Results 51 to 60 of about 5,905 (229)

Appendix A. The mechanistic framework for using cellulose δ18O and δD to predict leaf water δ18O and δD and thereby calculate deuterium deviations from the global meteoric water line (Δd).

open access: yes, 2016
The mechanistic framework for using cellulose δ18O and δD to predict leaf water δ18O and δD and thereby calculate deuterium deviations from the global meteoric water line (Δd)
Slawomira Pawelczyk (2910035)   +9 more
core   +1 more source

Volcanic Glass as a Proxy for Paleotopography Suggests New Features in Late-Miocene Oregon

open access: yesAtmosphere
Volcanic glass has been used extensively as a paleoaltimeter. Deuterium (2H) concentrations in glass have been found to be stable over geologic timescales, making δ2H (also known as δD) a reliable proxy for ancient water chemistry.
Julian Cohen, John Bershaw, Richard Hugo
doaj   +1 more source

HDO/H2O ratio retrievals from GOSAT [PDF]

open access: yesAtmospheric Measurement Techniques, 2013
We report a new shortwave infrared (SWIR) retrieval of the column-averaged HDO/H2O ratio from the Japanese Greenhouse Gases Observing Satellite (GOSAT). From synthetic simulation studies, we have estimated that the inferred δD values will typically have ...
H. Boesch   +8 more
doaj   +1 more source

Continuous-Flow Analysis of δ17O, δ18O, and δD of H2O on an Ice Core from the South Pole

open access: yesFrontiers in Earth Science, 2021
The δD and δ18O values of water are key measurements in polar ice-core research, owing to their strong and well-understood relationship with local temperature.
Eric J. Steig   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The δ18O and δD isoscapes of recent groundwater in Poland [PDF]

open access: yes, 2019
Considering the country’s development and quality of life, recognition of the water cycle mechanism is of great importance. A significant contribution to this comes from the isotopic composition of particular elements of the water cycle.
Leśniak, Paweł M., Wilamowski, Andrzej
core   +2 more sources

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Abrupt Geographic Shift in Hydrogen Isotope Ratios of Meteoric Water Across the Western Andes, Peru

open access: yesGeophysical Research Letters
Quantitative isotopic paleoaltimetry has been applied in regions where Rayleigh distillation controls isotopic lapse rates. Air mass mixing and moisture recycling are viewed as complicating factors.
Emily J. White   +2 more
doaj   +1 more source

Correlation of cilofungin in vivo efficacy with its activity againstAspergillus fumigatus(1,3)-β-d-glucan synthase [PDF]

open access: yesFEMS Microbiology Letters, 1993
(1,3)-beta-D-Glucan synthase is a cell wall synthesis enzyme that is the target of cilofungin, an antifungal agent of the lipopeptide class. Cilofungin's glucan synthase inhibitory activity, MIC, and effective dose 50% in a systemic infection mouse model tend to correlate for Candida albicans. This correlation is not seen in Aspergillus fumigatus. MICs
D, Beaulieu   +3 more
openaire   +2 more sources

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

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