Results 21 to 30 of about 12,121 (179)

Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke:Pooled analysis of randomized trials [PDF]

, 2015
Background and Purpose: Lacunar stroke accounts for ≈25% of ischemic stroke, but optimal antiplatelet regimen to prevent stroke recurrence remains unclear.
Benavente, Oscar R., Copley, Hannah Charlotte, Kwok, Chun Shing, Loke, Yoon K., Myint, Phyo Kyaw, Shoamanesh, Ashkan   +5 more
core   +1 more source

Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review

Dermatologica Sinica, 2014
Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus.
Yi-Ching Chen, Yu-Hung Wu
doaj   +1 more source

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank [PDF]

, 2003
Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies.
Busse, O., Diener, H. C., Glahn, J., Hamann, Gerhard F., Weimar, C.   +4 more
core   +1 more source

Results of the Ticlid or Plavix Post-Stents (TOPPS) trial: do they justify the switch from ticlopidine to clopidogrel after coronary stent placement?

Current Controlled Trials in Cardiovascular Medicine, 2000
In the Ticlid or Plavix Post-Stents (TOPPS) trial, 1016 patients undergoing successful coronary stent placement were randomized to receive aspirin and either ticlopidine or clopidogrel.
Berger Peter B
doaj   +1 more source

Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]

, 2009
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B., Demchuk, A., Kasner, S.E., Lees, K.R., Levine, S.R., Lyden, P., Messe, S.R., Sansing, L., Tanne, D.   +8 more
core   +1 more source

Ticlopidine-Induced Cholestatic Inflammatory Hepatitis: New Insights into Pathogenetic Mechanisms of Drug-Related Hepatotoxicity

European Journal of Inflammation, 2006
In immune-induced liver damage the reactive metabolites may covalently bind or alter liver proteins such as cytochrome P450 enzymes, which leads to activation of the immune system. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome.
I. Kraslova, L. Muchova, L. Vitek, A. Novotny, T. Svestka, R. Bruha   +5 more
doaj   +1 more source

Detecting Adverse Drug Events Through the Chronological Relationship Between the Medication Period and the Presence of Adverse Reactions From Electronic Medical Record Systems: Observational Study

JMIR Medical Informatics, 2021
BackgroundMedicines may cause various adverse reactions. An enormous amount of money and effort is spent investigating adverse drug events (ADEs) in clinical trials and postmarketing surveillance.
Kei Teramoto, Toshihiro Takeda, Naoki Mihara, Yoshie Shimai, Shirou Manabe, Shigeki Kuwata, Hiroshi Kondoh, Yasushi Matsumura   +7 more
doaj   +1 more source

Comparison of Clopidogrel and Ticlopidine/Ginkgo Biloba in Patients With Clopidogrel Resistance and Carotid Stenting

Frontiers in Neurology, 2019
Background and Purpose: Patients undergoing carotid artery stenting (CAS) who show low responsiveness to clopidogrel may have a higher risk of peri-procedural embolic events.
Jong-Won Chung, Suk Jae Kim, Jaechun Hwang, Mi Ji Lee, Jun Lee, Kyung-Yul Lee, Man-Seok Park, Sang Min Sung, Keon Ha Kim, Pyoung Jeon, Oh Young Bang   +10 more
doaj   +1 more source

The effect of antiaggregational therapy on the long-term patency of the femoropopliteal/crural bypass [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2012
Introduction. Antiaggregational therapy can reduce thrombosis development following the arterial reconstruction surgery. In most cases acetylsalicylic acid and ticlopidine are used as antiaggregational agents. Objective.
Vasić Dragan, Radmili Oliver, Davidović Lazar, Vraneš Milica   +3 more
doaj   +1 more source

Anticoagulant versus antiplatelet therapy for acute ischemic stroke [PDF]

, 2008
Acute ischaemic stroke is a leading cause of death in Canada and should be a priority in health care. This paper defines acute ischaemic stroke and provides current statistics, economic costs, risk factors, treatments, and management options.

core   +1 more source