Results 1 to 10 of about 12,121 (179)

Stroke following percutaneous coronary intervention : type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12 [PDF]

, 2016
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015.
Berry, Colin, British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research, Buchan, Iain, de Belder, Mark A, Keavney, Bernard, Kontopantelis, Evangelos, Kwok, Chun Shing, Ludman, Peter F, Mamas, Mamas A, Myint, Phyo K, Nolan, Jim, Zaman, Azfar   +11 more
core   +1 more source

Efficacy of aspirin, clopidogrel, and ticlopidine in stroke prevention: A population-based case-cohort study in Taiwan.

PLoS ONE, 2020
BackgroundIn real-world practice settings, there is insufficient evidence on the efficacy of antiplatelet drugs, including clopidogrel, aspirin, and ticlopidine, in stroke prevention.PurposeTo compare the efficacies between aspirin and clopidogrel and ...
Yi-Sin Wong, Ching-Fang Tsai, Yueh-Han Hsu, Cheung-Ter Ong   +3 more
doaj   +1 more source

Repurposing the Antiplatelet Agent Ticlopidine to Counteract the Acute Phase of ER Stress Condition: An Opportunity for Fighting Coronavirus Infections and Cancer

Molecules, 2022
Different pathological conditions, including viral infections and cancer, can have a massive impact on the endoplasmic reticulum (ER), causing severe damage to the cell and exacerbating the disease.
Anna Tesei, Michela Cortesi, Martina Bedeschi, Noemi Marino, Giacomo Rossino, Roberta Listro, Daniela Rossi, Pasquale Linciano, Simona Collina   +8 more
doaj   +1 more source

A Paclitaxel-Eluting Stent for the Prevention of Coronary Restenosis [PDF]

, 2003
Background Intimal hyperplasia and resulting restenosis limit the efficacy of coronary stenting. We studied a coronary stent coated with the antiproliferative agent paclitaxel as a means of preventing restenosis.
Choi, D, Ho, DSW, Hong, MK, Jang, Y, Lam, R, Lee, CW, Mintz, GS, Park, SJ, Park, SW, Raizner, AE, Shim, WH, Weissman, NJ   +11 more
core   +1 more source

Sensitive Voltammetric Determination of Ticlopidine in Pharmaceuticals Employing a Multi-Walled Carbon Nanotubes Paste Electrode

Orbital: The Electronic Journal of Chemistry, 2016
A sensitive analytical procedure has been developed for the determination of ticlopidine using a multi-walled carbon nanotubes paste electrode (MWCNTsPE). Direct oxidation of analyte was observed by cyclic voltammetry as evidenced by the presence of well-
Igor Rebech, Jessica Scremin, César Ricardo Teixeira Tarley, Elen Romão Sartori   +3 more
doaj   +3 more sources

Highly productive and scalable approach to synthesize ticlopidine: A potent thienopyridine anti-platelet aggregation drug

Heliyon, 2020
Ticlopidine (trade name Ticlid), an acidic thienopyridine derivative, is an effective, well-known and long-acting inhibitor of platelet aggregation.
Muhammad Faisal, Quret ul Aein, Aamer Saeed, Amara Mumtaz, Fayaz Ali Larik   +4 more
doaj   +1 more source

Determination of ticlopidine in human plasma by capillary gas chromatography with ion trap detection [PDF]

, 2003
A gas chromatographic method for determination of ticlopidine in human plasma using mass spectrometric detection was developed. A Perkin Elmer model 8500 gas chromatograph coupled to an ion trap detector (ITD) in electron impact mode (EI) was used.
Lino, Celeste, Pena, Angelina, Silveira, M. Irene N.   +2 more
core   +1 more source

Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1

Mediators of Inflammation, 2014
Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer.
Joanna Lecka, Michel Fausther, Beat Künzli, Jean Sévigny   +3 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Agranulocytosis and hepatic toxicity with ticlopidine therapy: a case report

Journal of Medical Case Reports, 2010
Introduction Ticlopidine is a platelet inhibitor used to prevent thrombosis in patients with cerebrovascular or coronary artery disease. The most common side effects are mild and transitory: diarrhea, dyspepsia, nausea and rashes.
Previtera Antonino M, Pagani Rossella
doaj   +1 more source