Results 31 to 40 of about 261,124 (307)

Impact of Alteplase on Mortality in Critically Ill Patients with COVID-19 and Pulmonary Embolism

Viruses, 2023
COVID-19 is an independent risk factor for pulmonary embolism (PE). Little is known about alteplase therapy in this patient group. A retrospective study analyzed 74 patients with PE and acute respiratory distress syndrome (ARDS) due to COVID-19 who were ...
Oleksandr Valentynovych Oliynyk, Marta Rorat, Serhij Oleksandrovych Solyarik, Vitaliy Andrijovych Lukianchuk, Serhij Oleksandrovych Dubrov, Vitaliy Hrygorovych Guryanov, Yanina Volodymyrivna Oliynyk, Svitlana Mykolaivna Yaroslavskaya, Roman Szalast, Wojciech Barg   +9 more
doaj   +1 more source

Commonly Prescribed Anticoagulants Exert Anticancer Effects in Oral Squamous Cell Carcinoma Cells In Vitro

Biology, 2022
Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer. With anticoagulant usage on the rise, it is important to elucidate their potential effects on tumour biology and interactions with chemotherapeutics.
Li-Qiao R. Ling, Zichen Lin, Rita Paolini, Camile S. Farah, Michael McCullough, Mathew A. W. T. Lim, Antonio Celentano   +6 more
doaj   +1 more source

Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians

Journal of Thrombosis and Haemostasis, 2018
Click to hear Dr Baglin's perspective on the role of the laboratory in treatment with new oral ...
J. Douxfils, W. Ageno, C. Samama, Lessire Sarah, H. T. Cate, Peter, Verhamme, J. Dogné, F. Mullier   +8 more
semanticscholar   +1 more source

Is the time in therapeutic range on coumarins predicted by previous time in therapeutic range?

Research and Practice in Thrombosis and Haemostasis, 2020
Background The benefit of vitamin K antagonists depends on the time within the therapeutic range (TTR). A patient’s previous TTR could be a factor in the decision to change the anticoagulation regimen.
Jasper H. A. vanMiert, Nic J. G. M. Veeger, Karina Meijer   +2 more
doaj   +1 more source

Low Exposure to Direct Oral Anticoagulants Is Associated with Ischemic Stroke and Its Severity [PDF]

Journal of Stroke, 2022
Background and purpose In acute stroke patients, plasma concentrations of direct oral anticoagulants (DOAC) at hospital admission only poorly mirror DOAC exposure or the coagulation status at the time of the event.
Timolaos Rizos, Andreas D. Meid, Andrea Huppertz, Chris Dumschat, Jan Purrucker, Kathrin I. Foerster, Jürgen Burhenne, David Czock, Ekkehart Jenetzky, Peter A. Ringleb, Walter E. Haefeli   +10 more
doaj   +1 more source

New anticoagulants: Moving beyond the direct oral anticoagulants

Journal of Thrombosis and Haemostasis, 2020
Although anticoagulants have been in use for more than 80 years, heparin and vitamin K antagonists were the sole available options until recently. Although these agents revolutionized the prevention and treatment of thrombotic diseases, their use has ...
J. Fredenburgh, J. Weitz
semanticscholar   +1 more source

Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy [PDF]

Кардіохірургія та інтервенційна кардіологія, 2021
Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is
V.О. Yarosh, V.V. Babenko, O.E. Svyrydiuk, O.J. Zharinov, O.A. Yepanchintseva, B.M. Todurov   +5 more
doaj   +1 more source

Effectiveness and safety of reduced dose non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study

British medical journal, 2017
Objective To examine clinical effectiveness and safety of apixaban 2.5 mg, dabigatran 110 mg, and rivaroxaban 15 mg compared with warfarin among patients with atrial fibrillation who had not previously taken an oral anticoagulant.
P. Nielsen, F. Skjøth, M. Søgaard, J. N. Kjældgaard, G. Lip, T. Larsen   +5 more
semanticscholar   +1 more source

Atrial Fibrillation on Patients with Vascular Dementia: A Fundamental Target for Correct Management

Brain Sciences, 2020
Background: Atrial fibrillation (AF) is a risk factor for cerebrovascular diseases and vascular dementia (VAD). The aim of this study was to evaluate the effect of the adherence to anticoagulant therapy guidelines in patients with dementia and AF on the ...
Giovanna Viticchi, Lorenzo Falsetti, Marco Burattini, Vincenzo Zaccone, Laura Buratti, Marco Bartolini, Gianluca Moroncini, Mauro Silvestrini   +7 more
doaj   +1 more source

Effectiveness and Safety of Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients

Stroke, 2018
Background and Purpose— This ARISTOPHANES study (Anticoagulants for Reduction in Stroke: Observational Pooled Analysis on Health Outcomes and Experience of Patients) used multiple data sources to compare stroke/systemic embolism (SE) and major bleeding ...
G. Lip, A. Keshishian, Xiaoyan Li, M. Hamilton, C. Masseria, K. Gupta, Xuemei Luo, J. Mardekian, K. Friend, A. Nadkarni, Xianying Pan, O. Baser, S. Deitelzweig   +12 more
semanticscholar   +1 more source