parameters of prothrombotic activity in patients with myocardial infarction (MI) with obstructive (MICAD) and non-obstructive coronary artery disease (MINOCA).Material and methods.
D. A. Vorobieva, Yu. G. Lugacheva, N. A. Kapilevich, V. V. Ryabov   +3 more
doaj   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Human β2-glycoprotein I attenuates mouse intestinal ischemia/reperfusion induced injury and inflammation [PDF]

, 2012
Intestinal ischemia-reperfusion (IR)-induced injury results from a complex cascade of inflammatory components. In the mouse model of intestinal IR, the serum protein, β2-glycoprotein I (β2-GPI) binds to the cell surface early in the cascade. The bound β2-
Yasuaki Hiromasa, Sherry D. Fleming, Pope, Michael R., Sushanth Gudlur, Tomasi, Maurizio, Tomich, John M., Gudlur, Sushanth, Michael R. Pope, John M. Tomich, Hiromasa, Yasuaki, Maurizio Tomasi, Fleming, Sherry D.   +11 more
core   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

‐glycoprotein I

, 1992
Complexes formed by the interaction of negatively charged phospholipids and β2-glycoprotein I(β2-I) are the target of autoantibodies in systemic lupus erythematosus.
Kertesz, Zsuzsa, Campbell, Iain D., Zsuzsa Kertesz, Robert B. Sim, Alexander Steinkasser, David G. Norman, Iain D. Campbell, Norman, David G., Sim, Robert B., Barlow, Paul N., Willis, Anthony C., Paul N. Barlow, Anthony C. Willis, Steinkasser, Alexander   +13 more
core   +1 more source