Results 1 to 10 of about 148,576 (255)

Clopidogrel resistance and its relevance: Current concepts

Journal of Family Medicine and Primary Care
Clopidogrel is the most widely used P2Y12 receptor inhibitor (P2Y12i) as a part of dual antiplatelet therapy along with aspirin. Clopidogrel is a pro-drug and is metabolized to its active metabolite by the hepatic enzyme cytochrome P4502C19 (CYP2C19 ...
Akshyaya Pradhan, Monika Bhandari, Pravesh Vishwakarma, Rishi Sethi   +3 more
doaj   +1 more source

Clopidogrel Bisulfate [PDF]

, 2010
Maria L A D, Lestari, , Suciati, Gunawan, Indrayanto, Harry G, Brittain   +3 more
openaire   +2 more sources

Clopidogrel Management in Abdominal Surgery: A Comparison of Perioperative Bleeding Risks with Low-Molecular-Weight Heparin Bridging, No-Bridging and Clopidogrel Continuation Strategies

Clinical and Applied Thrombosis/Hemostasis
Clopidogrel is usually discontinued 5–7 days before elective surgery to reduce the risk of bleeding. However, the perioperative safety of patients receiving low-molecular-weight heparin (LMWH) bridging therapy or continuing clopidogrel therapy remains ...
Bangsheng Hu MD, Junsheng Chen MD, Shuai Han MD, Zeping Dai MD, PhD, Ju Gao MD, PhD   +4 more
doaj   +1 more source

The effect of concurrent clopidogrel and omeprazole administration on clopidogrel metabolism and platelet function in healthy cats

Journal of Veterinary Internal Medicine
Background Some studies in humans show that the concurrent use of clopidogrel and omeprazole decreases plasma clopidogrel active metabolite (CAM) concentrations and clopidogrel antiplatelet effects. Whether this drug interaction occurs in cats is unknown.
Christina Plante, Pamela M. Lee, Jillian M. Haines, O. Lynne Nelson, Stephanie E. Martinez, Michael H. Court   +5 more
doaj   +1 more source

The association of ABCB1, CYP2C19 and CYP2C9 combined activity with clopidogrel resistance in patients with recurrent ischemic stroke. [PDF]

Pharmacogenomics J
Deiman B, Hermans M, de Rijk M, Bras A, Scharnhorst V.   +4 more
europepmc   +1 more source

Clopidogrel vs. Aspirin in Double Antithrombotic Therapy for Patients on Oral Anticoagulation Undergoing Coronary Stenting. [PDF]

J Cardiovasc Dev Dis
Pompei G, Arioti M, Moretti C, Bendandi F, Panevino R, Sanna S, Casu G, Rubboli A.   +7 more
europepmc   +1 more source

Role of thromboelastography in risk stratifying patients with traumatic brain injury on prehospital antiplatelet agents. [PDF]

Trauma Surg Acute Care Open
Okonya T, Gulati S, Reeson EA, Mailolo JK, Rahaman CA, Warrington NV, Matthees NG, Low TM, Kupanoff KM, Weinberg JA, Bogert JN.   +10 more
europepmc   +1 more source

Clopidogrel, an ADP-P2Y12 Receptor Antagonist, Is Associated With Lower Opioid Consumption and a Reduced Incidence of Delirium in Cancer Patients Receiving Chemotherapy: A Nationwide Retrospective Cohort Study in Japan. [PDF]

Neuropsychopharmacol Rep
Abe H, Inoue R, Kogure T, Tsuchida R, Owada H, Sudo Y, Yokoshima Y, Matsui H, Yasunaga H, Sumitani M.   +9 more
europepmc   +1 more source

ABCD-GENE Score Stratifying Risk-Benefit Profile of Clopidogrel-Aspirin Therapy in Ischemic Stroke Within 24-72 Hours. [PDF]

J Stroke
Chen Y, Jiang L, Gao Y, Chen W, Yan H, Wang T, Yang Y, Pan Y, Wang Y.   +8 more
europepmc   +1 more source

Limited Visibility and Perception of the Clinical Relevance of Clopidogrel Pharmacogenetics in Cardiology Literature. [PDF]

Clin Transl Sci
Dello Russo C, Venetucci L, Akintola A, Gagliardi D, Ramlogan R, Pirmohamed M.   +5 more
europepmc   +1 more source