Results 51 to 60 of about 6,879 (152)

Ticagrelor: A Reversible P2Y12 Inhibitor in Preventionof Thrombotic Events

open access: yesRUHS Journal of Health Sciences, 2023
Antiplatelet drugs play a crucial role in patients of coronary artery diseases, cerebrovascular diseases, and maintaining the patency of revascularised arteries and stents after coronary angioplasty.
Uma Advani , Charu Jain , Alka Bansal , Neha Sharma , Kopal Sharma
doaj   +1 more source

ANTITHROMBOTIC THERAPY OF ISCHEMIC HEART DISEASE: FROM FAST ACTING ANTIAGGREGANTS TO STATINES AND NITRATE OXIDE. IS IT REAL?

open access: yesРациональная фармакотерапия в кардиологии, 2016
Mechanisms of atherothrombosis in atherosclerosis of coronary arteries are described. Mechanism of action and clinical efficiency of antithrombotic and antiplatelet medicines such as acetylsalicylic acid, warfarin, ticlopidine and clopidogrel are ...
I. A. Latfullin, A. A. Podolskaya
doaj   +1 more source

Influence of Sodium Bicarbonate on Wall Teichoic Acid Synthesis and β-Lactam Sensitization in NaHCO3-Responsive and Nonresponsive Methicillin-Resistant Staphylococcus aureus

open access: yesMicrobiology Spectrum, 2022
Methicillin-resistant Staphylococcus aureus (MRSA) strains pose major treatment challenges due to their innate resistance to most β-lactams under standard in vitro antimicrobial susceptibility testing conditions.
Selvi C. Ersoy   +9 more
doaj   +1 more source

Synthesis, X‐Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
Two new thiophene–pyrazole derivatives, 8a and 8b, were synthesized from thiophene 3 precursor and fully characterized. The structure of 8a was confirmed by single‐crystal X‐ray diffraction, which revealed a nonplanar conformation stabilized by NH···O hydrogen bonding and weak intermolecular contacts.
Abdullatif Bin Muhsinah   +3 more
wiley   +1 more source

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4728-4740, June 2026.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang   +5 more
wiley   +1 more source

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 3, Page 883-892, May 2026.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori   +9 more
wiley   +1 more source

Platelet‐Activating Factor Pathway in Women With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity

open access: yesObesity, Volume 34, Issue 5, Page 1056-1067, May 2026.
Increased hepatic PAFR expression in MASLD is associated with histological disease severity and may contribute to progression through platelet activation, whereas circulating Lp‐PLA2 levels lack discriminatory value as a noninvasive biomarker. ABSTRACT Objective This study aimed to investigate the platelet‐activating factor (PAF) pathway in obesity ...
Joan Duran‐Bertran   +11 more
wiley   +1 more source

Antiplatelet combinations for prevention of atherothrombotic events

open access: yesVascular Health and Risk Management, 2011
Mario Bollat,i Fiorenzo Gaita, Matteo AnselminoDepartment of Internal Medicine, Division of Cardiology, University of Torino, ItalyAbstract: Antiplatelet therapy plays a fundamental role in reducing atherothrombotic events by several pathways.
Anselmino M, Bollati M, Gaita F
doaj  

Fibroelastoma of the mitral valve as a cause of transient ischemic stroke

open access: yesArquivos Brasileiros de Cardiologia, 2001
A 44-year-old woman had a transient ischemic stroke, fibroelastoma of the mitral valve being the source of the embolus. The patient evolved with neutropenia induced by ticlopidine after 10 days of treatment.
Alexandre Alessi   +6 more
doaj   +1 more source

AGRANULOCYTOSIS AND MACULOPAPULAR RASH AFTER TREATMENT WITH TICLOPIDINE – CASE REPORT

open access: yesZdravniški Vestnik, 2003
Background. Ticlopidine is one of inhibitors of platelet aggregation indicated for reducing the risk of thrombotic stroke in patients who have experienced thrombotic stroke, ischemic attacks, unstable angina pectoris, coronary artery stenting and ...
Janja Blatnik   +4 more
doaj  

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