Role of ticlopidine for prevention of stroke. [PDF]
, 1992 Ticlopidine, an antiplatelet agent with a unique mechanism of action, is now available for clinical use in the United States and Canada. Recently two large randomized trials demonstrated that ticlopidine can reduce the risk of subsequent stroke
G W Albers
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Jurnal Farmasi Sains dan Komunitas, 2017 Clopidogrel, an antithrombotic drug, has been proven by FDA as Plavix® was initially used for the prevention of vascular occlusive that cause of myocardial infarction, stroke, and vascular death in patients with atherosclerosis and then it is used to ...
Titien Siwi Hartayu, Dewi Setyaningsih
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The effect of antiaggregational therapy on the long-term patency of the femoropopliteal/crural bypass [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2012 Introduction. Antiaggregational therapy can reduce thrombosis development following the arterial reconstruction surgery. In most cases acetylsalicylic acid and ticlopidine are used as antiaggregational agents. Objective.
Vasić Dragan +3 more
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Abciximab, ticlopidine, and concomitant abciximab-ticlopidine therapy: Ex vivo platelet aggregation inhibition profiles in patients undergoing percutaneous coronary interventions [PDF]
, 2000 Background We examined the ex vivo platelet aggregation profiles of patients who underwent percutaneous coronary intervention and received either abciximab, ticlopidine, or both agents.Study Design and Methods The trial was a prospective, nonrandomized ...
Maresh, K +8 more
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Drug Interaction between Ticlopidine and Cyclosporine [PDF]
, 2001 INTRODUCTIONCyclosporine is an immunosuppressant that is widely used for patients undergoing organ transplantation. Optimal long-term use of the drug entails careful monitoring of blood or plasma concentrations.1 The concurrent administration of other ...
Hollomby, David J. +2 more
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Metabolism of Ticlopidine in Rats: Identification of the Main Biliary Metabolite as a Glutathione Conjugate of Ticlopidine S-Oxide [PDF]
, 2020 : We have identified several novel metabolites of ticlopidine, a well known antiplatelet agent and have revealed its metabolic route in rats. The main biliary metabolite of ticlopidine was characterized as a glutathione (GSH) conjugate of ticlopidine S ...
Yuko Fujimaki +5 more
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Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2023 To reduce pharmacy-related medical expenses, it is necessary to reduce drug costs. One way to achieve this is by increasing the usage rate of generic drugs.
Takaaki Suzuki BS +9 more
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Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
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BMC Neurology, 2021 Background Antiplatelet drugs may prevent recurrent ischemic events after ischemic stroke but their relative effectiveness and harms still need to be clarified.
Cinzia Del Giovane +4 more
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Ticlopidine increases nitric oxide generation in heart-transplant recipients: a possible novel property of ticlopidine. [PDF]
, 1998 International audienceThe objective of this study was to evaluate the effects of ticlopidine on the generation of eicosanoids and nitric oxide in heart-transplant recipients.
Delaye, J. +6 more
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