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Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications
Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent) venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a century, and, nowadays, physicians possess a broad panel of multiple ...
Geraldine Poenou +2 more
exaly +4 more sources
Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants
Background Lupus anticoagulants (LA) are one laboratory criterion for classification of antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal morbidity being clinical criteria. The presence of LA is detected (or excluded)
Emmanuel J. Favaloro, Leonardo Pasalic
doaj +3 more sources
Anticoagulants and Osteoporosis [PDF]
Anticoagulant agents are widely used in the treatment of thromboembolic events and in stroke prevention. Data about their effects on bone tissue are in some cases limited or inconsistent (oral anti-vitamin K agents), and in others are sufficiently strong
S. Signorelli +5 more
semanticscholar +3 more sources
A Study of Using Anticoagulants in a Tertiary Care Hospital in Bangalore: A Prospective Study [PDF]
Background: drug utilization studies are necessary to evaluate the rational use and associated risks of anticoagulants. This study aimed to identify drug utilization pattern and possible drug interactions with the use of anticoagulants in a tertiary care
Shahrzad Raouf +3 more
doaj +1 more source
A post-COVID patient with a high D-dimer Value (>5000 IU) was posted for total knee replacement. She was on multiple anticoagulants including the novel oral anticoagulants that started to reduce thrombotic risk.
Balasubramaniam Gayathri +3 more
doaj +1 more source
Safety and interaction of direct oral anticoagulants with antiarrhythmic drugs
The use of direct oral anticoagulants minimized the risks associated with vitamin K antagonist (warfarin) therapy. Currently, direct oral anticoagulants have priority over warfarin for the prevention of thromboembolic events in patients with atrial ...
B. A. Tatarsky, N. V. Kazyonnova
doaj +1 more source
Key Points Question Is the recent use of direct oral anticoagulants (confirmed ingestion within 48 hours) associated with increased risk of symptomatic intracranial hemorrhage following intravenous thrombolysis for ischemic stroke?
T. Meinel +224 more
semanticscholar +1 more source
IMPACT OF NON-VITAMIN K ORAL ANTI-COAGULANTS ON WARFARIN UTILISATION AND NHS BUDGET IN UK
Introduction: Vitamin K anticoagulants were the mainstay prophylaxis of stroke in patients with atrial fibrillation and thromboembolic diseases. Non-vitamin K oral anticoagulants were approved for use in UK.
Mohammed Aladul +2 more
doaj +1 more source
Effects of sufficient anticoagulation on ischemic stroke outcomes in patients with nonvalvular atrial fibrillation [PDF]
Background Optimal anticoagulation therapy reduces the risk of ischemic stroke in patients with nonvalvular atrial fibrillation (AF). Therefore, we aimed to evaluate the effects of prior anticoagulation therapy with vitamin K antagonists (VKAs) and ...
Tae Jung Kim +3 more
doaj +1 more source
Anticoagulants for people hospitalised with COVID-19.
BACKGROUND The primary manifestation of coronavirus disease 2019 (COVID-19) is respiratory insufficiency that can also be related to diffuse pulmonary microthrombosis and thromboembolic events, such as pulmonary embolism, deep vein thrombosis, or ...
Ronald Lg Flumignan +9 more
semanticscholar +1 more source

