Results 71 to 80 of about 22,609,963 (202)

Antiphospholipid Antibody Profile in HIV/AIDS Patients

Jurnal Penyakit Dalam Indonesia, 2017
Introduction. Through the process of molecular mimicry, human immunodeficiency virus (HIV) infection can increase the concentration of antiphospholipid antibody (APA) which has possible association with thrombosis.
Inolyn Pandjaitan, Nanang Sukmana, Shufrie Effendy   +2 more
doaj   +1 more source

Reassessing the role of antiphospholipid antibodies in placental‐mediated adverse pregnancy outcomes in systemic lupus erythematosus: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang, Yanling Chang, Ning Zhang, Wen Di, Jiayue Wu   +4 more
wiley   +1 more source

Conformational Change of β2-glycoprotein I : Evaluation of Difference in Binding Capacity of Autoantibodies to Open and Closed Forms of β2-glycoprotein I

, 2013
Antiphospolipidsyndrome (APS) is one of the most common autoimmune diseases characterized bythrombosis, fetal loss and presence of antiphospholipid antibodies.
Wagner, Ylva
core   +3 more sources

Is it necessary to perform connective tissue disorders laboratory tests when a patient experiences the first demyelinating attack?

Journal of Research in Medical Sciences, 2013
Background: It may be difficult to differentiate between the first demyelinating attack and the neurological manifestations of connective tissue diseases.
Masoud Etemadifar, Alimohammad Fatemi, Hourossadat Hashemijazi, Amir Kazemizadeh   +3 more
doaj  

Antiphospholipid Antibodies Bind ATP: A putative Mechanism for the Pathogenesis of Neuronal Dysfunction

Clinical and Developmental Immunology, 2005
Antiphospholipid antibodies (aPL) generated in experimental animals cross-react with ATP. We therefore examined the possibility that aPL IgG from human subjects bind to ATP by affinity column and an enzyme linked ...
J. Chapman, L. Soloveichick, S. Shavit, Y. Shoenfeld, A. D. Korczyn   +4 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

A mechanism of development of arterial thrombosis : β2-glycoprotein I-specific ligand and autoantibody [PDF]

, 2002
β2-Glycoprotein I (β2-GPI) is a major antigen for anticardiolipin antibodies (aCL) appeared in patients with antiphospholipid syndrome (APS). We recently reported that β2-GPI specifically binds to oxidized low-density lipoprotein (oxLDL) and that on of ...
Liu, Qingping
core  

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Factors Associated With Bilateral Involvement in Non‐Infectious Labyrinthitis: A Case–Control Study

The Laryngoscope, EarlyView.
Non‐infectious labyrinthitis may progress from unilateral to bilateral inner‐ear involvement, resulting in greater functional impairment. In this retrospective case–control study of 50 patients, younger age, female sex, and the presence of systemic disease were associated with bilateral involvement. These exploratory findings may help identify patients
Douglas Henderson, Blanca Amador Borrero, Aurélien Cadix, Karine Champion, Damien Sene, Philippe Herman, Charlotte Hautefort, Alain Londero, Michael Eliezer, Cassandre Djian   +9 more
wiley   +1 more source

Involvement of β2-glycoprotein I and anticardiolipin antibodies in oxidatively modified low-density lipoprotein uptake by macrophages

, 1997
SUMMARY Anticardiolipin antibodies (aCL) in the sera of patients with antiphospholipid syndrome (APS) recognize an altered structure of β2-glycoprotein I (β2-GPI) interacting with solid-phase negatively charged phospholipids.
S NISHI, E MATSUURA, Z MAKITA, Y HASUNUMA, T KATAHIRA, T KOIKE   +5 more
core   +1 more source