Results 111 to 120 of about 2,357,602 (292)
Evidence of microbial activity from a shallow water whale fall (Voghera, northern Italy) [PDF]
The fossil bones, associated carbonate cements and enclosing concretion of a Miocene mysticete from inner shelf deposits (Monte Vallassa Formation, northern Italy) were analyzed for evidence of microbial activity. Optical and scanning electron microscopy,
Cavalazzi, B +5 more
core +4 more sources
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Nonlinear Stability of ρ-Functional Equations in Latticetic Random Banach Lattice Spaces
In this paper, we prove the generalized nonlinear stability of the first and second of the following ρ -functional equations, G ( | a | Δ A * | b | ) Δ B * G ( | a | Δ A * * | b | ) − G ( | a | ) Δ B * * G ( | b | ) = ρ (
Mohammad Maleki V. +2 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Information Technology, Organisational Change and Productivity Growth: Evidence from UK Firms [PDF]
We examine the relationships between productivity growth, IT investment and organisational change (Δ O) using UK firm panel data. Consistent with the small number of other micro studies we find (a) IT appears to have high returns in a growth accounting ...
Chiara Criscuolo +2 more
core
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
LP-212 SLE overlap with psoriatic arthritis successfully treated with secukinumab
Athina Theodoridou
doaj +1 more source

