Determination of Serum/Plasma Concentrations of Psychotropic Drugs in Therapeutic Drug Monitoring [PDF]
The article considers the main methodological methods of therapeutic drug monitoring (TDM) of psychotropic drugs. Analytical methods that allow performing these studies have been described. It has been given the interpretation, examples and brief results
A. I. Platova +2 more
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Effect of Clozapine and 5-NT2A-Antagonist RU-31 on electroencephalography and Motor Activity of Rats in a Model of Schizophrenia with Neonatal Destruction of the Ventral Hippocampus [PDF]
Background. Schizophrenia is a socially signifi cant disease that takes a variety of forms. The form of the course determines prescribing antipsychotic drugs with a different range of clinical effects.
A. A. Spasov +3 more
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Metabolic adverse effects of antipsychotics: the state of the problem and management options [PDF]
Antipsychotic drugs are widely used for many psychiatric disorders, such as schizophrenia, bipolar affective disorder, delusions and hallucinations due to neurological disorders, depression with severe psychotic symptoms.
A. V. Balashova +3 more
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Morphology and Function of Myocardium and Skin Microcirculation 24 Hours after Clozapine Poisoning [PDF]
Aim of the study: to evaluate the effect of sublethal dose of clozapine on the rat cardiovascular system 24 hours after administration of the drug.Materials and methods. The experiments were carried out on 17 male Wistar rats weighing 220-270 g.
A. S. Babkina +6 more
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Pharmacogenetic markers of antipsychotic-induced weight gain: leptin and neuroepeptide Y [PDF]
Antipsychotic drugs are a critical modality in managing of schizophrenia. Although medications can be highly effective, response varies and some patients derive considerably less benefit than others.
K. O. Mironov +3 more
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Клозапин: механизмы токсичности и побочных эффектов [PDF]
Clozapine is an atypical antipsychotic agent with a confirmed effectiveness which is widely used in the clinical practice. However, its administration is associated with a high risk of serious adverse events.
A. M. Golubev +9 more
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Evaluation of the influence of antipsychotics on bone metabolism and characteristics of the body composition in patients with schizophrenia [PDF]
Uvod: Podaci iz literature pokazuju da terapija antipsihoticima može da utiče na koštani metabolizam kod pacijenata sa shizofrenijom. Cilj: Naš cilj je bio da utvrdimo uticaj različitih antipsihotika na metabolizam kostiju, mineralnu koštanu gustinu i ...
Korićanac, Aleksandra P.
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Determination of prevalence and characteristics of drug interactions in patients with psychiatric disease [PDF]
Увод: Бележи се пораст јављања менталних болести, па чак 1 од 8 особа живи са неким менталним поремећајем. Лекови који проналазе јединствену улогу у лечењу истих јесу антипсихотици, међу којима клозапин чини основу терапије на третман резистентне ...
Plankoš, Aleksandar
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The phenomenon of therapeutic resistance in the treatment of schizophrenia: the possibilities of modern diagnostics and methods of anti-resistant effects [PDF]
The formation of resistance is a key factor in curbing progress in the treatment of schizophrenia. In modern psychiatric practice, despite the emergence of new medical technologies, including the use of a wide arsenal of psychotropic medicinal effects ...
E. V. Bigday +3 more
core +2 more sources
Аssessment of adequacy of prescribing therapy in the elderly with cardiovascular diseases [PDF]
Cilj: Istraživanje koje je vršeno imalo je za cilj da odredi prevalencu PIM-a u populaciji starih ispitanika koji su imali dijagnostikovano kardiovaskularno oboljenje i da kvantifikuje značaj određenih varijabli na prisustvo PIM-a. Metoda: Sprovedena
Stojanović, Goran
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