Results 41 to 50 of about 125,899 (235)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

λ-Orthogonale Photochemie: Lichtinduzierte pericyclische Reaktionen an Makromolekülen

, 2015
Eine photochemische Strategie nutzt λ-orthogonale Reaktionen zum Aufbau makromolekularer Architekturen und zum wellenlängenabhängigen Einbau chemischer Funktionalitäten in ein einzelnes Molekül.
Pauloehrl, Thomas, Linkert, Katharina, Börner, Hans G., Blinco, James P., Barner-Kowollik, Christopher, Hiltebrandt, Kai   +5 more
core   +1 more source

Measurement of branching fractions of $Λ_c^ + → η Λ π ^+, η Σ^0 π^ + , Λ ( 1670 ) π^+$ , and $η Σ ( 1385 )^ +$

, 2021
We report branching fraction measurements of four decay modes of the Λ+c baryon, each of which includes an η meson and a Λ baryon in the final state, and all of which are measured relative to the Λ+c→pK−π+ decay mode. The results are based on a 980  fb−1
Shebalin, V., Vorobyev, V., Hsu, C.-L., Hayashii, H., Gaur, V., Hayasaka, K., Onuki, Y., Yang, S. B., Kinoshita, K., Watanabe, M., Cunliffe, S., Stottler, Z. S., MacQueen, C., Sumiyoshi, T., Cervenkov, D., Cinabro, D., Chilikin, K., Di Capua, F., Hernandez Villanueva, M., Kim, Y. J., Uchida, M., Itoh, R., Li, C. H., Yuan, C. Z., Sangal, A., Stanič, S., Garmash, A., Ogawa, K., Bozek, A., Beleño, C., Paul, S., Oskin, P., Schwanda, C., Popov, V., Patra, S., Jang, E.-J., Kumara, K., Nishida, S., De Nardo, G., Liptak, Z., Jacobs, W. W., Podobnik, T., Bilka, T., Ahn, J. K., Križan, P., Asner, D. M., Schueler, J., Moon, T. J., Vossen, A., Lee, S. C., Tamponi, U., Kim, B. H., Joo, K. K., Pakhlova, G., Senyo, K., Chen, A., Campajola, M., Prencipe, E., Cho, K., Mizuk, R., Bennett, J., Choi, S.-K., Vahsen, S. E., Pedlar, T. K., Biswal, J., Sutcliffe, W., Cheon, B. G., Wang, P., Watanuki, S., Hadjivasiliou, C., Park, S.-H., Pardi, S., Ishikawa, A., Sandilya, S., Uno, S., Kuzmin, A., Li, Y. B., Libby, J., Schwartz, A. J., Nayak, M., Yusa, Y., Bessner, M., Mussa, R., Uglov, T., Wang, C. H., Kuhr, T., Iwasaki, M., Piilonen, L. E., Varner, G., Li Gioi, L., Vinokurova, A., Zhilich, V., Van Tonder, R., Browder, T. E., Giri, A., Cao, L., Jin, Y., Nakao, M., Kim, Y.-K., Kato, Y., Kim, K. T., Starič, M., Chang, P., Kiesling, C., Shapkin, M., Zhulanov., V., Kodyš, P., Kim, S. H., Usov, Y., Chekelian, V., Doležal, Z., Kroeger, R., Nisar, N. K., Sokolov, A., Seidl, R., Mori, T., Nakano, T., Ferber, T., Miyabayashi, K., Prim, M. T., Zhang, Z. P., Garg, R., Xu, X., Pakhlov, P., Epifanov, D., Ogawa, S., Inami, K., Karyan, G., Ono, H., Shwartz, B., Kang, K. H., Hartbrich, O., Mohanty, G. B., Sahoo, D., Fulsom, B. G., Aushev, T., Bonvicini, G., Wang, M.-Z., Schnell, G., Savinov, V., Krokovny, P., Eidelman, S., Pestotnik, R., Bhuyan, B., Lieret, K., Dong, T. V., Kotchetkov, D., Rostomyan, A., Luo, T., Kichimi, H., Kwon, Y.-J., Niiyama, M., Li, L. K., Kim, S. K., Sakai, Y., Ayad, R., Behera, P., Wang, E., Tenchini, F., Kim, D. Y., Russo, G., Goldenzweig, P., Santelj, L., Joo, C. W., Korpar, S., Natochii, A., Olsen, S. L., Choi, Y., Jia, S., Choudhury, S., Zhukova, V., Liventsev, D., Yin, J. H., Sevior, M. E., Rout, N., Yan, W., Solovieva, E., Bahinipati, S., Yelton, J., Matvienko, D., Yabsley, B. D., Adachi, I., Shiu, J.-G., Wiechczynski, J., Lee, J. Y., Kulasiri, R., Ye, Hua, Aihara, H., Takizawa, M., Belle Collaboration, Wehle, S., Hedges, M. T., Babu, V., Kim, K.-H., Chang, M.-C., Golob, B., Al Said, S., Sumihama, M., Merola, M., Tanida, K., Seino, Y., Bračko, M., Masuda, M., Matsuda, T.   +203 more
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Noncollinear Equilibrium Points in CRTBP with Yukawa-Like Corrections to Newtonian Potential under an Oblate Primary Model

Advances in Astronomy, 2023
This study is about the effects of Yukawa-like corrections to Newtonian potential on the existence and stability of noncollinear equilibrium points in a circular restricted three-body problem when bigger primary is an oblate spheroid. It is observed that
M. Javed Idrisi, Sunusi Haruna, Teklehaimanot Eshetie   +2 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Testing lepton flavour universality in semileptonic Λ b  → Λ c * decays

Journal of High Energy Physics, 2018
Lepton Flavour Universality tests with semileptonic Λ b  → Λ c * decays are important to corroborate the present anomalies in the similar ratios RD∗ $$ {R_D}_{{}^{\left(\ast \right)}} $$, and can provide complementary constraints on possible origins of ...
Philipp Böer, Marzia Bordone, Elena Graverini, Patrick Owen, Marcello Rotondo, Danny van Dyk   +5 more
doaj   +1 more source

Asymmetric λ–deformed cosets

Nuclear Physics B, 2020
We study the integrable asymmetric λ-deformations of the SO(n+1)/SO(n) coset models, following the prescription proposed in [1]. We construct all corresponding deformed geometries in an inductive way. Remarkably we find a Z2 transformation which maps the
Jia Tian, Jue Hou, Bin Chen
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source