Results 51 to 60 of about 5,905 (229)
The mechanistic framework for using cellulose δ18O and δD to predict leaf water δ18O and δD and thereby calculate deuterium deviations from the global meteoric water line (Δd)
Slawomira Pawelczyk (2910035) +9 more
core +1 more source
Volcanic Glass as a Proxy for Paleotopography Suggests New Features in Late-Miocene Oregon
Volcanic glass has been used extensively as a paleoaltimeter. Deuterium (2H) concentrations in glass have been found to be stable over geologic timescales, making δ2H (also known as δD) a reliable proxy for ancient water chemistry.
Julian Cohen, John Bershaw, Richard Hugo
doaj +1 more source
HDO/H2O ratio retrievals from GOSAT [PDF]
We report a new shortwave infrared (SWIR) retrieval of the column-averaged HDO/H2O ratio from the Japanese Greenhouse Gases Observing Satellite (GOSAT). From synthetic simulation studies, we have estimated that the inferred δD values will typically have ...
H. Boesch +8 more
doaj +1 more source
Continuous-Flow Analysis of δ17O, δ18O, and δD of H2O on an Ice Core from the South Pole
The δD and δ18O values of water are key measurements in polar ice-core research, owing to their strong and well-understood relationship with local temperature.
Eric J. Steig +7 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The δ18O and δD isoscapes of recent groundwater in Poland [PDF]
Considering the country’s development and quality of life, recognition of the water cycle mechanism is of great importance. A significant contribution to this comes from the isotopic composition of particular elements of the water cycle.
Leśniak, Paweł M., Wilamowski, Andrzej
core +2 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Abrupt Geographic Shift in Hydrogen Isotope Ratios of Meteoric Water Across the Western Andes, Peru
Quantitative isotopic paleoaltimetry has been applied in regions where Rayleigh distillation controls isotopic lapse rates. Air mass mixing and moisture recycling are viewed as complicating factors.
Emily J. White +2 more
doaj +1 more source
Correlation of cilofungin in vivo efficacy with its activity againstAspergillus fumigatus(1,3)-β-d-glucan synthase [PDF]
(1,3)-beta-D-Glucan synthase is a cell wall synthesis enzyme that is the target of cilofungin, an antifungal agent of the lipopeptide class. Cilofungin's glucan synthase inhibitory activity, MIC, and effective dose 50% in a systemic infection mouse model tend to correlate for Candida albicans. This correlation is not seen in Aspergillus fumigatus. MICs
D, Beaulieu +3 more
openaire +2 more sources
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source

