Results 31 to 40 of about 6,879 (152)

Detecting Adverse Drug Events Through the Chronological Relationship Between the Medication Period and the Presence of Adverse Reactions From Electronic Medical Record Systems: Observational Study

JMIR Medical Informatics, 2021
BackgroundMedicines may cause various adverse reactions. An enormous amount of money and effort is spent investigating adverse drug events (ADEs) in clinical trials and postmarketing surveillance.
Kei Teramoto, Toshihiro Takeda, Naoki Mihara, Yoshie Shimai, Shirou Manabe, Shigeki Kuwata, Hiroshi Kondoh, Yasushi Matsumura   +7 more
doaj   +1 more source

Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting

Frontiers in Neurology, 2019
Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung, Suk Jae Kim, Jaechun Hwang, Mi Ji Lee, Jun Lee, Kyung-Yul Lee, Man-Seok Park, Sang Min Sung, Keon Ha Kim, Pyoung Jeon, Oh Young Bang   +10 more
doaj   +1 more source

THE EFFECTIVENESS OF CLOPIDOGREL AS AN ANTITHROMBOTIC COMPARED TO TICLOPIDINE AND ASPIRIN (META-ANALYSIS)

Jurnal Farmasi Sains dan Komunitas, 2017
Clopidogrel, an antithrombotic drug, has been proven by FDA as Plavix® was initially used for the prevention of vascular occlusive that cause of myocardial infarction, stroke, and vascular death in patients with atherosclerosis and then it is used to ...
Titien Siwi Hartayu, Dewi Setyaningsih
doaj   +1 more source

The effect of antiaggregational therapy on the long-term patency of the femoropopliteal/crural bypass [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2012
Introduction. Antiaggregational therapy can reduce thrombosis development following the arterial reconstruction surgery. In most cases acetylsalicylic acid and ticlopidine are used as antiaggregational agents. Objective.
Vasić Dragan, Radmili Oliver, Davidović Lazar, Vraneš Milica   +3 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Study of Factors to Increase the Usage Rate of Generic Drugs in Platelet Aggregation Inhibitors

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2023
To reduce pharmacy-related medical expenses, it is necessary to reduce drug costs. One way to achieve this is by increasing the usage rate of generic drugs.
Takaaki Suzuki BS, Mari Iwata BS, Mika Maezawa MS, Kiyoka Matsumoto BS, Mizuki Tanaka BS, Riko Satake BS, Misaki Inoue BS, Yu Yoshida BS, Kazuhiro Iguchi PhD, Mitsuhiro Nakamura PhD   +9 more
doaj   +1 more source

Ticlopidine-induced cholestatic hepatitis: A case report and review of the literature

Italian Journal of Medicine, 2012
Introduction Cholestatic hepatitis is frequently a drug-related syndrome. We describe the case of a 57-year-old man who developed cholestatic hepatitis two months after starting therapy with ticlopidine following a carotid endarterectomy.Materials and ...
Luigi Anastasio, Valerio Manno, Maria Carbone, Nicola Lentini, Sandro Baldari, Lucia Sofia, Giuseppe Topa, Antonio Arone   +7 more
doaj   +1 more source

Antiplatelet drugs for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis

BMC Neurology, 2021
Background Antiplatelet drugs may prevent recurrent ischemic events after ischemic stroke but their relative effectiveness and harms still need to be clarified.
Cinzia Del Giovane, Giorgio B. Boncoraglio, Lorenza Bertù, Rita Banzi, Irene Tramacere   +4 more
doaj   +1 more source

Incidence of neutropenia in patients with ticlopidine/Ginkgo biloba extract combination drug for vascular events: A post-marketing cohort study.

PLoS ONE, 2019
Background and purposeThe ticlopidine/Ginkgo biloba ext. combination drug (Yuclid) is used as an antiplatelet agent for prevention of vascular events since its approval in 2008.
Han-Gil Jeong, Jae Sun Yoon, Juneyoung Lee, Hee-Joon Bae   +3 more
doaj   +1 more source

Is clopidogrel superior to aspirin in secondary prevention of vascular disease?

Current Controlled Trials in Cardiovascular Medicine, 2000
The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events trial ...
Algra Ale, van Gijn Jan
doaj   +1 more source