Results 91 to 100 of about 109,939 (248)

A New Approach to the Study of Multi-Pass Welds–Microstructure and Properties of Welded 20-mm-Thick Superduplex Stainless Steel

Applied Sciences, 2019
Type 2507 superduplex stainless steel 20 mm in thickness was multi-pass-welded with Gas Metal Arc Welding (GMAW) and Flux-Cored Arc Welding (FCAW) processes. Recommended and higher arc energies and inter-pass temperatures were used.
Maria Asuncion Valiente Bermejo, Kjell Hurtig, Daniel Eyzop, Leif Karlsson   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

T-duality in Massive Integrable Field Theories: The Homogeneous and Complex sine-Gordon Models

, 2004
The T-duality symmetries of a family of two-dimensional massive integrable field theories defined in terms of asymmetric gauged Wess-Zumino-Novikov-Witten actions modified by a potential are investigated. These theories are examples of massive non-linear
Alvarez, Alvarez, Alvarez, Alvarez, Alvarez, Alvarez, Bakas, Bakas, Barashenkov, Barashenkov, Barashenkov, Bardakci, Bars, Bowcock, Buscher, Buscher, Cabra, Cabrera-Carnero, Cabrera-Carnero, Castro Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Castro-Alvaredo, Coleman, Curtright, de Vega, de Vega, de Vega, Dijkgraaf, Dorey, Dorey, Dorey, Fateev, Felder, Fernández-Pousa, Fernández-Pousa, Fernández-Pousa, Ferreira, Ferreira, Gaberdiel, Gawedzki, Gawedzki, Getmanov, Giveon, Giveon, Goddard, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Gomes, Hollowood, Humphreys, J. Luis Miramontes, Karabali, Karabali, Kiritsis, Kiritsis, Korff, Kramers, Leznov, Lund, Lund, Miramontes, Park, Park, Park, Park, Pohlmeyer, Quella, Quella, Witten, Witten, Zamolodchikov, Zamolodchikov   +80 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Study of the Ashkin Teller model with spins S = 1 and σ = 3/2 subjected to different crystal fields using the Monte-Carlo method

Condensed Matter Physics, 2020
Using the Monte-Carlo method, we study the magnetic properties of the Ashkin-Teller model (ATM) under the effect of the crystal field with spins S = 1 and σ = 3/2. First, we determine the most stable phases in the phase diagrams at temperature T= 0 using
Z. Amimer, S. Bekhechi, B.N. Brahmi, R. Boudefla, H. Ez-Zahraouy, A. Rachadi   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Exploration of the High Entropy Alloy Space as a Constraint Satisfaction Problem [PDF]

, 2017
High Entropy Alloys (HEAs), Multi-principal Component Alloys (MCA), or Compositionally Complex Alloys (CCAs) are alloys that contain multiple principal alloying elements. While many HEAs have been shown to have unique properties, their discovery has been
Abu-Odeh, Anas, Arroyave, Raymundo, Chen, Qing, Galvan, Edgar, Kirk, Tanner, Malak, Richard, Mao, Huahai, Mason, Paul   +7 more
core   +1 more source

Close Packing of Atoms, Geometric Frustration and the Formation of Heterogeneous States in Crystals

, 1997
To describe structural peculiarities in inhomogeneous media caused by the tendency to the close packing of atoms a formalism based on the using of the Riemann geometry methods (which were successfully applied lately to the description of structures of ...
A V Trefilov, Collings E W, Conway J H, de Wit R, Eshelby J D, Frank F C, Gornostyrev Yu N, Katsnelson M I, Kléman M, Kléman M, Korsunskii I L, Krivoglaz M A, Kunin I A, M I Katsnelson, Marks L D, Romanov A E, Sadoc J F, Sadoc J F, Sudareva S V, Yu N Gornostyrev   +19 more
core   +1 more source