Results 41 to 50 of about 24,699 (164)

Urine β2 Microglobulin and other Biochemical Indices in β Thalassemia Major [PDF]

Acta Medica Iranica, 2009
To find if some indices have predictive value for renal complications. We conducted a cross sectional and included 80 patients with the age ranged 5-17 years, all with the proven diagnosis of β-thalassemia major.
Yazdan Ghandi, Abtin Heidarzadeh, Shohreh Maleknejad, Afshin Safaei asl   +3 more
doaj   +2 more sources

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Serum ß2-Microglobulin lin Patients with Monoclonal Gammopathies

The International Journal of Biological Markers, 1987
Beta-2-microglobulin concentrations were determined in serum samples from 45 patients with benign and malignant monoclonal gammopathies. In the group of patients suffering from multiple myeloma or Waldenström macroglobulinemia the mean β2-microglobulin ...
Samuele Di Giovanni, Gaetano Valentini, Emma Ravazzolo, Paolo Carducci, Paolo Giallonardo, Camillo Maschio   +5 more
doaj   +1 more source

Serum Beta-2 Microglobulin as a Prognostic Marker of Diabetic Nephropathy in Egyptian Patients [PDF]

Al-Azhar International Medical Journal, 2000
Background: Globally, diabetic nephropathy (DN) is the most prevalent microvascular complication and primary cause of chronic kidney disease (CKD). Aim: To assess the serum beta-2 microglobulin level as a predictive indicator of DN. Patients and methods:
Mohamed AL-alfy, Ayman Salem, Mohamed Shaheen, Mohamed Abdallah   +3 more
doaj   +1 more source

Continuous Purification of mRNA Produced by In Vitro Transcription Using High Performance Countercurrent Membrane Purification

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang, Amin Javidanbardan, Ali Behboudi, Andrew L. Zydney   +3 more
wiley   +1 more source

Urinary β2 Microglobulin in Workers Exposed to Arc Welding Fumes [PDF]

Acta Medica Iranica, 2011
Welding is a process in which two or more metals are attached by the use of heat and, in some cases, pressure. Direct exposure and inhalation of welding fumes causes acute and chronic side effects in humans.
Khosro Sadeghniiat-Haghighi, Seyed Akbar Sharifian, Maria Mazaheri, Saeid Eftekhari, Omid Aminian   +4 more
doaj   +2 more sources

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Correlation of Beta-2 Microglobulin with serum creatinine and creatinine clearance in patients with different levels of renal function

Gomal Journal of Medical Sciences, 2012
Background: Chronic kidney disease is a major health problem in Pakistan. Serum creatinine is the most common test used to assess renal function. This study was aimed to evaluate the levels of β2 Microglobulin and creatinine in individuals with different
Shahjahan, Riffat Yasmin, Muhammad Amin Jan Mahsud, Mahnoor Khan, Jawaid Subzwari, Javaid Hussain   +5 more
doaj