Results 91 to 100 of about 22,609,963 (202)

Equation and performance characteristics of multiple linear fixed-effect and mixed-effect models using data from non-infected controls and SARS-CoV-2 infected individuals.

, 2021
The best model is shown in bold letters (AIC, Akaike information criterion; β2, β2-glycoprotein I; DPO, day post onset; PC, principal component). (DOCX)
Martin F. Sprinzl (4339777), Vishalini Emmenegger (11790839), Adriano Aguzzi (49294), Marc Emmenegger (11614492), Laura Rose (749727), Karl J. Lackner (7404842), Clemens J. Sommer (11790845), Dirk Roggenbuck (407723), Sreedhar Saseendran Kumar (11790836), Peter Schierack (355803), Tomas Malinauskas (10040777), Thomas Buettner (11790842), Katrin B. M. Frauenknecht (11790848)   +12 more
core   +1 more source

Construction optimization and functional applications of fluorescent nanodiamonds

Responsive Materials, EarlyView.
This review summarizes synthesis, surface modification and optical properties of fluorescent nanodiamonds. Their advances in quantum sensing, single‐photon emission and biomedicine are discussed, and existing challenges and future directions are presented.
Yunpeng Yang, Sen Zhang, Chao Chen, Wensi Yang, Zuanquan Chen, Rui Fan, Linlin Liu, Benjian Liu, Kang Liu, Zhibo Zhang, Bing Dai, Jiaqi Zhu   +11 more
wiley   +1 more source

Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation

Integrative Zoology, EarlyView.
Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv, Wanfei Deng, Fei Deng, Shixia Xu, Wenhua Ren   +4 more
wiley   +1 more source

Antibodies to age-β2 glycoprotein I in patients with antiphospholipid antibody syndrome.

, 2016
Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease clinically characterized by arterial and/or venous thromboses, recurrent abortions or fetal loss and serologically by the presence of "antiphospholipid antibodies" (aPL).
B Buttari, Facchiano, F, R Misasi, A Capozzi, Buttari, B, CAPOZZI, ANTONELLA, CONTI, FABRIZIO, S Truglia, F Facchiano, F Conti, R Riganò, G Valesini, Riganò, R., RECALCHI, SERENA, C Alessandri, Profumo, E, ALESSANDRI, cristiano, S Recalchi, MISASI, Roberta, SORICE, Maurizio, VALESINI, Guido, M Sorice, E Profumo, TRUGLIA, SIMONA   +23 more
core   +1 more source

Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome

Frontiers in Immunology
IntroductionUnfolded Von Willebrand Factor (VWF) is increased in thrombotic pathologies such as myocardial infarction. Unfolded VWF mediates the binding of platelets without the need for collagen.
Romy de Laat-Kremers, Shengshi Huang, Shengshi Huang, Hugo ten Cate, Hugo ten Cate, Marisa Ninivaggi, Bas de Laat, Bas de Laat, Katrien Devreese, Katrien Devreese   +9 more
doaj   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

The morphology of porcine oocytes is associated with zona pellucida glycoprotein 3 and integrin beta 2 protein levels--

Veterinární Medicína, 2010
The morphology and quality of oocytes is set during oo- and folliculo-genesis, and is completed during final maturation. Early embryonic development is associated with the morphology of the cumulus-oocyte-complex (COC).
P. Antosik, B. Kempisty, M. Jackowska, D. Bukowska, M. Lianeri, K.P. Brussow, M. Wozna, J.M. Jaskowski   +7 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Serum autoantibody panel as a novel predictor for preeclampsia: a nested case-control study

BMC Pregnancy and Childbirth
Background Preeclampsia is a severe pregnancy-related complication that poses a major threat to the health of both mothers and fetuses. Early identification of high-risk pregnant women remains one of the key clinical challenges.
Kai Cheng, Qian Gao, Yuping Duan, Hui Zhang, Leiming Cai, Qian Li   +5 more
doaj   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source