Results 81 to 90 of about 24,699 (164)
Unusual Lesions in a Long‐Term Dialysis Patient
Oral Diseases, EarlyView.
Domenico De Falco +2 more
wiley +1 more source
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune, demyelinating disorder of the central nervous system. Clinical manifestations include optic neuritis, longitudinally extensive transverse myelitis (LETM) involving three or more vertebral segments, and, in most cases, seropositivity for anti‐aquaporin‐4 antibodies (AQP4‐IgG).
Nikolina Pravdic +7 more
wiley +1 more source
The Challenge of Determining the Etiology of Encephalopathy in an Elderly Patient
ABSTRACT Encephalopathy is a heterogeneous clinical syndrome with numerous neurological and systemic etiologies. We report the case of a 67‐year‐old man, a chronic ethanol consumer, admitted with a one‐week history of confusional syndrome. Initial laboratory tests revealed severe hypercalcemia, acute kidney injury, mild anemia, and hyperproteinemia ...
Vlad Alexandru Ionescu +9 more
wiley +1 more source
Treatment of Restless Legs Syndrome in Dialysis Patients
Seminars in Dialysis, EarlyView.
Kenji Sakurai +4 more
wiley +1 more source
Roles of Microglia in Cerebral Small Vessel Disease
Chronic cerebral hypoperfusion triggers microglial activation in cerebral small vessel disease (CSVD). Activated microglia drive neuroinflammation, oxidative stress, and blood–brain barrier disruption, leading to white matter hyperintensities, enlarged perivascular spaces, and other neuroimaging features.
Chenyang Jin +7 more
wiley +1 more source
Immunophenotypic characteristics of plasma cells in POEMS syndrome
Abstract To analyze the immunophenotypic characteristics of plasma cells in patients with polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes (POEMS) syndrome. This retrospective study included patients with POEMS syndrome hospitalized in the Department of Hematology, Huashan Hospital, from September 2017 to August 2025 ...
Zhenhua Wang +6 more
wiley +1 more source
Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu +5 more
wiley +1 more source
Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers
This schematic illustrates the hierarchical and interconnected nature of the primary molecular hallmarks of aging. The progression of aging is driven by a convergence of intrinsic molecular insults. Within the nucleus, genomic instability and telomere attrition trigger persistent DDR, accompanied by extensive epigenetic alterations.
Guowei Cai +10 more
wiley +1 more source
Background Previous studies highlighted the utility of individual urinary biomarkers in the prediction of interstitial fibrosis in IgA Nephropathy patients.
Jorge González Rodríguez +10 more
doaj +1 more source
ABSTRACT Dynamic changes in myeloid‐derived suppressor cells (MDSCs) during multiple myeloma (MM) treatment remain poorly understood. In this longitudinal observational study, circulating monocytic (M‐MDSCs) and polymorphonuclear MDSCs (PMN‐MDSCs) were measured by flow cytometry in 99 newly diagnosed MM patients at diagnosis, post‐induction, and Day ...
Qi Yan +11 more
wiley +1 more source

