Determination of Serum/Plasma Concentrations of Psychotropic Drugs in Therapeutic Drug Monitoring [PDF]
, 2021 The article considers the main methodological methods of therapeutic drug monitoring (TDM) of psychotropic drugs. Analytical methods that allow performing these studies have been described. It has been given the interpretation, examples and brief results
A. I. Platova +2 more
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Effect of Clozapine and 5-NT2A-Antagonist RU-31 on electroencephalography and Motor Activity of Rats in a Model of Schizophrenia with Neonatal Destruction of the Ventral Hippocampus [PDF]
, 2022 Background. Schizophrenia is a socially signifi cant disease that takes a variety of forms. The form of the course determines prescribing antipsychotic drugs with a different range of clinical effects.
A. A. Spasov +3 more
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Morphology and Function of Myocardium and Skin Microcirculation 24 Hours after Clozapine Poisoning [PDF]
, 2020 Aim of the study: to evaluate the effect of sublethal dose of clozapine on the rat cardiovascular system 24 hours after administration of the drug.Materials and methods. The experiments were carried out on 17 male Wistar rats weighing 220-270 g.
A. S. Babkina +6 more
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Metabolic adverse effects of antipsychotics: the state of the problem and management options [PDF]
, 2023 Antipsychotic drugs are widely used for many psychiatric disorders, such as schizophrenia, bipolar affective disorder, delusions and hallucinations due to neurological disorders, depression with severe psychotic symptoms.
A. V. Balashova +3 more
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Клозапин: механизмы токсичности и побочных эффектов [PDF]
, 2018 Clozapine is an atypical antipsychotic agent with a confirmed effectiveness which is widely used in the clinical practice. However, its administration is associated with a high risk of serious adverse events.
A. M. Golubev +9 more
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Pharmacogenetic markers of antipsychotic-induced weight gain: leptin and neuroepeptide Y [PDF]
, 2021 Antipsychotic drugs are a critical modality in managing of schizophrenia. Although medications can be highly effective, response varies and some patients derive considerably less benefit than others.
K. O. Mironov +3 more
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The phenomenon of therapeutic resistance in the treatment of schizophrenia: the possibilities of modern diagnostics and methods of anti-resistant effects [PDF]
, 2023 The formation of resistance is a key factor in curbing progress in the treatment of schizophrenia. In modern psychiatric practice, despite the emergence of new medical technologies, including the use of a wide arsenal of psychotropic medicinal effects ...
E. V. Bigday +3 more
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Морфологические и функциональные изменения сердечно-сосудистой системы при остром отравлении клозапином (экспериментальное исследование) [PDF]
, 2019 Purpose of the study. To evaluate the influence of sublethal dose of Clozapine on the functional and morphological parameters of the cardiovascular system in rats 4 hrs. after the drug administration.Materials and methods.
A. Asanov R. +13 more
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Evaluation of the influence of antipsychotics on bone metabolism and characteristics of the body composition in patients with schizophrenia [PDF]
, 2023 Uvod: Podaci iz literature pokazuju da terapija antipsihoticima može da utiče na koštani metabolizam kod pacijenata sa shizofrenijom. Cilj: Naš cilj je bio da utvrdimo uticaj različitih antipsihotika na metabolizam kostiju, mineralnu koštanu gustinu i ...
Korićanac, Aleksandra P.
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Trend upotrebe psihotropnih lekova kod članova porodica vojnih lica [PDF]
, 2013 Uvod. Osobe u sistemu vojnog zdravstva predstavljaju jednu od specifičnih populacija stanovništva, koja obuhvata osobe širokih dobnih kategorija i profesionalnih zaduženja, uključujući aktivni i penzionisani sastav.
Jovičić, Uglješa B.
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