Results 41 to 50 of about 12,121 (179)

The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon

open access: yesDermatology Practical & Conceptual, 2015
Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor that may be complicated by Kasabach-Merritt phenomenon (KMP), a profound thrombocytopenia resulting from platelet trapping within a vascular tumor, either KHE or tufted angioma (
Grecia V. Vivas-Colmenares   +4 more
doaj   +1 more source

Medical Adjuvant Therapy in Reducing Thrombosis With Arteriovenous Grafts and Fistulae Use: A Meta-Analysis of Randomized Controlled Trials

open access: yesClinical and Applied Thrombosis/Hemostasis, 2021
Hemodialysis is required for patients with end-stage renal disease (ESRD) that require arteriovenous (AV) grafts or fistulas for vascular access. These access points are prone to thrombosis. To determine the effect of medical adjuvant therapy on AV graft/
Kaleem Ullah MBBS   +6 more
doaj   +1 more source

Dataset of endo- and xenobiotic inhibition of CYP2B6: Comparison to CYP3A4

open access: yesData in Brief, 2022
Cytochrome P450 2B6 (CYP2B6) is a human enzyme important in chemical detoxification, steroid and fatty acid metabolism that is primarily hepatic. Therefore, induction or inhibition of CYP2B6 may perturb endo- and xenobiotic metabolism and cause adverse ...
Emily M. Olack   +2 more
doaj   +1 more source

7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]

open access: yes, 2019
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael   +12 more
core   +3 more sources

Antinuclear Antibody-Positive Ticlopidine-Induced Hepatitis

open access: yesCanadian Journal of Gastroenterology, 1996
Ticlopidine hydrochloride has been shown to reduce the risk of first or recurrent stroke in patients who have experienced a transient ischemic attack, reversible ischemic neurological deficit, recurrent stroke or first stroke. Severe liver dysfunction is
Sander Jo Veldhuyzen van Zanten   +1 more
doaj   +1 more source

Platelet inhibitors versus anticoagulants for prevention of aorto-coronary bypass graft occlusion [PDF]

open access: yes, 2017
The effects of the antiaggregant substance ticlopidine and of the anticoagulant acenocoumarol on patency rates of aorto-coronary bypass grafts were compared in a prospective randomized trial. Ticlopidine, 250 mg b.i.d.
GOEBEL, N.   +7 more
core  

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park   +2 more
wiley   +1 more source

BUSM News and Notes [PDF]

open access: yes, 1982
Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
core  

Antiaggregant therapy in neurological practice: objectives and possibilities

open access: yesНеврология, нейропсихиатрия, психосоматика, 2010
Based on the data available in the literature, the authors consider the prevention of ischemic stroke and other cardiovascular diseases in high-risk group patients.
E. V. Portnyagina, A. F. Portnyagin
doaj   +1 more source

Warfarin interactions: a letter to editor [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2019
Today, with the advances in the treatment of cardiovascular patients such as intravascular stents, cardiac valves and intraventricular pacing and heart transplantation, many patients require the use of anticoagulants such as warfarin, sprain, Plavix ...
Sayyed Majid Sadrzadeh   +4 more
doaj   +1 more source

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