Results 31 to 40 of about 1,096 (127)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Nano-Micro Encapsulation of Drugs [PDF]

, 2022
This Special Issue covers different aspects of the nano/microencapsulation of drugs, including papers describing the design, preparation, and characterization of nano- and micro-carrier-based drug delivery systems and the latest developments in key ...

core   +1 more source

Cyclodextrin‐Amino Acid Conjugates: Synthesis and Pharmaceutical Applications

ChemistryEurope, Volume 4, Issue 4, April 2026.
Cyclodextrins (CDs) can be combined with amino acids via host‐guest complexation or by covalent conjugation through various synthetic routes. The chemical modifications introduce structural versatility, multifunctionality, and biocompatibility, which are essential characteristics for designing effective, next‐generation pharmaceutical formulations ...
Andrea Cesari, Nicola Lomuscio, Fabio Bellina   +2 more
wiley   +1 more source

An Allosteric Inhibitor of KRas Identified Using a Barcoded Rapid Assay Microchip Platform [PDF]

, 1993
Protein catalyzed capture agents (PCCs) are synthetic antibody surrogates that can target a wide variety of biologically relevant proteins. As a step toward developing a high-throughput PCC pipeline, we report on the preparation of a barcoded rapid assay
McCarthy, Amy Michelle, Kim, Jungwoo, Museth, A. Katrine, Henning, Ryan K., Heath, John E., Winson, Emma, Oh, Joseph J., Liang, Jingxin, Hong, Sunga, Heath, James R.   +9 more
core  

Synthesis and Self-Assembly of Well-Defined Block Copolypeptides via Controlled NCA Polymerization [PDF]

, 2013
This article summarizes advances in the synthesis of well-defined polypeptides and block copolypeptides. Traditional methods used to polymerize α-amino acid-N-carboxyanhydrides (NCAs) are described, and limitations in the utility of these systems for the
A Aggeli, A Aggeli, A Sulistio, AA Goodwin, AH Zisch, AJ Rhodes, AP Nowak, AP Nowak, AR Rodriguez, B Song, BJ Sparks, C Branden, C Chen, C Holt, C-Y Yang, D Thunig, DE Discher, DL Pickel, E Bellomo, E Katchalski, EP Holowka, EP Holowka, EP Holowka, F Cardinaux, F Uralil, FPJT Rutjes, G Kwon, GD Fasman, GJM Habraken, GJM Habraken, GS Kwon, H Cao, H Fischer, H Iatrou, H Lu, H Lu, H Lu, H Sekiguchi, H Sekiguchi, HE Auer, HR Kricheldorf, J Cheng, J Gaspard, J Huang, J Hwang, J Rodriguez-Hernandez, J Sun, J-F Lutz, J-K Lai, JA Hanson, JA Hanson, JA Hanson, JC Howard, JH Waite, JN Cha, JP Collman, JR Kramer, JR Kramer, JR Kramer, JR Kramer, JW Nah, KE Schaefer, KR Brzezinska, KY Lee, L Pakstis, L Richert, L Xia, L-TT Nguyen, LF Zhang, M Meyer, M Mondeshki, M Sela, M Wilhelm, M Yu, MI Gibson, MP Lutolf, NA Peppas, O Webster, O Webster, P Alexandridis, P Witte, R Graf, RB Woodward, RE Epand, RT Ingwall, S Kubota, S Zhang, SA Curtin, SE Ostroy, SW Seidel, T Aliferis, T Kidchob, T Tanaka, TJ Deming, TJ Deming, TJ Deming, TJ Deming, TJ Deming, TJ Deming, TJ Deming, TJ Deming, U-J Choe, VP Torchilin, VZ Sun, VZ Sun, W Vayaboury, W Zhuang, X Fu, Y Liu, Y-L Peng, Y-Y Hu, YI Jeong, Z Li   +112 more
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Engineered Cellulose: A Multifunctional Platform for Next‐Generation Sustainable Environmental Technologies

EcoMat, Volume 8, Issue 4, April 2026.
Engineered cellulose—enabled by functionalization, hybridization, and nano‐engineering—emerges as a versatile platform driving next‐generation solutions in water purification, CO2 capture, air filtration, soil remediation, energy storage, and sustainable packaging. ABSTRACT Engineered cellulose is redefining the frontier of sustainable materials in the
Amir Hossein Behroozi, Tizazu H. Mekonnen   +1 more
wiley   +1 more source

Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats

Advanced Functional Materials, Volume 36, Issue 22, 16 March 2026.
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr, Saptarshi Biswas, Jacob Aragon, Asaf Dana, Jasmine Sureka, Vaaridhi Ramanuja, Jeevika Thazhaiselvam, Sarah E. Miller, Taylor H. Ware, Akhilesh K. Gaharwar   +9 more
wiley   +1 more source

Stimuli‐responsive hydrogels: An intelligent tool for wound management

Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.
For chronic and complex wounds, this review focuses on intelligent hydrogels capable of responding to wound microenvironmental cues (e.g., pH, enzymes) or external stimuli (e.g., light, electricity). These advanced materials enable the dynamic regulation of drug release and real‐time monitoring of healing progression, thereby offering innovative ...
Debin Zheng, Meiqi Zhu, Xi Liu, Cuiping Zhang, Di Wu, Tianyu Xie, Chen Li, Pei Zhao, Wenting Chen, Xiaobing Fu, Xiaoxue Li   +10 more
wiley   +1 more source

Thermoresponsive Polysarcosine-Based Nanoparticles [PDF]

, 2019
Polysarcosine holds great promise as an alternative to poly(ethylene glycol) for use within both biomedical and non-biomedical applications owing to its hydrophilicity and non-cytoxicity, amongst other features.
Birke, Birke, Chan, Chapman, Cui, Deng, Deng, Doriti, Du, Fetsch, Fetsch, Gangloff, Gao, Holm, Hu, Hu, Huesmann, Khuphe, Khuphe, Khuphe, Kim, Klinker, Lau, Tao, Varlas, Viricel, Warren, Warren, Weber, Yu   +29 more
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Effect of Slightly Acidic Electrolyzed Water Combined with ε-Polylysine Hydrochloride on Storage Quality of Micropterus salmoides Fillets

Shipin gongye ke-ji
To investigate the effects of combined treatment with slightly acidic electrolyzed water (SAEW) and ε-polylysine hydrochloride (ε-PLH) on the refrigerated quality of largemouth bass (Micropterus salmoides) fillets, this study selected bass with a weight ...
Zhili JIANG, Chenglong WU, Lingling SHEN, Zhen WU, Yangguang WANG, Shengmin LU   +5 more
doaj   +1 more source