Results 11 to 20 of about 129 (105)

КЛОПИДОГРЕЛ ПРИ ПЛАНОВОЙ РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА

open access: yes, 2016
The article focuses on the practical issues of selective revascularization of myocardium, including the specifics of procedure and patients characteristics, whom this intervention is at most indicated.
Наталья Вадимовна Теплова
semanticscholar   +1 more source

RESISTANCE TO ANTIPLATELET DRUGS (ASPIRIN, CLOPIDOGREL) IN PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To study prevalence of resistance to acetylsalicylic acid, clopidogrel and dual resistance in percutaneous coronary intervention (PCI), to identify clinical risk factors of resistance development, to study effects of concomitant therapy on ...
V. A. Sulimov, E. V. Moroz
doaj   +1 more source

МОЖЕТ ЛИ КЛОПИДОГРЕЛ В ПОЛНОЙ МЕРЕ ЗАМЕНИТЬ ВАРФАРИН И ДАБИГАТРАН ПРИ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ

open access: yes, 2013
Commentary on the paper “Age and effectiveness and safety of various antithrombotic therapy variants in patients with nonvalvular atrial fibrillation” by Shevelev V. I. and Kanorskyi S. G. (Cardiovascular Therapy and Prevention 2013;12 (1):46–53).
А. Б. Сумароков
semanticscholar   +1 more source

Ассоциация генетических детерминант метаболизма клопидогрела и клинических показателей сердечно-сосудистого риска у пациентов бурятской национальности

open access: yesПатология кровообращения и кардиохирургия, 2019
Актуальность. У части пациентов наблюдаются изменения активности клопидогрела за счет полиморфных вариантов rs4244285(*2), rs4986893 (*3), rs12248560 (*17) в гене цитохрома CYP2C19, влияющих на метаболизм.
Е. Зеленская   +6 more
doaj   +1 more source

СONCOMITANT ADMINISTRATION OF CLOPIDOGREL AND PROTON PUMP INHIBITORS: ARE THERE ANY OPEN QUESTIONS LEFT TODAY?

open access: yesРациональная фармакотерапия в кардиологии, 2015
Concomitant administration of clopidogrel and proton pump inhibitors (PPI), the possible influence of PPI on the effectiveness of clopidogrel often raises questions among practitioners.
S. Yu. Martsevich, A. Yu. Suvorov
doaj   +1 more source

A clinical case of acute coronary syndrome in patients with type 2 diabetes

open access: yesМедицинский совет, 2015
The article reviews a clinical cases of acute coronary syndrome in a patient with type 2 diabetes (T2D). The causes of progression of atherosclerosis in patients with T2D are considered which leads to myocardial ischemia against a background of ...
S. V. Kakorin, E. N. Kononets
doaj   +1 more source

INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. Carriership of CYP2C19*2 allelic variant and reduced CYP3A4 activity can affect the formation of clopidogrel’s active metabolite and, respectively, its antiplatelet effect.
K. B. Mirzaev   +4 more
doaj   +1 more source

Morphological determinants for the local hemostatic effect of exogenous fibrin monomer in its systemic administration after injury with inhibition of platelet aggregation in the experiment

open access: yesActa Biomedica Scientifica, 2023
Background. In our previously published studies, we demonstrated a high hemostatic activity of a low dose of exogenous fibrin monomer during its systemic administration in a model of dosed liver injury with preliminary inhibition of platelet aggregation.
V. M. Vdovin   +6 more
doaj   +1 more source

ДВОЙНАЯ АНТИТРОМБОЦИТАРНАЯ ТЕРАПИЯ: НЕОБХОДИМОСТЬ ПРИВЕРЖЕННОСТИ К ЛЕЧЕНИЮ И ВОЗМОЖНОСТИ ЕЕ ПОВЫШЕНИЯ

open access: yesАтеротромбоз, 2014
Статья посвящена обсуждению вопросов приверженности к применению двойной антитромбоцитарной терапии (ДАТ) у пациентов, перенесших острый коронарный синдром (ОКС) или перенесших коронарное стентирование.

doaj   +1 more source

EVALUATION OF PLATELET AGGREGATION IN CLINICAL PRACTICE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Evaluation of platelet function with subsequent modification of antiplatelet therapy regimen is one of the areas of personalized medicine. Analysis of the causes of inadequate antiplatelet action of clopidogrel, the association of residual platelet ...
K. B. Mirzaev   +2 more
doaj   +1 more source

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