Results 1 to 10 of about 4,436,997 (314)
Antiplatelet drugs and liver fibrosis [PDF]
Liver fibrosis results from an imbalance between extracellular matrix formation and degradation. The background of liver fibrosis is chronic inflammation and subsequent microcirculation disturbance including microthrombosis.
Pamela Czajka +7 more
doaj +5 more sources
SummaryPlatelets play a major role in thromboembolic diseases, and so antiplatelet therapy remains crucial in treatment and prophylaxis. Upon vascular injury, platelets rapidly adhere to the exposed subendothelial matrix, after which they become activated, resulting in the recruitment of additional platelets from the circulation to eventually form a ...
Simon F, De Meyer +4 more
semanticscholar +9 more sources
The Impact of Preinjury Use of Antiplatelet Drugs on Outcomes of Traumatic Brain Injury: A Systematic Review and Meta-Analysis [PDF]
ObjectiveThe study aimed to compare outcomes of traumatic brain injury (TBI) in patients on pre-injury antiplatelet drugs vs. those, not on any antiplatelet or anticoagulant drugs.MethodsPubMed, Embase, and Google Scholar databases were searched up to ...
Li Cheng, Gaoliang Cui, Rong Yang
doaj +3 more sources
Pharmacogenetics of Antiplatelet Drugs [PDF]
Pharmacogenetics refers to the genetic factors that influence the response to a drug, often involving genetic variations in drug metabolizing enzymes. The pharmacogenetics of antiplatelet agents is in its infancy and largely reflects variations in drug ...
Ronan Curtin, Desmond J. Fitzgerald
doaj +5 more sources
When and How to Combine Antiplatelet and Anticoagulant Drugs?
Antiplatelet and anticoagulant drugs work at different places in the coagulation system. Antiplatelet drugs are usually indicated in patients with atherosclerosis.
C. Espinola-Klein
exaly +2 more sources
Efficacy, Safety, and Role of Antiplatelet Drugs in the Management of Acute Coronary Syndrome: A Comprehensive Review of Literature [PDF]
Acute coronary syndrome (ACS) is a complex condition characterized by myocardial ischemia or infarction which can lead to significant morbidity and death. Antiplatelet drugs play a crucial role in the management of ACS and have been shown to minimize the
M. Abubakar +7 more
semanticscholar +2 more sources
Summary Background The risk of death from spontaneous intracerebral haemorrhage is increased for people taking antiplatelet drugs. We aimed to assess the feasibility of randomising patients on antiplatelet drug therapy with spontaneous intracerebral ...
M. Desborough +23 more
semanticscholar +2 more sources
Influence of Genetic and Epigenetic Factors of P2Y12 Receptor on the Safety and Efficacy of Antiplatelet Drugs [PDF]
P2Y12 receptor inhibitors are drugs that decrease the risk of stent thrombosis and lower the long-term risk of non-stent-related myocardial infarction and stroke.
D. Danielak +3 more
semanticscholar +2 more sources
British Journal of Pharmacology (2006) 147, S241–S251.
Gustav, Born, Carlo, Patrono
+6 more sources
Antiplatelet drug interactions [PDF]
Abstract. Mackenzie IS, Coughtrie MWH, MacDonald TM, Wei L. (Medicines Monitoring Unit (MEMO); and Centre for Oncology & Molecular Medicine, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School; Dundee, UK). Antiplatelet drug interactions (Review‐Symposium).
Mackenzie, I. S. +3 more
openaire +3 more sources

