Results 51 to 60 of about 825 (144)

A portable system for economical nucleic acid amplification testing

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Introduction: Regular and rapid large-scale screening for pathogens is crucial for controlling pandemics like Coronavirus Disease 2019 (COVID-19). In this study, we present the development of a digital point-of-care testing (POCT) system utilizing ...
Hui Dong   +10 more
doaj   +1 more source

CRISPR‐Enabled Point‐of‐Care Diagnostics for Early Cancer Detection

open access: yesAggregate, Volume 7, Issue 7, July 2026.
This review summarizes recent advances in CRISPR‐enabled point‐of‐care diagnostics for early cancer detection, covering Cas‐based recognition mechanisms, portable engineering platforms, and biomarker applications. It further highlights current challenges and future opportunities for translating sensitive, affordable, and accessible CRISPR diagnostics ...
Yuwei Pan   +3 more
wiley   +1 more source

Three-Dimensional Paper-Based Microfluidic Analytical Devices Integrated with a Plasma Separation Membrane for the Detection of Biomarkers in Whole Blood [PDF]

open access: yes, 2019
Paper-based microfluidic analytical devices (μPADs) have recently attracted attention as a point-of-care test kit because of their low cost and nonrequirement for external forces.
Soo-Kyung Kim (1632286)   +5 more
core   +1 more source

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

Wearable biofluids colorimetric biosensors

open access: yesFlexMat, Volume 3, Issue 2, Page 299-326, June 2026.
Wearable and flexible colorimetric sensors enable real‐time, non‐invasive detection through visible color changes. Advances in materials and device engineering have driven their development; however, challenges remain in sensitivity, selectivity, and scalable manufacturing.
Zhaoyuan Lyu   +8 more
wiley   +1 more source

Microengineering the Liver: Strategies for Constructing Functional Liver‐on‐a‐Chip Devices

open access: yesExploration, Volume 6, Issue 2, April 2026.
This review summarizes recent advances in liver‐on‐a‐chip (LOC) technologies, including fabrication strategies and functional integration approaches, and discusses their promising applications in drug screening and related biomedical fields. ABSTRACT Reliable in vitro liver models are indispensable for researching liver diseases and developing ...
Jie Wang   +7 more
wiley   +1 more source

Flexible, Integrated‐Porous Microneedle Sensor for Biofluid Sampling and On‐Site Biomarker Detection

open access: yesAdvanced Materials Technologies, Volume 11, Issue 5, 6 March 2026.
A paper‐integrated porous PGA microneedle array patch capable of both high strength and absorption capacity is proposed. With an image‐processing system, an optimized colorimetric sensor achieves a low limit of detection of 0.09 mm in cholesterol.
Haitao Deng   +3 more
wiley   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

open access: yesAdvanced Sensor Research, Volume 5, Issue 2, February 2026.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Automated Immunoassay Performed on a 3D Microfluidic Paper-Based Device for Malaria Detection by Ambient Mass Spectrometry [PDF]

open access: yes, 2022
Microfluidic paper-based analytical devices (μPADs) are emerging as a prominent platform for disease detection, specifically in developing countries.
Sierra Jackson   +5 more
core   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy