Results 51 to 60 of about 1,148 (144)

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

open access: yesExploration, Volume 6, Issue 2, April 2026.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang   +7 more
wiley   +1 more source

Flexible, Integrated‐Porous Microneedle Sensor for Biofluid Sampling and On‐Site Biomarker Detection

open access: yesAdvanced Materials Technologies, Volume 11, Issue 5, 6 March 2026.
A paper‐integrated porous PGA microneedle array patch capable of both high strength and absorption capacity is proposed. With an image‐processing system, an optimized colorimetric sensor achieves a low limit of detection of 0.09 mm in cholesterol.
Haitao Deng   +3 more
wiley   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

open access: yesAdvanced Sensor Research, Volume 5, Issue 2, February 2026.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Paper-based diagnostics for COVID-19 developed by CSIR-IGIB [PDF]

open access: yes, 2020
28-29On 3rd April, CSIR achieved a breakthrough in its ongoing war against devastating coronavirus as CSIR-IGIB developed a low-cost diagnostic paper-based kit that can accurately test COVID-19 ...
Mahesh, G
core  

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Aptamer and DNAzyme Based Colorimetric Biosensors for Pathogen Detection

open access: yesAngewandte Chemie, Volume 137, Issue 4, January 21, 2025.
Pathogen detection is crucial for preventing and managing health risks. This review consolidates the selection of functional nucleic acids (FNAs) for pathogen detection and the development of cost‐effective, simple diagnostic applications. It focuses on integrating FNAs with gold nanoparticles, polydiacetylenes, protein enzymes, G‐quadruplexes, and ...
Rudi Liu   +3 more
wiley   +2 more sources

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Progress and Prospect of Integrated Microfluidic, Electrochemical, Liquid Crystal Technologies, and Machine Learning for Wearable Biosensors

open access: yesEngineering Reports, Volume 8, Issue 1, January 2026.
This review highlights advances in integrating microfluidic, electrochemical, and liquid crystal technologies for wearable biosensors. These hybrid systems enable non‐invasive, real‐time monitoring of biofluids and, when coupled with machine learning, offer new opportunities for personalized healthcare diagnostics.
Milad Esfandiar   +2 more
wiley   +1 more source

Reduction with zinc - Impact on the determination of nitrite and nitrate ions using microfluidic paper-based analytical devices [PDF]

open access: yes
We used a microfluidic paper-based analytical device (mu PAD) to investigate the influence that zinc reduction exerts on the determination of nitrite and nitrate ions in natural water samples.
Aoki, Kaoru   +6 more
core   +1 more source

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